References
- Lodish H, Berk A, Kaiser C, Krieger M. Integrating cells into tissues. In: Molecular Cell Biology. 6th ed. 2008; 801-46.
- Sadler TW. Prelaminar germ disc. Langman's Medical Embryology. 5th ed. 1985; 48-57.
- Thiery JP. Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer 2002; 2: 442-54. https://doi.org/10.1038/nrc822
- Thiery JP, Sleeman JP. Complex networks orchestrate epithelialmesenchymal transitions. Nat Rev Mol Cell Biol 2006; 7: 131-42. https://doi.org/10.1038/nrm1835
- Boyer B, Valles AM, Edme N. Induction and regulation of epithelial mesenchymal transitions. Biochem Pharmacol 2000; 60: 1091-9. https://doi.org/10.1016/S0006-2952(00)00427-5
- Kalluri R, Neilson EG. Epithelial-mesenchymal transition and its implication for fibrosis. J Clin Invest 2003; 112: 1776-84. https://doi.org/10.1172/JCI200320530
- Gofuku J, Shiozaki H, Tsujinaka T, et al. Expression of E-cadherin and alpha-catenin in patients with colorectal carcinoma. Correlation with cancer invasion and metastasis. Am J Clin Pathol 1999; 111: 29-37. https://doi.org/10.1093/ajcp/111.1.29
- Washington K, Chiappori A, Hamilton K, et al. Expression of betacatenin, alpha-catenin, and E-cadherin in Barrett's esophagus and esophageal adenocarcinomas. Mod Pathol 1998; 11: 805-13 https://doi.org/10.1038/sj.mp.4001852
- Oda T, Kanai Y, Oyama T, et al. E-cadherin gene mutations in human gastric carcinoma cell lines. Proc Natl Acad Sci USA 1994; 91: 1858-62. https://doi.org/10.1073/pnas.91.5.1858
- Lowy AM, Knight J, Groden J. Restoration of E-cadherin and betacatenin expression in pancreatic cancer cells inhibits growth by induction of apoptosis. Surgery 2002; 132: 141-8. https://doi.org/10.1067/msy.2002.125168
- Batlle E, Sancho E, Franci C, et al. The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumor cells. Nat Cell Biol 2000; 2: 84-9. https://doi.org/10.1038/35000034
- Cano A, Perez-Moreno MA, Rodrigo I, et al. The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat Cell Biol 2000; 2: 76-83. https://doi.org/10.1038/35000025
- Comijn J, Berx G, Vermassen P, et al. The two-handed e box binding zinc finger protein sip1 down-regulates e-cadherin and induces invasion. Mol Cell 2001; 7: 1267-78. https://doi.org/10.1016/S1097-2765(01)00260-X
- Hemavathy K, Ashraf SI, Ip YT. Snail/Slug family of repressors: slowly going into the fast lane of development and cancer. Gene 2000; 257: 1-12. https://doi.org/10.1016/S0378-1119(00)00371-1
- Peinado H, Olmeda D, Cano A. Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat Rev Cancer 2007; 7: 415-28. https://doi.org/10.1038/nrc2131
- Shioiri M, Shida T, Koda K, et al. Slug expression is an independent prognostic parameter for poor survival in colorectal carcinoma patients. Br J Cancer 2006; 94: 1816-22. https://doi.org/10.1038/sj.bjc.6603193
- Greene FL. Fleming ID AJCC cancer staging manual. 6th ed. New York: Springer-Verlag, 2002.
- Jethwa P, Naqvi M, Hardy R, et al. Overexpression of Slug is associated with malignant progression of esophageal adenocarcinoma. World J Gastroenterol 2008; 14: 1044-52. https://doi.org/10.3748/wjg.14.1044
- Kyo S, Sakaguchi J, Ohno S, et al. High Twist expression is involved in infiltrative endometrial cancer and affects patient survival. Hum Pathol 2006; 37: 431-8. https://doi.org/10.1016/j.humpath.2005.12.021
- Bates RC, Mercurio AM. The epithelial-mesenchymal transition (EMT) and colorectal cancer progression. Cancer Biol Ther 2005; 4: 365-70. https://doi.org/10.4161/cbt.4.4.1655
- Yang J, Mani SA, Donaher JL, et al. Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 2004; 117: 927-39. https://doi.org/10.1016/j.cell.2004.06.006
- Nieto MA, Sargent MG, Wilkinson DG, Cooke J. Control of cell behaviour during vertebrate development by slug, a zinc finger gene. Science 1994; 264: 835-9. https://doi.org/10.1126/science.7513443
- Hajra KM, Chen DY, Fearon ER. The SLUG zinc-finger protein represses E-cadherin in breast cancer. Cancer Res 2002; 62: 1613-8.
- Martin TA, Goyal A, Watkins G, Jiang W. Expression of the transcription factors Snail, Slug, and Twist and their clinical significance in human breast cancer. Ann Surg Oncol 2005; 12: 1-9. https://doi.org/10.1245/ASO.2005.10.907
- Uchikado Y, Natsugoe S, Okumura H, et al. Slug expression in the E-cadherin preserved tumors is related to prognosis in patients with esophageal squamous cell carcinoma. Clin Cancer Res 2005; 11: 1174-80.
- Garinis GA, Menounos PG, Spanakis NE, et al. Hypermethylation associated transcriptional silencing of E-cadherin in primary sporadic colorectal carcinomas. J Pathol 2002; 198: 442-9. https://doi.org/10.1002/path.1237
- Smits R, Ruiz P, Diaz-Cano S, et al. E-cadherin and adenomatous popyposis coli mutations are synergistic in intestinal tumor initiation in mice. Gastroenterology 2000; 119: 1045-53. https://doi.org/10.1053/gast.2000.18162