Journal of Korean Society of Occupational and Environmental Hygiene (한국산업보건학회지)

Korean Industrial Hygiene Association (한국산업보건학회)
권호 표지

Biological monitoring of miners exposed to diesel exhaust using urinary 1-hydroxypyrene

디젤 연소물질에 노출된 광산 근로자에서 소변 중 1-hydroxypyrene을 이용한 생물학적 모니터링

  • Lee, Jong Seong (Center for Occupational Lung Diseases, Workers Accident Medical Corporation) ;
  • Choi, Byung-Soon (Center for Occupational Lung Diseases, Workers Accident Medical Corporation) ;
  • Shin, Jae-Hoon (Center for Occupational Lung Diseases, Workers Accident Medical Corporation) ;
  • Shin, Yong Chul (Department of Occupational Health and Safety Engineering, Inje University) ;
  • Kim, Ki-Woong (Occupational Safety and Health Research Institute, Korea Occupational Safety and Health Agency)
  • 이종성 (산재의료관리원 직업성폐질환연구소) ;
  • 최병순 (산재의료관리원 직업성폐질환연구소) ;
  • 신재훈 (산재의료관리원 직업성폐질환연구소) ;
  • 신용철 (인제대학교 보건안전공학과) ;
  • 김기웅 (한국산업안전공단 산업안전보건연구원)
  • Received : 2007.03.13
  • Accepted : 2007.06.18
  • Published : 2007.06.30
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Abstract

Diesel vehicles are a significant source of fine carbon particle emissions including polynuclear aromatic hydrocarbons (PAHs). Urinary 1-hydroxypyrene (1-OHP) is firmly established as a useful biomarker of PAHs uptake in human. To investigate the exposure effect of PAHs in miners according to using diesel truck which was for transportation of ore, we measured urinary 1-OHP as the PAHs exposure biomarker, and analyzed the relationship between urinary 1-OHP concentration and using diesel truck. The study was performed on 118 workers (56 miners in factories using diesel truck, 62 miners in factories non-using diesel truck) and 21 controls. Urine samples were obtained at the end of shift on the survey day. There was no significance in comparison with the mean concentrations on urinary 1-OHP by age, BMI, work duration, smoking, drinking and ventilation type. But significant difference were found among urinary 1-OHP concentrations on factories according to using diesel truck (p=0.000). The urinary 1-OHP mean concentration on underground miners using diesel truck ($0.54{\mu}mol/mol$ creatinine) was higher than those of surface miners using diesel truck ($0.33{\mu}mol/mol$ creatinine, p=0.028), underground miners non-using diesel truck ($0.32{\mu}mol/mol$ creatinine, p=0.001) and controls ($0.22{\mu}mol/mol$ creatinine, p=0.000). In comparison with using status diesel truck, the urinary 1-OHP mean concentration of underground miners using diesel trucks was higher than those of other mine status. The study results would be beneficial to future environmental and biological studies of PAHs exposure to diesel exhaust in mines.

Keywords

Acknowledgement

Supported by : 산업안전보건연구원

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