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Clinical manifestations patterns of allergic disease in Korean children under the age of 6 : multi-center study

다 기관 설문 조사를 통한 알레르기 질환의 연령별 임상 양상

  • Kim, Dong Il (Department of Pediatrics, College of Medicine, Soonchunhyang University) ;
  • Yang, Hyeon Jong (Department of Pediatrics, College of Medicine, Soonchunhyang University) ;
  • Park, Young Mean (Department of Pediatrics, College of Medicine, Konkuk University) ;
  • Rha, Yeong Ho (Department of Pediatrics, College of Medicine, Kyunghee University) ;
  • Choung, Ji Tai (Department of Pediatrics, College of Medicine, Korea University) ;
  • Pyun, Bok Yang (Department of Pediatrics, College of Medicine, Soonchunhyang University)
  • 김동일 (순천향대학교 의과대학 소아과학교실) ;
  • 양현종 (순천향대학교 의과대학 소아과학교실) ;
  • 박용민 (건국대학교 의과대학 소아과학교실) ;
  • 나영호 (경희대학교 의과대학 소아과학교실) ;
  • 정지태 (고려대학교 의과대학 소아과학교실) ;
  • 편복양 (순천향대학교 의과대학 소아과학교실)
  • Received : 2007.12.13
  • Accepted : 2007.01.12
  • Published : 2008.06.15

Abstract

Purpose : It is widely known that allergic diseases progress through an allergic march. However, there have not been any recent reports in Korea on how the diseases progress. Methods : Parents who visited one of the Pediatric Allergy Clinics of four university hospitals in Seoul with a child under the age of 6 years during the period from May 1-30, 2006 were asked to complete a questionnaire. Results : A total of 229 parents answered the questionnaire about their children, of which 122 were male and 107 were female. The most common allergic disease before 2 years of age was atopic dermatitis (79%). Meanwhile, in 2- to 4-year age group, allergic rhinitis (38%) and asthma (37%) were predominant. The most common allergic disease in the 4- to 6-year age group was asthma (72%), followed by allergic rhinitis (64%). Seventy-three percent of the children had a family history of allergic disease, most often in the fathers (39%). Among patients with allergic rhinitis, 50% had experienced asthma in their earlier days and 30% had experienced atopic dermatitis. In addition, 57% of the children with asthma had suffered from atopic dermatitis. Parents believed that asthma was the most serious allergic disease. Conclusion : In the present study, allergic disease showed a tendency to march from atopic dermatitis to asthma and then to allergic rhinitis. Early diagnosis and treatment of atopic dermatitis is, therefore, considered important for prevention of the allergic march.

목 적 : 알레르기 질환이 알레르기 행진의 임상 양상을 보이며 이를 이해하는 것이 예방에 중요 한 것은 널리 알려진 사실이다. 그러나 국내에서 알레르기 진행에 대한보고는 미미 한 실정이다. 방 법 : 2006년 5월 1일부터 30일 까지 서울에 위치한 4개 대학병원의 소아 알레르기 클리닉을 방문한 6세 미만 환아의 보호자들을 대상으로 설문 조사를 시행하였다. 결 과 : 총 229명의 환아 중 여자는 122명 남자는 107명이였다. 2세 이하에서는 아토피피부염(79%)이 가장 흔했고 뒤이어 천식(13%)과 알레르기비염(13%)의 순이었다. 2-4세에서는 알레르기비염(38%), 천식(37%), 아토피피부염(19%)의 순이었다. 4-6세에서는 천식(72%)이 가장 흔했으며 알레르기비염(64%)과 아토피피부염(21%)의 순이었다. 73%에서 가족력이 있었고 이중 아버지 알레르기 병력이 가장 흔했다. 알레르기비염을 가진 환아의 50%에서 천식, 30%에서 아토피피부염을 경험하였고 천식을 가진 환아의 57%가 과거에 아토피피부염을 가지는 알레르기 행진을 볼 수 있었다. 알레르기 질환의 심각도 조사에서 부모들은 영아기에는 천식을, 유아기에는 아토피피부염을 가장 심각한 알레르기 질환으로 생각하였다. 결 론 : 국내에서 6세 미만의 소아에서 알레르기 행진이 진행한다는 것을 알 수 있었다.

Keywords

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