Obstetrics & gynecology science

Korean Society of Obstetrics and Gynecology (대한산부인과학회)
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Papillary carcinoma arising in a struma ovarii of the complex teratoma

난소 복합기형종의 갑상샘증에서 발생한 유두암

Hong, Ran;Song, Chang-Hoon;Kee, Keun-Hong;Lee, Mi-Ja;Lim, Sung-Chul
홍란;송창훈;기근홍;이미자;임성철

  • Published : 20071100
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Abstract

Benign or malignant tumors that arise in a benign cystic teratoma are rare. Malignant transformation in mature cystic teratoma of ovary is reported to occur in 1~3%. Several types of malignancy can occur from any of three germ-cell layers, but the most common malignancy is a squamous cell carcinoma derived from ectoderm. We experienced a papillary carcinoma arising in a struma ovarii of the complex teratoma. 74-year-old female presented with an abdominal discomfort. A pelvic ultrasonograph and computed tomography detected a 7×6cm-sized and well-circumscribed cystic mass at the anterior to the uterus. The inner part of the mass was filled with cystic fluid showing low-density, however, solid portion including fat and soft tissue accompanied by calcification was identified in more than half of the entire tumor volume. The patient underwent a bilateral salpingo-oophorectomy. On histopathologic examination, the lesion was consistent with papillary carcinoma with squamoid features arising in a struma ovarii of the mature cystic teratoma. We herein report a case of the very rare papillary carcinoma arising in a struma ovarii of the complex teratoma and review the available literature.

양성 낭성기형종에서 발생하는 양성 혹은 악성종양은 드물며 난소의 성숙 낭성 기형종에서의 악성전환은 1~3% 정도로 알려져 있다. 기형종에서 악성 전환하는 경우 3가지 생식세포계열의 어디에서도 여러 형태의 악성종양이 발생할 수 있으나 가장 흔한 것은 외배엽에서 기원하는 편평세포암종이다. 저자들은 복합기형종에서 발생한 유두암종을 경험하였다. 74세 여성이 복부불편감을 주소로 내원하였으며 골반초음파검사상 각각 5 cm와 7 cm 크기의 종괴가 양쪽 난소에서 관찰되어 양측 난소와 난관절제술을 시행받았다. 조직학적 검사상 병변은 복합기형종의 난소갑상샘증에서 유래한 편평세포형의 분화를 보이는 유두암종의 소견을 보였다. 복합기형종의 난소갑상샘증에서 유래하는 유두암종은 매우 드문 증례로서 그 희귀성에 비추어 문헌고찰과 함께 보고하는 바이다.

Keywords

References

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