YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Antioxidative Activity of Extracts of Acanthopanax divaricatus var. albeofructus Leaves in Human Dermal Fibroblast Irradiated by UVA

자외선이 조사된 사람피부 섬유아세포에서 흰털오가피 잎추출물의 항산화작용

  • Shin, Ai-Hyang (Susin R&D institute, Susin Ogapy) ;
  • Lyu, Su-Yun (School of Pharmacy, University of Nottingham, University Park) ;
  • Noh, Bin-Na (Department of Chemistry, Seoul Women's University) ;
  • Kim, Ja-In (Department of Food Science and Nutrition, Daejin University) ;
  • Kim, Ok-Kyoung (Department of Food Science and Nutrition, Daejin University) ;
  • Park, Won-Bong (Department of Chemistry, Seoul Women's University)
  • 신애향 ((주)수신오가피, 수신오가피 R&D 연구소) ;
  • 유수연 (노팅험대학교 약학대학) ;
  • 노빛나 (서울여자대학교 자연과학대학) ;
  • 김자인 (대진대학교 생활과학대학 식품영양학과) ;
  • 김옥경 (대진대학교 생활과학대학 식품영양학과) ;
  • 박원봉 (서울여자대학교 자연과학대학)
  • Published : 2007.08.31
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Abstract

We investigated antioxidative activity of the water and ethanol extracts of leaves of Acanthopanax divaricatus var. albeofructus in human dermal fibroblast (HDFs) irradiated by UVA. The irradiation of UVA did not affect the cell viability of HDFs. The antioxidative activity of the extract was investigated by xylenol orange, TBARS (thiobarbituric acid reactive substances) and antioxidant enzyme assay. Both extracts showed H202 scavenging activity and inhibited lipid peroxidation in HDF cells irradiated by UVA. The extracts also recovered enzyme activity in the same cells.

Keywords

References

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