The Prevalence of Asbestos Exposure-induced Pleural Thickening on Chest Radiograph in Repairing Shipyard Workers

수리조선업 근로자들의 단순흉부촬영에서 흉막 비후 유병률 - 석면 노출과 관련하여

Ye, Byeong-Jin;Kim, Jung-Il;Lee, Hyun-Jae;Kim, Ki-Nam;Lee, Ki-Nam;Jung, Kap-Yeol;Kim, Joon-Youn;Yun, Sung-Ho
예병진;김정일;이현재;김기남;이기남;정갑열;김준연;윤성호

  • Published : 2008.03.10

Abstract

Objectives: This study evaluated the prevalence of asbestos exposure-induced pleural thickening on chest radiograph in repairing shipyard workers. Methods: A total of 2,114 incumbent and retired workers in a shipyard underwent chest radiograph, questionnaire study, interview, and physical exam from 2005 to 2007. Finally, 1,702 workers were selected and classified into two groups according to asbestos exposure: exposure and non-exposure groups. The characteristics in the exposure group were investigated. Results: The prevalence of pleural thickening on chest radiograph was 5.2 % and 3.1 % in the exposure and non-exposure groups, respectively (p<0.05). In those aged 50 years or above, the prevalence was 17.6 % and 8.7 % in the exposure and non-exposure groups, respectively (p<0.05). The prevalence was 16.5 % and 30.2 % and the odds ratio was 2.34 (95% CI; 1.15-4.77) and 2.95 (95%CI; 1.08-8.07) in the workers with an exposure duration of 20-29 years and more than 30 years, respectively. The prevalence was higher when considering tuberculosis history. Conclusions: The prevalence was increased with increasing exposure duration was more than 20 years. The authors therefore suggest that this group should be followed up periodically by special program and that a longitudinal study with repairing shipyard workers as the cohort should be undertaken.

목적: 본 연구는 수리조선업 사업장의 석면 노출 근로자와 비노출 근로자의 단순흉부촬영 검사에서 흉막 비후 의 유병률 차이를 비교하고 석면 노출군의 특징을 확인하는 것을 목적으로 하였다. 방법: 한 수리조선소에 현재 근무하고 있거나 퇴직한 근로자 중 2005년부터 2007년까지 단순흉부촬영을 받았 던 근로자 1,701명(79.4%)을 대상으로 석면 노출 여부와 노출기간에 따른 흉막 비후의 유병률을 분석하였다. 결과: 흉막 비후 유병률은 석면 노출군에서 5.2%, 비노출군에서 3.1%를 보였으며(p<0.05), 특히 50대 이상 에서 석면 노출군 17.6%, 비노출군 8.7%로 큰 차이를 보였다(p<0.05). 결핵의 병력이 있거나 의심되는 근로자 들을 제외한 경우에도 유병률의 유의한 차이가 있었다. 20~29년간 석면에 노출된 경우 16.5%, 30년 이상인 경 우 30.8%로 흉막 비후 유병률이 매우 높았다. 석면 노출기간이 20~29년, 30년 이상일 경우 흉막 비후의 교차비 가 각각 2.34(95%CI; 1.15~4.77), 2.95(95%CI; 1.08~8.07)이었다. 결론: 20년 이상 석면에 노출된 경우 흉막 비후 위험도가 높아지므로 적극적인 의학적 감시와 연구가 필요하다 고 사료된다.

Keywords

References

  1. Brodkin CA, Rosenstock L. Asbestosis and Asbestos- Related Pleural Disease. In: Rosenstock L, Cullen MR, Brodkin CA, Redlich CA (eds). Textbook of Clinical Occupational and Environmental Medicine. second edition. Elsevier Saunders, Philadelphia, 2005. p371
  2. Frumkin H, Berlin J. Asbestos exposure and gastrointestinal malignancy review and meta-analysis. Am J Ind Med 1988;14(1):79-95 https://doi.org/10.1002/ajim.4700140110
  3. Maclure M. Asbestos and renal adenocarcinoma: a casecontrol study. Environ Res 1987;42(2):353-61 https://doi.org/10.1016/S0013-9351(87)80200-1
  4. Jung JY, Ahn HS, Kim JW, Kim KA, Yun IG, Kim HW, Choi YM, Song JS. A case of asbestosis, pleural effusion and lung cancer caused by long-term occupational asbestos exposure. Tuberc Respir Dis 1994;41(6):651-7.(Korean) https://doi.org/10.4046/trd.1994.41.6.651
  5. Kang SK, Ahn YS, Chung HK. Occupational cancer in Korea in the 1990s. Korean J Occup Environ Med 2001;13(4):351-9.(Korean)
  6. Ministry of Labor of Republic of Korea. White Page of Labor. Seoul. 2005. p192
  7. Jung SH, Kim HR, Koh SB, Yong SJ, Choi BS, Ahn YS, Park TI, Chung MJ, Kim YM, Song JS, Chung YK, Myung JP. Epidemiologic Characteristics Revealed with Malignant Mesothelioma Surveillance System in Korea. Korean J Occup Environ Med 2006;18(1):46-52.(Korean)
  8. Yoon DY, Kang JW, Lee HJ, Kim JI, Son JE, Jung KY, Kim JY, Roh MS. A case of lung cancer caused by long term asbestos exposure. Korean J Occup Environ Med 2004;16(4);499-507.(Korean)
  9. Kim KN, Kim JI Lee KN, Jung KY, Kim JY. Imaging findings among retired workers who were long-term exposed to asbestos. Korean J Occup Environ Med 2006;18(2):87-93.(Korean)
  10. International Labour Organization. Guidelines for the use of the ILO international classification of radiographs of pneumoconioses. Occuaptional Safety and Health Series 22, Rev. 80. Geneva. 1980
  11. Yun IG, Park CY, Lee WC, Lim Y, Kim KA. Epide-miological survey on the environment and health status in asbestos factories. Korean J Occup Environ Med 1993;5(1):137-51.(Korean)
  12. Kim JW, Ahn HS, Kim KA, Lim Y, Yun IG. The effect of pleural thickening on the impairment of pulmonary function in asbestos exposed workers. Tuberc Respir Dis 1995;42(6):923-33.(Korean) https://doi.org/10.4046/trd.1995.42.6.923
  13. Lilis R, Miller A, Godbold J, Chan E, Selikoff IJ. Radiographic abnormalities in asbestos insulators: effects of duration from onset of exposure and smoking. Relationships of dyspnea with parenchymal and pleural fibrosis. Am J Ind Med 1991;20(1):1-15 https://doi.org/10.1002/ajim.4700200102
  14. Epler GR. Clinical overview of occupational lung disease. Radiol Clin North Am 1992;30(6):1121-33
  15. Staples CA. Computed tomography in the evaluation of benign asbestos-related disorders. Radiol Clin North Am 1992;30:1191-207
  16. Roach HD, Davies GJ, Attanoos R, Crane M, Adams H, Phillips S. Asbestos: When the dust settles - an imaging review of asbestos-related disease. Radiographics 2002;22:S167-84 https://doi.org/10.1148/radiographics.22.suppl_1.g02oc10s167
  17. Paek DM, Paik NW, Choi JK, Son MA, Im JG, Lee WJ, Moon YH, Park JS, Choi BS. Prevalence of asbestosis in Korean asbestos industry. Korean J Occup Environ Med 1995;7(1):46-57.(Korean)
  18. Kurumatani N, Natori Y, Mizutani R, Kumagai S, Haruta M, Miura H, Yonemasu K. A historical cohort mortality study of workers exposed to asbestos in a refitting shipyard. Ind Health 1999;37(1):9-17 https://doi.org/10.2486/indhealth.37.9
  19. Puntoni R, Merlo F, Borsa L, Reggiardo G, Garrone E, Ceppi M. A historical cohort mortality study among shipyard workers in Genoa, Italy. Am J Ind Med 2001; 40(4):363-370 https://doi.org/10.1002/ajim.1110