Journal of asthma, allergy and clinical immunology (천식및알레르기)

The Korean Academy of Asthma, Allergy and Clinical Immunology (대한천식알레르기학회)
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The Prevalence of Respiratory Viral Infection in Exacerbation of Asthma in Hospitalized Children

천식으로 입원한 소아에서 호흡기 바이러스 감염의 유병률

Roh, Eui-Jung;Jin, Yong-Man;Rheem, In-Soo;Kim, Jae-Kyung;Chung, Eun-Hee
노의정;진용만;임인수;김재경;정은희

  • Published : 20071200
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Abstract

Background: Respiratory viral infections are common exacerbating factors for asthma in children. Recently the detection of respiratory viruses can be improved by using molecular biology techniques, which providing a method capable of detecting an increasing number of viruses. Objectives : The aim of this study was to evaluate the causative viral infections and their seasonal trends in children who were admitted with the exacerbation of their asthma by multiplex polymerase chain reaction (PCR) assay. Methods: Nasopharyngeal aspirates were obtained from hospitalized asthmatic children at Dankook University Hospital from November 2005 through Febraury 2007. Multiplex PCR assay was used for the detection of respiratory viruses. The demographic and clinical characteristics were reviewed retrospectively from the patients’ medical records. Results: During the study period, 58 were hospitalized due to acute asthma exacerbations. Of these, infectious agents were detected in 38 (65.5%) of the patients. Resipiratoy syncytial virus was detected in 18 (31%), influenza virus in 10 (17.2%), rhinovirus in 7 (12.1%), coronavirus in 5 (8.6%), adenovirus in 4 (6.9%), parainfluenza virus in 5 (8.6%) and human metapneumovirus in 2 (3.4%). Conclusion: It is suggested that the causative virus in hospitalized children with asthma exacerbations follow may the epidemic of respiratory virus in hospitalized children with respiratory infection.

Keywords

References

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