Effects of Different Kinds of Korean Soybeans on Body Lipids and Lipid Peroxidation in Rats

다양한 콩종류가 흰쥐의 체내지질과 지질과산화에 미치는 영향

  • Kim, Hye-Young P. (Department of Food and Nutrition, Yongin University) ;
  • Han, Yoon-Hee (Department of Food and Nutrition, Yongin University) ;
  • Kim, Myung-Hee (Department of Food Service Management and Culinary Arts, Kyonggi University) ;
  • Kim, Kang-Sung (Department of Food and Nutrition, Yongin University)
  • 김혜영 (용인대학교 식품영양학과) ;
  • 한윤희 (용인대학교 식품영양학과) ;
  • 김명희 (경기대학교 외식조리학과) ;
  • 김강성 (용인대학교 식품영양학과)
  • Published : 2007.04.30

Abstract

This study was conducted to investigate the effect of different kinds of traditional Korean soybeans on blood and liver lipids and lipid peroxidation. SD male rats (n=48) were assigned to six different groups and provided experimental diets for 28 days. The protein source of the diet was casein, isolated soy protein (ISP), or casein plus traditional soy powders (yellow bean, huktae, jinuni or seorietae). The ISP, jinuni and seorietae diet decreased blood triglyceride compared to casein group. The ISP groups had lower hepatic total lipid and triglycerides than casein groups. The yellow bean and seorietae group had hepatic lipid lowering effects, but the effect was not found in huktae and jinuni group. The glutamate-oxaloacetate transaminase activity was significantly decreased in ISP and jinuni groups than in casein group. The glutamate-pyruvate transaminase activity was also decreased in ISP group. The results of this study suggest that jinuni, yellow bean and seorietae groups are more effective in lowering body lipids than huktae group.

Keywords

References

  1. Kwon TW. Soybean in the 21st century. Korean Soybean Digest 2000; 17: 1-4
  2. Carroll KK, Giovannetti PM, Huff MW, Moase O, Roverts DC, Wolfe BM. Hypocholesterolemic effect of substituting soybean protein for animal protein in the diet of healthy young women. Am J Clin Nutr 1978; 31: 1312-1321 https://doi.org/10.1093/ajcn/31.8.1312
  3. Terpstra AHM, Gerrit T, Clive EW. The hypocholesterolemic effects of dietary soy protein in rats. Am J Clin Nutr 1982; 112: 810-817
  4. Potter SM. Soy protein and serum lipids. Am J Clin Nutr 1996; 7: 260-264
  5. Carroll KK. Review of clinical studies on cholesterol-lowering response to soy protein. Am J Clin Nutr 1991; 91: 820-827
  6. Anderson JW, Johnstone BM, Cook-Newell ME. Meta-analysis of the effects of soy protein intake on serum lipids. N Engl J Med 1995; 333: 276-282 https://doi.org/10.1056/NEJM199508033330502
  7. Potter SM, Bakhit RM, Essex-Sorlie D. Depression of plasma cholesterol in men by consumption of baked products containing soy protein. Am J Clin Nutr 1993; 58: 501-506 https://doi.org/10.1093/ajcn/58.4.501
  8. Bakhit RM, Klein BP, Essex-Sorlie D, Ham JO, Erdman JW Jr, Potter SM. Intake of 25g soybean protein with or without soybean fiber alters plasma lipids in men with elevated cholesterol concentrations. J Nutr 1994; 124: 213-222 https://doi.org/10.1093/jn/124.2.213
  9. Barnes S. Evolution of the health benefits of soy isoflavones. Proc Soc Exp Biol Med 1998; 217: 386-392
  10. Kim JY, Kim WK, Kim HYP, Kim MH, Kim SH. Effects of soyoligosaccharides and varying dietary fats on intestinal microflora lipid profiles and immune responses in rats. Korean J Nutr 2000; 33: 597-612
  11. Kim MH, Kim HYP, Kim YH, Kim WK, Kim JY, Kim SH. Effects of soyoligosaccharides on blood glucose and lipid metabolism in streptozotocin-induced diabetic rats. Korean J Nutr 2001; 34: 3-13
  12. Potter SM. Overview of proposed mechanisms for the hypocholesterolemic effect of soy. J Nutr 1995; 125: 606s-611s
  13. Klein KO. Isoflavones, soy-based infant formulas, and relevance to endocrine function. Nutr Rev 1998; 56: 193-204 https://doi.org/10.1111/j.1753-4887.1998.tb01748.x
  14. Potter SM, Baum JA, Teng H, Stillman RJ, Shay NF, Erdman JW. Soy protein and isoflavones: their effects on blood lipids and bone density in postmenopausal women. Am J Clin Nutr 1998; 68: 1375s-1379s
  15. Lee YS, Xiaowei C, Anderson J. Physiological concentrations of genistein stimulate the proliferation and protect against free radical-induced oxidative damage of MC3T3-E1 osteoblast-like cells. Nutr Res 2001; 21: 1287-1298 https://doi.org/10.1016/S0271-5317(00)00299-2
  16. Rodrdanz E, Ohler S, Tran-Thi QH, Kahl R. The phytoestrogen daidzein affects the antioxidant enzyme system of rat hepatoma H4IIE cells. J Nutr 2002; 132: 370-375 https://doi.org/10.1093/jn/132.3.370
  17. Lee YS, Jang SY, Kim KO. Effects of soy isoflavone intake on nitrite content and antioxidant enzyme activities in male rats fed high-fat diet. Korean J Nutr 2005; 38(2): 89-95
  18. Wei H, Cai Q, Rahn R. Inhibition of UV light and Fenton reaction induced oxidative DNA damage by the soybean isoflavone genistein. Carcinogenesis 1996; 17: 73-77 https://doi.org/10.1093/carcin/17.1.73
  19. Kim YH, Yun HT, Park KY, Kim SD. Extraction and separation of anthocyanins in black soybean. Kor J Crop Sci 1997; 39: 35-38
  20. Son JH, Ghoung MG, Choi HJ, Jang UB, Son GM, Byun MW, Choi C. Physiological effect of Korean black soybean pigment. Korean J Food Sci Technol 2001; 33(6): 764-768
  21. Bae EA, Moon GS. A study of the antioxidative activities of Korean soybeans. J Korean Soc Food Sci Nutr 1997; 26: 203-208
  22. Kim MJ. Studies of functional compositions and physicochemical characteristics of Korean traditional soybeans. Masters Thesis of Graduate School. Yongin University, Yongin; 2000
  23. Bligh EG, Dyer WJ. A rapid method of total lipid extraction and purification. Can J Biochem Physiol 1959; 37: 911-917 https://doi.org/10.1139/y59-099
  24. Yagi K. Assay for blood plasma or serum. In: Method in enzymology. Academic Press 1984; 105: 328-331
  25. Lee YS, Koh JS. Effects of dietary soy protein and calcium on blood and tissue lipids in rats fed fat-enriched diet. Korean J Nutr 1994; 27(1): 3-11
  26. Chung EJ, Kim SY, Kim JY, Ahn JY, Park JW, Cha MH, Kim YC. Effects of soy protein concentrate and age on plasma lipids and phospholipid fatty acid patterns in female rats. J Korean Soc Food Sci Nutr 2003; 32(2): 269-277 https://doi.org/10.3746/jkfn.2003.32.2.269
  27. Liener IE. Factors affecting the nutritional quality of soya products. J Am Oil Chem Soc 1981; 58: 406-415 https://doi.org/10.1007/BF02582390
  28. Ko MK, Kwon TW, Song YS. Effects of yellow and black soybeans on plasma and hepatic lipid composition and fecal lipid excretion in rats. J Korean Soc Food Sci Nutr 1998; 27(1): 126- 131
  29. Ryu SH, Moon GS. Antioxidative and antiaging effects of dietary yellow and black soybean in rats. J Korean Soc Food Sci Nutr 2003; 32(4): 591-597 https://doi.org/10.3746/jkfn.2003.32.4.591