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Concentration of Heavy Metals in Sagunjatang, Decoction and Its Ingredient Herbal Medicines

사군자탕 제조 시 탕약과 찌꺼기 중의 중금속 함량연구

  • Park, Moon-Ki (Department of Health Environment, Deagu Haany University)
  • 박문기 (대구한의대학교 보건환경학과)
  • Published : 2007.02.28

Abstract

We studied concentration of heavy metals in Sagunjatang. In this experiment was analyzed the concentration of heavy metals of boiled Sagunjatang, decoction and its ingredient herbal medicines. The concentration of heavy metals(As, Pb, and Cd) were analysed using ICP-AES, and Hg was analysed by mercury analyzer. The average concentration of heavy metals in Sagunjatang were as follows : In all ingredient herbal medicines (Glycyrrhizae Radix, Atractylodes Macrocephala, Poria Cocos and Jinseng) of Sagunjatang, As(arsenite) contents in ail samples was in the range of 0.369-0.723ppm, Cd(cadmium) was in the range of 0.000-0.085ppm, Pb(lead) was in the range of 0.059-0.871ppm and Hg(mercury) was in the range of 0.001-0.004ppm. In boiled Sagunjatang, the concentration of heavy metals(As, Pb, Cd and Hg) was in the range of 0.000-0.016ppm, respectively. In the decoction of herbal medicines after boiled, the concentration of heavy metals was in the range of 0.004-0.387ppm. These results suggest that Sagunjatang which we take is less harmful than herbal medicine itself, and there are more significant for using the decoction of herbal medicines.

Keywords

References

  1. 주윤정,오정미,하병현,홍성선,2001,생약제제의 등록규정 차별화에 관한 연구,한국임상약학회지,11(2),68-77
  2. 김진숙,황성원,김종문,마진열,2001,한약재와 당액(섭전대보탕) 중 내분비계 장애물질로서의 개별 중금속 함량분석(II),약학회지 ,45(5),448-454
  3. 박해모,최경호,정진용,이선동,2006,한약재 복용으로 인한 금속 섭취량 추정 및 위해성 평가 연구,한국환경보건학회지,32(2),186-191
  4. 국립환경연구원,2005,내분비계장애물질의 이해,행정간행물등록번호,11-1480 083-000285-01
  5. Rhee, S. J., S. O. Kim and W. K. Choe, 1992, Effect of cadmium dose injection on peroxidative damage in rat liver (in Korean), J. Korean Soc. Food Sci. Nutr. 21, 601-607
  6. Jung, S. Y., S. J. Rhee, and J. A. Yang, 1990, Effect of dietary vitamin E levels on lipid peroxidation and enzyme activities of antitoxidative system in brain of cadmium administered rats (in Korean), J. Korean Soc. Food Sci. Nutr., 25, 575-580
  7. Rabinowits, M. B. and G. W. Weatherill, 1973, Lead metabolism in the normal human: stable isotope studies, Science, 182, 275
  8. Chio, S. I., J. H. Lee, and S. R. Lee, 1994, Effect of green tea beverage for the removal of cadmium and lead by animal experiments (in Korean), Korean J. Food Sci. Technol., 26, 745-749
  9. Schroeder, H. A. and W. H. Vinton, 1962, Hypertension induced in rats by small doses of cadmium, Am. J. Physiol., 202, 515-518
  10. Nordberg, M., 1984, General aspects of cadmium: transport, uptake and metabolism by the kideny, Environ., Health Persp., 54, 1320
  11. 강상훈,이상순,조승연,정용삼,2002,인체 환 경 연구를 위한 한약재,작업장 공기 및 모발의 원소 분석, 한국환경보건학회지,28(3),64-71
  12. 식약청,2005,생약 등의 중금속 허용 기준 및 시험방법 개정,식품의약품안전청고시 제 200562호
  13. 최성인,황진봉,권중호,김현구,1998,생약재에 의한 중금속의 체내흡수 억제 효과,한국식품과학회지,30(2),456-460
  14. 김승영,2005,한약재 중의 유해물질에 대한 안전성 연구,석사학위논문,대구한의대학교
  15. Fernando L. M. and S. C. Sara, 1996, Fetal abnormalities and use of substances sold in herbal remedies shops, Drug safety, 14, 6875
  16. Ahmed, 2002, Maternal bone lead as an independent risk factor for fetal neurotoxicity: a prospective study, Pediatrics, 110, 110-117 https://doi.org/10.1542/peds.110.1.110