Korean Journal of Otorhinolaryngology-Head and Neck Surgery

Korean Society of Otolaryngology-Head and Neck Surgery (대한이비인후과학회)
권호 표지

Diagnosis of Salivary Gland Function Using Oral Schirmer Test

구강 Schirmer 검사를 이용한 타액선 기능의 진단

Chu, Hyung-Ro;Kim, Chang-Hoon;Lee, Jong-Sun;Park, Soo-Kyung;Koh, Eun-Seok;Rho, Young-Soo
주형로;김창훈;이종선;박수경;고은석;노영수

  • Published : 2008.02.01
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Abstract

Background and Objectives：The accurate measure of salivary flow rate requires a variety of clinical and experimental protocols. Several methods have traditionally been used to collect and measure the whole mouth saliva. The objective of this study was to Subjects and Method：The control group consisted of 85 healthy patients, while another group consisted of 30 patients with salivary grand resection or post-head and neck iradiation and a third group of 30 patients who sufered from subjective xerostomia caused by other patho-logies. Oral Schirmer test was caried out in al subjects. The main outcome was the weted length after 5 minutes. Results：The mean saliva flow was 59.3± 16.99 mm/5 min in the control group, 47.0± ± 1.65 mm/ 5 min in the third group. The diferences between the control group and the other two groups were statistically diferent (p<0.01). A cut-off value 40 m/5 min showed sensitivity of 83.7% and specificity of 62.5%. Conclusion：The oral Schirmer test is valid and reliable for identifying subjects with xerostomia. (Korean J Otorhinolaryngol-Head Neck Surg 2008 ;51 :153-6)

Keywords

References

  1. Atkinson JC, Wu AJ. Salivary gland dysfunction: Causes, symptoms, treatment. J Am Dent Assoc 1994;125(4):409-16 https://doi.org/10.14219/jada.archive.1994.0059
  2. Locker D. Xerostomia in older adults: A longitudinal study. Gerodontology 1995;12(1):18-25 https://doi.org/10.1111/j.1741-2358.1995.tb00125.x
  3. Porter SR, Scully C, Hegarty AM. An update of the etiology and management of xerostomia. Oral Surg Oral Med Oral Pahol Oral Radiol Endod 2004;97(1):28-46 https://doi.org/10.1016/j.tripleo.2003.07.010
  4. Strahl RC, Welsh S, Streckfus CF. Salivary flow rates: A diagnostic aid in treatment planning geriatric patients. Clin Prev Dent 1990;12(4):10-2
  5. White KD. Salvation: A review and experimental investigation of major techniques. Psychophysiology 1977;14(2):203-12 https://doi.org/10.1111/j.1469-8986.1977.tb03379.x
  6. Navazesh M, Christensen CM. A comparison of whole mouth resting and stimulated salivary measurement procedures. J Dent Res 1982;61(10):1158-62 https://doi.org/10.1177/00220345820610100901
  7. Sanchez-Guerrero J, Aquirre-Garcia E, Perez-Dosal MR, Kraus A, Cardiel MH, Soto-Rojas AE. The wafer test: A semi-quantitative test to screen for xerostomia. Rheumatology (Oxford) 2002;41(4):381-9 https://doi.org/10.1093/rheumatology/41.4.381
  8. Lopez-Jornet P, Camacho-Alonso F, Bermejo-Fenoll A. A simple test for salivary gland hypofunction using Oral Schirmer's test. J Oral Pathol Med 2006;35(4):244-8 https://doi.org/10.1111/j.1600-0714.2006.00411.x
  9. Cassolato SF, Turnbull RS. Xerostomia: Clinical aspects and treatment. Gerodontology 2003;20(2):64-77 https://doi.org/10.1111/j.1741-2358.2003.00064.x
  10. Fox PC, Busch KA, Baum BJ. Subjective reports of xerostomia and objective measures of salivary gland performance. J Am Dent Assoc 1987;115(4):581-4 https://doi.org/10.1016/S0002-8177(87)54012-0
  11. Pai S, Ghezzi EM, Ship JA. Development of a visual analogue scale questionnaire for subjective assessment of salivary dysfunction. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2001;91(3):311-6 https://doi.org/10.1067/moe.2001.111551
  12. Dawes C. Physiologic factors affecting salivary flow rate, oral sugar clearance, and the sensation of dry mouth in man. J Dent Res 1987;66:648-53 https://doi.org/10.1177/00220345870660S107
  13. Davis CC, Marks JE. The use of the Schirmer tear test in evaluating mouth dryness. Dent Hyg 1986;60(3):116-9,129
  14. Rhodus NL, Bereuter J. Clinical evaluation of a commercially available oral moisturizer in relieving signs and symptoms of xerostomia in postirradiation head and neck cancer patients and patients with Sjogren,'s syndrome. J Otolaryngol 2000;29(1):28-34
  15. Warde P, Kroll B, O'Sullivan B, Aslanidis J, Tew-George E, Waldron J, et al. A phase II study of biotene in the treatment of postradiation xerostomia in patients with head and neck cancer. Support Care Cancer 2000;8(3):203-8 https://doi.org/10.1007/s005200050286
  16. Givens E Jr. Update on xerostomia: Current treatment modalities and future trends. Gen Dent 2006;54(2):99-101
  17. Vitolo JM, Baum BJ. The use of gene transfer for the protection and repair of salivary glands. Oral Dis 2002;8(4):183-91 https://doi.org/10.1034/j.1601-0825.2002.02865.x
  18. Joraku A, Sullivan CA, Yoo JJ, Atala A. Tissue engineering of functional salivary gland tissue. Laryngoscope 2005;115(2):244-248 https://doi.org/10.1097/01.mlg.0000154726.77915.cc
  19. Aframian DJ, David R, Ben-Bassat H, Shai E, Deutsch D, Baum BJ, et al. Characterization of murine autologous salivary gland cells: A model for use with an artificial salivary gland. Tissue Eng 2004;10(5-6):914-20 https://doi.org/10.1089/1076327041348518