Case-control Study : Cerebral Blood Flow as Measured by TCD in Patients with Risk Factors for Stroke

TCD를 이용한 정상군과 중풍원인질환군의 혈류측정에 관한 비교연구

  • Heo, Jeong-Eun (Department of Internal Medicine, Hospital of Sames Oriental Medicine) ;
  • Kwon, Jung-Nam (Department of Internal Medicine, College of Oriental Medicine, Dong-Eui University) ;
  • Shin, Won-Tak (Department of Internal Medicine, Hospital of Sames Oriental Medicine) ;
  • Kim, Jong-Deuk (Department of Internal Medicine, College of Oriental Medicine, Dong-Eui University) ;
  • Lee, Sang-Hee (Department of Internal Medicine, College of Oriental Medicine, Dong-Eui University) ;
  • Son, Yeoun-Hui (Department of Internal Medicine, College of Oriental Medicine, Dong-Eui University) ;
  • Kim, Young-Kyun (Department of Internal Medicine, College of Oriental Medicine, Dong-Eui University)
  • 허정은 (삼세한방병원 한방내과) ;
  • 권정남 (동의대학교 한의과대학 심계내과학교실) ;
  • 신원탁 (삼세한방병원 한방내과) ;
  • 김종득 (동의대학교 한의과대학 심계내과학교실) ;
  • 이상희 (동의대학교 한의과대학 심계내과학교실) ;
  • 손연희 (동의대학교 한의과대학 심계내과학교실) ;
  • 김영균 (동의대학교 한의과대학 심계내과학교실)
  • Published : 2007.06.30

Abstract

Objectives : The purpose of this study was to evaluate the blood flow using doppler ultrasound of the MCA, ACA, PCA, BA, ICA in the patients with risk factor for stroke. Methods : 110 patients with risk factor for stroke were selected who had hypertension, diabetes mellitus, hyperlipidemia, or heart disease, as well as 89 healthy adults who did not have any symptoms of those diseases. To evaluate the blood flow, the Vs and Vm of the MCA, ACA, PCA, BA, and ICA in the two groups were measured. Result : In normal healthy adults, subjects showed a decrease in the Vs and Vm: with advancing in age, there was a significant difference in the Vs of MCA, PCA, BA, and ICA. There was a significant difference in the Vm of MCA, PCA, BA, and ICA. In normal healthy adults, females showed high velocities in all examined vessels. There was a significant difference in the Vs of BA. There was a significant difference in the Vm of BA, and ICA. There was a decrease in the Vs, and Vm of all examined vessels of patients with risk factors for stroke in comparison with normal healthy adults. There was no significant difference in the Vs. There was a significant difference in the Vm of MCA, ACA, and PCA. Results were the same between patients aged under 50 and total patients in the Vs and Vm of examined vessels. There were differences between patients aged over 50 and total patients in the Vs of MCA, PCA, BA and for patients aged over 50; patients with risk factor for stroke who had hypertension, diabetes mellitus, hyperlipidemia, or heat disease has higher Vs than healthy adults. Conclusions : There was a significant difference in the blood flow velocity between patients with risk factors for stroke and healthy adults. However, this result was different from results of comparison of TCD findings between patients and healthy individuals by age. Therefore, more detailed studies about aged patients are needed.

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