GC/MS Analyses of Volatile Constituents from Native Schizandra chinensis

자생 오미자나무의 정유성분 GC/MS 분석

Lim, Soon-Sung;Lee, Yeon-Sil;Han, Saem;Chung, Kyu-Hwan;Lee, Sang-Hyun;Shin, Kuk-Hyun
임순성;이연실;한샘;정규환;이상현;신국현

  • Published : 20081200

Abstract

To search for the new development of industrial application, chemical analysis of volatile constituents from native Schizandra chinensis was conducted by GC and GC/MS spectrometric analyses. The chemical composition of the volatile constituents from S. chinensis was confirmed by the aid of Wiley/NBS Library and RI indice searches. The major constituents were α-pinene (7.46%), β-pinene (30.66%), 1,8-cineole (4.81%), and 4-methyl-1-(1-methylethyl)-3-cyclohexene-1-ol (7.90%) from the stems, and camphene (10.05%), β-pinene (17.67%), sabinene (4.02%), l-limonene (4.04%), 1-methyl-4-(1-methylethyl)benzene (4.97%), linalyl acetate (7.86%), and linalool oxide (4.84%) from the roots. Among them, β-pinene is a major constituent in the stems and roots of native S. chinensis that presented possibilities for industrial applications.

오미자나무로부터 산업적 용도를 찾고자 정유성분을 GC와 GC/MS의 분석법에따라 분석하였다. 오미자나무의 줄기에는 α-pinene(7.46%), β-pinene(30.66%), 1,8-cineole(4.81%), 4-methyl-1-(1-methylethyl)-3-cyclohexene-1-ol(7.90%) 등의 성분함량이 높았고, 오미자나무 뿌리에는 camphene(10.05%), β-pinene(17.67%), sabinene(4.02%), l-limonene(4.04%), 1-methyl-4-(1-methylethyl)benzene(4.97%), linalyl acetate(7.86%), linalool oxide(4.84%) 등의 성분함량이 높았다. 자생 오미자나무 줄기 및 뿌리에 공통적으로 β-pinene의 정유성분이 함유되어 있었으며, 오미자나무 줄기 및 뿌리의 향기특성을 이용한 산업화가 가능하다고 본다.

Keywords

References

  1. An, R.B., S.H. Oh, G.S. Jeong, and Y.C. Kim. 2006. Gomisin J with protective effect against t-BHP-induced oxidative damage in HT22 cells from Schizandra chinensis. Nat. Prod. Sci. 12:134-137
  2. Ahn, D.K. 2003. Illustrated Book of Korean Medicinal Herbs, p. 804-805. Kyo-Hak Publishing Co. Ltd., Korea
  3. Ahn, K.M. 2007. The effect of aroma inhalation method using sweet orange essential oil on stress. J. Kor. Soc. Cosm. 13:1121-1129
  4. Baek, N.I., J.T. Han, E.M. Ahn, J.K. Park, S.W. Cho, S.G. Jeon, J.S. Jang, C.K. Kim, and S.Y. Choi. 2000. Isolation of anticonvulsant compounds from the fruits of Schizandra chinensis BAILL. J. Korean Soc. Appl. Biol. Chem. 43:72-77
  5. Baik, J., W.Y. Lee, J.Y. Kim, and C.H. Pak. 2002. Changes in essential oil contents and growth of Chrysanthemum boreale treated by uniconazole. J. Kor. Soc. Hort. Sci. 43:364-368
  6. Cho, Y.J., I.S. Ju, B.C. Kim, W.S. Lee, M.J. Kim, B.G. Lee, B.J. An, J.H. Kim, and O.J. Kwon. 2007. Biological activity of Omija (Schizandra chinensis Baillon) extracts. J. Korean Soc. Appl. Biol. Chem. 50:198-203
  7. Chung, Y.J. and W.S. Ahn. 1995. Collection identification and ex-situ field conservation of the aromatic plants in Korea. RDA J. Agr. Sci. 37:57-75
  8. Dai, H., N. Tan, J. Zhou, and Y. Yi. 2005. Chemical constituents in volatile oil of Schisandra chinensis. Zhongcaoyao 36:1309-1310
  9. Ha, B.J. 2006. Aromatherapy, p. 11-16. SooMoonSa Publishing. Korea
  10. Ikeya, Y., H. Taguchi, H. Mitsuhashi, S. Takeda, Y. Kase, and M. Aburada. 1988. A lignan from Schizandra chinensis. Phytochemistry 27:569-573 https://doi.org/10.1016/0031-9422(88)83143-1
  11. Kim, J.S. and S.Y. Choi. 2008. Physicochemical properties and antioxidative activities of Omija (Schizandra chinensis Baillon). Korean J. Food & Nutr. 21:35-42
  12. Kim, K.S., C.G. Park, and J.K. Bang. 2003. Varietal and yearly differences of lignan contents in fruits of collected lines of Schizandra chinensis Baillon. Korean J. Medicinal Crop Sci. 11:71-75
  13. Kim, K.S., J.S. Song, and J.K. Bang. 2000. Changes in volatile compounds of Schizandra chinensis fruits according to drying and extracting methods. Korean J. Medicinal Crop Sci. 8:49-57
  14. Kim, O.C. and H.J. Chang. 1994. Volatile compounds from Schizandra chinensis Baillon. Han'guk Nonghwa Hakhoechi 37:30-36
  15. Lee, J.H., S.C. Chi, S.H. Kim, Y.H. Shin, H.J. Park, and J.W. Choi. 2005. Preventive effect of a Schizandrin C derivative DDB-mixed preparation (DWP-04) against hepatotoxicity induced by carbon tetrachloride. Kor. J. Pharmacogn. 36:44-49
  16. Lee, S.H., Y.C. Lee, and S.K. Yoon. 2003. Isolation of the antimicrobial compounds from Omija (Schizandra chinensis) extract. Korean J. Food Sci. Technol. 35:483-487
  17. Li, H., X. Meng, Y. Wu, Y. Bao, and Y. Li. 2004. Analysis of essential oil from stems of Schisandra chinensis (Turcz.) Baill. Chemical Research in Chinese Universities 20:311-313
  18. Liapi, C., G. Anifantis, I. Chinou, A.P. Kourounakis, S. Theodosopoulos, and P. Galanopoulou. 2007. Antinociceptive properties of 1,8-cineole and $\beta$-pinene from the essential oil of Eucalyptus camaldulensis leaves in rodents. Planta Med. 73:1247-1254 https://doi.org/10.1055/s-2007-990224
  19. McLafferty, F.W. and D.B. Stauffer. 1989. The Wiley/NBS registry of mass spectral data. Wiley Interscience, New York, USA
  20. Park, H.J., M.S. Lee, S.C. Chi, K.T. Lee, Y.H. Shin, and J.W. Choi. 2005. Evaluation of a Schzandrin C derivative DDBmixed preparation (DWP-04) on acetaminophen detoxification enzyme system in the animal model. Kor. J. Pharmacogn. 36:81-87
  21. Park, J.H. 2004. Medicinal plants of Korea, p. 538-540. Shinil Books, Korea
  22. Qin, B., Z. Tian, and Z. Lou. 1988. Constituents of the volatile oil from the fruit of Schisandra chinensis. Yaoxue Tongbao 23:338-339
  23. Seo, H.K. and K.S. Park. 2003. A study on the effects of aroma inhalation method using Clarysage essential oil on stress in middle-aged women. Kor. J. Women Health Nurs. 9:61-69
  24. Shon, K. and K.S. Kim. 2003. Effect of pinching and short-day treatment for height, flowering, and essential oil content of potted Elsholtzia ciliate and E. splendens. Hort. Environ. Biotechnol. 44:939-946
  25. Shon, K., J.S. Song, Y.A. Chae, and K.S. Kim. 1998. The growth and essential oil of Elsholtzia ciliate (Thunb.) Hylander. Hort. Environ. Biotechnol. 39:809-813
  26. Shon, K., J.S. Song, Y.A. Chae, and K.S. Kim. 1999. The growth and analysis of essential oil of Elsholtzia splendens Nakai. Hort. Environ. Biotechnol. 40:271-275
  27. Sousa, O.V., M.S. Silvério, G. Del-Vechio-Vieira, F.C. Matheus, C.H. Yamamoto, and M.S. Alves. 2008. Antinociceptive and anti-inflammatory effects of the essential oil from Eremanthus erythropappus leaves. J. Pharm. Pharmacol. 60:771-777 https://doi.org/10.1211/jpp.60.6.0013
  28. Wagner, H., S. Bladt, and E.M. Zgainski. 1984. Plant Drug Analysis: A thin layer chromatography photo atlas. Springer-Verlag, New York, USA
  29. Wang, Y., J. Wang, H. You, and Y. Cu. 2001. Analysis of essential oil from seeds of Schisandra chinensis by GC-MS. Zhongguo Yaoxue Zazhi China 36:91-92
  30. Yook, C.S. 1999. Colored medicinal plants of Korea, p. 183. Academy Publishing Co., Korea
  31. Yoon, P.S. 2002. Hortus koreana, p. 627. JisikSanupSa Publishing Co., Korea
  32. Zhang, S. and S. Wu. 2007. The chemical component of essential oils of Schisandra and its pharmacologic action. Zhongyaocai 30:118-120
  33. Zhu, Y., K. Yan, J. Wu, and G. Tu. 1988. Assay of lignans of Schizandra chinensis in Sheng Mai San by high-performance liquid chromatography. J. Chromatogr. A 438:447-450 https://doi.org/10.1016/S0021-9673(00)90280-2