Journal of Microbiology

The Microbiological Society of Korea (한국미생물학회)
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The Antimicrobial Activity of Essential Oil from Dracocephalum foetidum against Pathogenic Microorganisms

  • Lee, Saet-Byoul (Natural Products Research Center, KIST Gangneung Institute, Gangneung Techno Valley) ;
  • Cha, Kwang-Hyun (Natural Products Research Center, KIST Gangneung Institute, Gangneung Techno Valley) ;
  • Kim, Su-Nam (Natural Products Research Center, KIST Gangneung Institute, Gangneung Techno Valley) ;
  • Altantsetseg, Shataryn (Institute of Chemical and Chemical Technology) ;
  • Shatar, Sanduin (Institute of Chemical and Chemical Technology) ;
  • Sarangerel, Oidovsambuu (Mongolian National University) ;
  • Nho, Chu-Won (Natural Products Research Center, KIST Gangneung Institute, Gangneung Techno Valley)
  • Published : 2007.02.22
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Abstract

A number of essential oils from Mongolian aromatic plants are claimed to have antimicrobial activities. The essential oil of Dracocephalum foetidum, a popular essential oil used in Mongolian traditional medicine, was examined for its antimicrobial activity. Eight human pathogenic microorganisms including B. subtilis, S. aureus, M. lutens, E. hirae, S. mutans, E. coli, C. albicans, and S. cerevisiae were examined. The essential oil of Dracocephalum foetidum exhibited strong antimicrobial activity against most of the pathogenic bacteria and yeast strains that were tested; by both the agar diffusion method and the minimum inhibitory concentration (MIC) assay ($MIC\;range\;was\;26-2592{\mu}g/ml$). Interestingly, Dracocephalum foetidum even showed antimicrobial activity against methicilin-resistant Staphylococcus aureus (MRSA) strains. We also analyzed the chemical composition of the oil by GC-MS and identified several major components, including n-Mentha-1,8-dien-10-al, limonene, geranial, and neral.

Keywords

References

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