Effects of Antioxidant and Antimicrobial of Geum japonicum Thunb

뱀무 추출물의 항산화 활성 및 항균 효과

  • Lee, Jeong-Ho (Department of Natural Health Management, Songho College) ;
  • Lim, Yong-Kwang (Health Administration, Songho College) ;
  • Kim, Yun-Gyoung (Department of Oriental Pharmacy, College of Pharmacy, Wonkwang University) ;
  • Lim, Jin-A (Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Lee, Ki-Nam (Professional Graduate School of Oriental Medicine, Wonkwang University)
  • 이정호 (송호대학 자연건강관리과) ;
  • 임용광 (송호대학 보건행정학과) ;
  • 김윤경 (원광대학교 약학대학 한약학과) ;
  • 임진아 (원광대학교 한의학전문대학원) ;
  • 이기남 (원광대학교 한의학전문대학원)
  • Published : 2007.06.30

Abstract

Herbal medicine has been traditional used for prevention and treatment of treatment of disease, because herbal medicine has few side effects in the human body. Anti-medicines such as antimicrobial medicine and anti-cancer medicine, which contains herbal medicine, are being studied vigorously by researchers. The effects of Geum Japonicum Thumb are restorative, blood circulation and detoxification. It also treats hematemesis, menstruation and furunculus. The ingredients of Geum Japonicum Thumb include geoside and tannin. The study measured antioxidative activation and antifungal activation by using Geum Japonicum Thumb water and methanol extract. The crude extract, which was used for this study, was Korean herbal medicine and the results are as follows. As Geum Japonicum Thumb extracts get stronger, the antioxidative activation tended to increase. The antioxidative activation hit its peak when the density of methanol extract was 120ug/ml. The experiment showed that a 1.0mm clear zone appeared when the density of the Geum Japonicum Thumb methanol extracts were 1000ug/ml in the Staphylococcus epidermidis and 1.1mm clear zone at Pseudomonas aeruginosa. The results of this study concludes that the antioxidative activation is lubricated in the Geum Japonicum Thumb extracts. In addition, the antifungal activation occurred in the fungus of the Staphylococcus epidermidis and the Pseudomonas aeruginosa.

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