Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Inhibitory Activity of IL-6 Production by Flavonoids and Phenolic Compounds from Geranium thunbergii

  • Published : 2008.03.31
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Abstract

Three flavonoids (1 - 3) and three phenolic compounds (4 - 6) were isolated from the whole plant of Geranium thunbergii Sieb. et Zucc (Geraniaceae). Their structures were determined by chemical and spectral analysis. These compounds were examined for the inhibitory activity of IL-6 production in $TNF-{\alpha}$ stimulated MG-63 cell. Among the isolated compounds, gallic acid (4) and gallic acid methyl ester (6) showed potent inhibitory activity.

Keywords

References

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