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Radiologic Assessment of Subsidence in Stand-Alone Cervical Polyetheretherketone (PEEK) Cage

  • Ha, Sung-Kon (Department of Neurosurgery, Korea University Medical Center Ansan Hospital) ;
  • Park, Jung-Yul (Department of Neurosurgery, Korea University Medical Center Ansan Hospital) ;
  • Kim, Se-Hoon (Department of Neurosurgery, Korea University Medical Center Ansan Hospital) ;
  • Lim, Dong-Jun (Department of Neurosurgery, Korea University Medical Center Ansan Hospital) ;
  • Kim, Sang-Dae (Department of Neurosurgery, Korea University Medical Center Ansan Hospital) ;
  • Lee, Sang-Kook (Department of Neurosurgery, Korea University Medical Center Ansan Hospital)
  • Published : 2008.12.31

Abstract

Objective : Aim of study was to find a proper method for assessing subsidence using a radiologic measurement following anterior cervical discectomy and fusion (ACDF) with stand-alone polyetheretherketone (PEEK), $Solis^{TM}$ cage. Methods : Forty-two patients who underwent ACDF with $Solis^{TM}$ cage were selected. With a minimum follow-up of 6 months, the retrospective investigation was conducted for 37 levels in 32 patients. Mean follow-up period was 18.9 months. Total intervertebral height (TIH) of two fused vertebral bodies was measured on digital radiographs with built-in software. Degree of subsidence (${\Delta}TIH$) was reflected by the difference between the immediate postoperative and follow-up TIH. Change of postoperative disc space height (CT-MR ${\Delta}TIH$) was reflected by the difference between TIH of the preoperative mid-sagittal 2D CT and that of the preoperative mid-sagittal T1-weighted MRI. Results : Compared to preoperative findings, postoperative disc height was increased in all cases and subsidence was observed only in 3 cases. For comparison of subsidence and non-subsidence group, TIH and CT-MR ${\Delta}TIH$ of each group were analyzed. There was no statistically significant difference in TIH and CT-MR ${\Delta}TIH$ between each group at 4 and 8 weeks, but a difference was observed at the last follow-up TIH (p=0.0497). Conclusion : ACDF with $Solis^{TM}$ cage was associated with relatively good radiologic long-term results. Fusion was achieved in 94.5% and subsidence occurred in 8.1% by the radiologic assessment. Statistical analysis reveals that the subsidence seen later than 8 weeks after surgery and the development of subsidence does not correlate statistically with the change of the postoperative disc space height.

Keywords

References

  1. Bagby GW : Arthrodesis by the distraction-compression method using a stainless steel implant. Orthopedics 11 : 931-934, 1988
  2. Banwart JC, Asher MA, Hassanein RS : Iliac crest bone graft harvest donor site morbidity. A statistical evaluation. Spine 20 : 1055-1060, 1995 https://doi.org/10.1097/00007632-199505000-00012
  3. Bartels RH, Donk RD, Feuth T : Subsidence of stand-alone cervical carbon fiber cages. Neurosurgery 58 : 502-508; discussion 502-508, 2006 https://doi.org/10.1227/01.NEU.0000197258.30821.50
  4. Brooke NS, Rorke AW, King AT, Gullan RW : Preliminary experience of carbon fibre cage prostheses for treatment of cervical spine disorders. Br J Neurosurg 11 : 221-227, 1997 https://doi.org/10.1080/02688699746285
  5. Caspar W, Barbier DD, Klara PM : Anterior cervical fusion and Caspar plate stabilization for cervical trauma. Neurosurgery 25 : 491-502, 1989 https://doi.org/10.1227/00006123-198910000-00001
  6. Chen D, Fay LA, Lok J, Yuan P, Edwards WT, Yuan HA : Increasing neuroforaminal volume by anterior interbody distraction in degenerative lumbar spine. Spine 20 : 74-79, 1995 https://doi.org/10.1097/00007632-199501000-00014
  7. Cloward RB : The anterior approach for removal of ruptured cervical disks. J Neurosurg 15 : 602-617, 1958 https://doi.org/10.3171/jns.1958.15.6.0602
  8. Colpan ME, Attar A, Sekerci Z, Tuna H, Egemen N : Cervical foraminal area and intervertebral height changes after titanium ring cage placement : preliminary results. J Clin Neurosci 13 : 228-232, 2006 https://doi.org/10.1016/j.jocn.2005.03.035
  9. Gercek E, Arlet V, Delisle J, Marchesi D : Subsidence of stand-alone cervical cages in anterior interbody fusion : warning. Eur Spine J 12 : 513-516, 2003 https://doi.org/10.1007/s00586-003-0539-6
  10. Kettler A, Wilke HJ, Claes L : Effects of neck movements on stability and subsidence in cervical interbody fusion: an in vitro study. J Neurosurg 94 (1 Suppl) : 97-107, 2001 https://doi.org/10.3171/jns.2001.94.1.0097
  11. Kulkarni AG, Hee HT, Wong HK : Solis cage (PEEK) for anterior cervical fusion : preliminary radiological results with emphasis on fusion and subsidence. Spine J 7 : 205-209, 2007 https://doi.org/10.1016/j.spinee.2006.03.002
  12. Majd ME, Vadhva M, Holt RT : Anterior cervical reconstruction using titanium cages with anterior plating. Spine 24 : 1604-1610, 1999 https://doi.org/10.1097/00007632-199908010-00016
  13. Murphy MA, Trimble MB, Piedmonte MR, Kalfas IH : Changes in the cervical foraminal area after anterior discectomy with and without a graft. Neurosurgery 34 : 93-96, 1994 https://doi.org/10.1227/00006123-199401000-00013
  14. Rosenorn J, Hansen EB, Rosenorn MA : Anterior cervical discectomy with and without fusion. A prospective study. J Neurosurg 59 : 252-255, 1983 https://doi.org/10.3171/jns.1983.59.2.0252
  15. Schmieder K, Wolzik-Grossmann M, Pechlivanis I, Engelhardt M, Scholz M, Harders A : Subsidence of the wing titanium cage after anterior cervical interbody fusion : 2-year follow-up study. J Neurosurg Spine 4 : 447-453, 2006 https://doi.org/10.3171/spi.2006.4.6.447
  16. Shad A, Leach JC, Teddy PJ, Cadoux-Hudson TA : Use of the Solis cage and local autologous bone graft for anterior cervical discectomy and fusion : early technical experience. J Neurosurg Spine 2 : 116- 122, 2005 https://doi.org/10.3171/spi.2005.2.2.0116
  17. Siddiqui AA, Jackowski A : Cage versus tricortical graft for cervical interbody fusion. A prospective randomised study. J Bone Joint Surg Br 85 : 1019-1025, 2003 https://doi.org/10.1302/0301-620X.85B7.13398
  18. Silber JS, Anderson DG, Daffner SD, Brislin BT, Leland JM, Hilibrand AS, et al : Donor site morbidity after anterior iliac crest bone harvest for single-level anterior cervical discectomy and fusion. Spine 28 : 134-139, 2003 https://doi.org/10.1097/00007632-200301150-00008
  19. Smith GW, Robinson RA : The treatment of certain cervical-spine disorders by anterior removal of the intervertebral disc and interbody fusion. J Bone Joint Surg Am 40A : 607-624, 1958
  20. van Jonbergen HP, Spruit M, Anderson PG, Pavlov PW : Anterior cervical interbody fusion with a titanium box cage : early radiological assessment of fusion and subsidence. Spine J 5 : 645-649; discussion 649, 2005 https://doi.org/10.1016/j.spinee.2005.07.007
  21. Wilke HJ, Kettler A, Goetz C, Claes L : Subsidence resulting from simulated postoperative neck movements : an in vitro investigation with a new cervical fusion cage. Spine 25 : 2762-2770, 2000 https://doi.org/10.1097/00007632-200011010-00008

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  12. Polyetheretherketone (PEEK) for medical applications vol.27, pp.7, 2008, https://doi.org/10.1007/s10856-016-5731-4
  13. An Outcome Study of Anterior Cervical Discectomy and Fusion among Iranian Population vol.2016, pp.None, 2016, https://doi.org/10.1155/2016/4654109
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  15. Titanium/Polyetheretherketone Cages for Cervical Arthrodesis with Degenerative and Traumatic Pathologies: Early Clinical Outcomes and Fusion Rates vol.8, pp.1, 2008, https://doi.org/10.1111/os.12221
  16. Stand-Alone Cages for Anterior Cervical Fusion: Are There No Problems? vol.13, pp.1, 2008, https://doi.org/10.14245/kjs.2016.13.1.13
  17. To Plate or Not to Plate after a Single- or Two-Level Anterior Cervical Discectomy: Fusion with Cage-Plate Construct or Stand-Alone Cage vol.11, pp.1, 2008, https://doi.org/10.4184/asj.2017.11.1.1
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  23. Subsidence after Anterior Cervical Interbody Fusion Using a Zero-Profile Device vol.5, pp.2, 2019, https://doi.org/10.21129/nerve.2019.5.2.33
  24. Comparison of stand-alone cage and cage-with-plate for monosegmental cervical fusion and impact of virtual reality in evaluating surgical results vol.191, pp.None, 2008, https://doi.org/10.1016/j.clineuro.2020.105685
  25. Short Plate with Screw Angle over 20 Degrees Improves the Radiologic Outcome in ACDF: Clinical Study vol.10, pp.9, 2008, https://doi.org/10.3390/jcm10092034
  26. Recent progress in 3D-printed polyaryletherketone (PAEK)-based high-performance polymeric implants for musculoskeletal reconstructions vol.36, pp.19, 2021, https://doi.org/10.1557/s43578-021-00231-4