DOI QR코드

DOI QR Code

Effects of Fine Particles on Pulmonary Function of Elementary School Children in Ulsan

미세먼지가 울산지역 초등학생의 폐기능에 미치는 영향

  • Yu, Seung-Do (Environmental Epidemiology Division, Environmental Health Research Department, National Institute of Environmental Research) ;
  • Cha, Jung-Hoon (Environmental Epidemiology Division, Environmental Health Research Department, National Institute of Environmental Research) ;
  • Kim, Dae-Seon (Environmental Epidemiology Division, Environmental Health Research Department, National Institute of Environmental Research) ;
  • Lee, Jong-Tae (Department of Health, Graduate School, Hanyang University)
  • 유승도 (국립환경과학원 환경건강연구부 환경역학과) ;
  • 차정훈 (국립환경과학원 환경건강연구부 환경역학과) ;
  • 김대선 (국립환경과학원 환경건강연구부 환경역학과) ;
  • 이종태 (한양대학교 대학원 보건학과)
  • Published : 2007.10.30

Abstract

To evaluate the effect of air pollution on respiratory health in children, We conducted a longitudinal study in which children were asked to record their daily levels of Peak Expiratory Flow Rate(PEFR) using potable peak flow meter(mini-Wright) for 4 weeks. The relationship between daily PEFR and ambient air particle levels was analyzed using a mixed linear regression models including gender, age in year, weight, the presence of respiratory symptoms, and relative humidity as an extraneous variable. The daily mean concentrations of $PM_{10}$ and $PM_{2.5}$ over the study period were $64.9{\mu}g/m^3$ and $46.1{\mu}g/m^3$, respectively. The range of daily measured PEFR in this study was $182{\sim}481\;l/min$. Daily mean PEFR was regressed with the 24-hour average $PM_{10}(or\;PM_{2.5})$ levels, weather information such as air temperature and relative humidity, and individual characteristics including sex, weight, and respiratory symptoms. The analysis showed that the increase of air particle concentrations was negatively associated with the variability in PEFR. We estimated that the IQR increment of $PM_{10}$ or $PM_{2.5}$ were associated with 1.5 l/min (95% Confidence intervals -3.1, 0.1) and 0.8 l/min(95% CI -1.8, 0.1) decline in PEFR. Even though this study showed negative findings on the relationship between respiratory function and air particles, it was worth noting that the findings must be interpreted cautiously because exposure measurement based on monitoring of ambient air likely resulted in misclassification of true exposure levels and this was the first Korean study that $PM_{2.5}$ measurement was applied as an index of air quality.

Keywords

References

  1. Peters, A., Dockery, D. W., Heinrich, J. and Wichmann, H. E. : Short-term effects of particulate air pollution on respiratory morbidity in asthmatic children. The European Respiratory Journal, 10(4), 872-879, 1997
  2. Droste Jos, H. J., Wieringa, M. H., Weyler, J. J., Nelen, V. J., Van Bever, H. P. and Vermeire, P. A. : Lung function measures and their relationship to respiratory symptoms in 7- and 8-year-old children. Pediatric Pulmonology, 27, 260-266, 1999
  3. Von Klot, S., Wolke, G., Tuch, T., Heinrich, J., Dockery, D. W., Schwartz, J., Kreyling, W. G., Wichmann, H. E. and Peters, A. : Increased asthma medication use in association with ambient fine and ultrafine particles. The European Respiratory Journal, 20(3), 691-702, 2002 https://doi.org/10.1183/09031936.02.01402001
  4. 강공언, 이상복 : 호흡기 침착부위에 따른 미세먼지 중수용성 이온성분의 일별 농도 측정. 한국환경보건학회지, 31(5), 387-397, 2005
  5. Dockery, D. W., Pope, C. A. 3rd, Xu, X., Spengler, J. D., Ware, J. H., Fay, M. E., Ferris, B. G. Jr and Speizer, F. E. : An association between air pollution and mortality in six U.S. cities. The New England Journal of Medicine, 329, 1753-1759, 1993 https://doi.org/10.1056/NEJM199312093292401
  6. Samet, J. M., Dominici, F., Curriero, F. C., Coursac, I. and Zeger, S. L. : Fine particulate air pollution and mortality in 20 U.S. cities: 1987-1994. The New England Journal of Medicine, 343, 1742-1749, 2000 https://doi.org/10.1056/NEJM200012143432401
  7. McConnell, R., Berhane, K., Gilliland, F., London, S. J., Vora, H., Avol, E., Gauderman, W. J., Margolis, H. G., Lurmann, F., Thomas, D. C. and Peters, J. M. : Air pollution and bronchitic symptoms in Southern California children with asthma. Environmental Health Perspectives, 107, 757-760, 1999 https://doi.org/10.2307/3434662
  8. Gent, J. F., Triche, E. W., Holford, T. R., Belanger, K., Bracken, M. B., Beckett, W. S. and Leaderer, B. P. : Association of low-level ozone and fine particles with respiratory symptoms in children with asthma. The JOURNAL of the American Medical Association, 290(14), 1915-1917, 2003 https://doi.org/10.1001/jama.290.14.1915
  9. Kwon, H. J. : Air pollution. The Korean Association of Medical Journal, 41(10), 1025-1031, 1998 https://doi.org/10.5124/jkma.1998.41.10.1025
  10. 이영길, 백남원 : 중학교 학생들의 분진폭로에 관한 조사연구. 한국환경보건학회지, 13(2), 25-33, 1987
  11. Lee, J. T. and Kim, H. : Epidemiologic methods and study designs for investigating adverse health effects of ambient air pollution. The Korean Society for Preventive Medicine, 34(2), 119-126, 2001
  12. Hong, Y. C. and Cho, S. H. : Health effects of ambient particulate pollutants. The Korean Society for Preventive Medicine, 34(2), 103-108, 2001
  13. Pope, C. A. 3rd and Schwartz, J. : Time series for the analysis of pulmonary health data. American Journal of Respiratory and Critical Care Medicine. 154(6 Pt 2), s229-s233, 1996 https://doi.org/10.1164/ajrccm/154.6_Pt_2.S229
  14. Bascom, R., Bromberg, P. A., Costa, D. A., Devlin, R., Dockery, D. W., Framptom, M. W., Lambert, W., Samet, J. M., Speizer, F. E. and Utell, M. : Health effects of outdoor air pollution. American Journal of Respiratory and Critical Care Medicine, 153, 3-50, 1996 https://doi.org/10.1164/ajrccm.153.1.8542133
  15. 김대선, 유승도, 차정훈, 안승철, 차준석 : 봄철 미세분진이 북경시 아동 폐기능에 미치는 급성영향에 관한 연구. 한국환경보건학회지, 30(2), 140-148, 2004
  16. 김신도 : 우리나라 미세먼지 현황 및 문제점. 한국대기환경학회 추계학술대회. 한국대기환경학회, 2004
  17. 신문기, 이충대, 하현섭, 최춘석, 김용희 : 기상인자가 미세먼지 농도에 미치는 영향. 한국대기환경학회지, 23(3), 322-331, 2007 https://doi.org/10.5572/KOSAE.2007.23.3.322
  18. 김성연, 정문호, 손부순, 양원호, 최경호 : 서울시 일부지역의 대기 중 미세먼지에 관한 연구. 한국환경보건학회지, 31(4), 301-308, 2005
  19. 최금찬, 김종호, 김태식, 강공언, 강창희, 김신도 : 미세먼지 분야 측정분석 자료의 해석. 한국대기환경학회 춘계학술대회. 한국대기환경학회, 2003
  20. Dockery, D. W., Speizer, F. E., Stram, D. O., Ware, J. H., Spengler, J. D. and Ferris, B. G. Jr. : Effects of inhalable particles on respiratory health of children. The American Review of Respiratory Disease, 139, 587-594, 1989 https://doi.org/10.1164/ajrccm/139.3.587
  21. Schwartz, J. : Lung function and chronic exposure to air pollution: a cross-sectional analysis of NHANES II. Environmental Research, 50, 309-321, 1989 https://doi.org/10.1016/S0013-9351(89)80012-X
  22. Chestnut, L. G., Schwartz, J., Savitz, D. A. and Burchfiel, C. M. : Pulmonary function and ambient particulate matter: epidemiological evidence from NHANES I. Archives of Environmental Health, 46, 135-144, 1991 https://doi.org/10.1080/00039896.1991.9937440
  23. Ackermann-Liebrich, U., Leuenberger, P., Schwartz, J., Schindler, C., Monn, C., Bolognini, G., Bongard, J. P., Brandli, O., Domenighetti, G., Elsasser, S., Grize, L., Karrer, W., Keller, R., Keller-Wossidlo, H., Kunzli, N., Martin, B. W., Medici, T. C., Perruchoud, A. P., Schoni, M. H., Tschopp, J. M., Villiger, B., Wuthrich, B., Zellweger, J. P. and Zemp, E. : Lung function and long term exposure to air pollutants in Switzerland. American Journal of Respiratory and Critical Care Medicine, 155, 122-129, 1997 https://doi.org/10.1164/ajrccm.155.1.9001300
  24. Pope, C. A. 3rd and Dockery, D. W. : Epidemiology of particle effects. Air Pollution and Health. Academic Press, London, 673-706, 1999
  25. Peters, J. M., Avol, E., Gauderman, W. J., Linn, W. S., Navidi, W., London, S. J., Margolis H., Rappaport, E., Vora, H., Gong, H. Jr. and Thomas, D. C. : A study of twelve Southern California communities with differing levels and types of air pollution; II. effects on pulmonary function. American Journal of Respiratory and Critical Care Medicine, 159, 768- 775, 1999 https://doi.org/10.1164/ajrccm.159.3.9804144
  26. Dockery, D. W. and Pope, C. A. 3rd. : Acute respiratory effects of particulate air pollution. Annual Review of Public Health. 15, 107-132, 1994 https://doi.org/10.1146/annurev.pu.15.050194.000543
  27. Vedal, S., Petkau, J., White, R. and Blair, J. : Acute effects of ambient inhalable particles in asthmatic and nonasthmatic children. American Journal of Respiratory and Critical Care Medicine, 157(4 Pt 1), 1034-1043, 1998 https://doi.org/10.1164/ajrccm.157.4.9609008
  28. Lee, C. R., Yoo, C. I., Lee, J. H. and Kim, Y. H. : Respiratory health of the children living near the petrochemical estate in Ulsan. The Korean Society for Preventive Medicine, 33(2), 174-183, 2000

Cited by

  1. Exposure Assessment of Heavy Metals using Exposure Biomarkers among Residents Living Near a Chungcheongnam-do Province Industrial Complex Area vol.42, pp.3, 2016, https://doi.org/10.5668/JEHS.2016.42.3.213
  2. Concentration and Distribution Characteristics of PM10in High Schools in the Ulsan Metropolitan Area vol.38, pp.1, 2012, https://doi.org/10.5668/JEHS.2012.38.1.042
  3. Effects of Environmental Air Pollution on Pulmonary Function Level of Residents in Korean Industrial Complexes vol.15, pp.5, 2018, https://doi.org/10.3390/ijerph15050834