The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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Effects of Different Lengths of Treatment with Rhizoma Alismatis on Diabetic Mellitus of Streptozotocin-Induced Hyperglycemic Rats

택사(澤瀉) 시간별 투여(投與)가 Streptozotocin으로 유발된 고혈당 백서(白鼠)의 실험적(實驗的) 당뇨(糖尿)에 미치는 영향(影響)

  • Nam, Jeong-Woo (Department of Internal Medicine, Kyungwon University Oriental Medicine Hospital) ;
  • Rhee, See-Hyung (Department of Internal Medicine, Kyungwon University Oriental Medicine Hospital) ;
  • Kang, Mi-Suk (Department of Acupuncture & Moxibustion, Kyungwon University Oriental Medicine Hospital) ;
  • Choi, You-Kyung (Department of Internal Medicine, Kyungwon University Oriental Medicine Hospital) ;
  • Jun, Chan-Yong (Department of Internal Medicine, Kyungwon University Oriental Medicine Hospital) ;
  • Park, Chong-Hyeong (Department of Internal Medicine, Kyungwon University Oriental Medicine Hospital) ;
  • Kim, Dong-Woo (Department of Internal Medicine, Kyungwon University Oriental Medicine Hospital)
  • 남정우 (경원대학교 한의과대학 내과학교실) ;
  • 이시형 (경원대학교 한의과대학 내과학교실) ;
  • 강미숙 (경원대학교 한의과대학 침구과교실) ;
  • 최유경 (경원대학교 한의과대학 내과학교실) ;
  • 전찬용 (경원대학교 한의과대학 내과학교실) ;
  • 박종형 (경원대학교 한의과대학 내과학교실) ;
  • 김동우 (경원대학교 한의과대학 내과학교실)
  • Published : 2006.12.31
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Abstract

Objectives : The objective of the study was to observe the effects of different treatment lengths of Rhizoma Alismatis on diabetes mellitus. Methods : Rats were divided into three groups: normal(non-treated group), control (group administered saline for 4, 11, and 18 days), and RA (group administered 2.45mg/200g Rhizoma Alismatis for 4, 11, and 18 days). The experimental results were derived from the measurement of the levels of glucose, ALP, AST, ALT, creatinine and BUN in the serum from the rats on days 4, 11, and 18. Results : The glucose level in the serum significantly decreased on the 18th day. The ALP level in the serum did not show statistical significance. The GOT and GPT levels in the serum slightly decreased on the 4th, 11th, and 18th days, but did not show statistical significance. The creatinine level in the serum was unchanged for all of them. The BUN level in the serum did not show statistical significance. Conclusions : According to the above results, it is concluded that Rhizoma Alismatis has a therapeutic effect on diabetes mellitus with a longer period ofintake. As to influence upon the liver and kidney, there was no damage orside effects.

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