Relation between Health Examination Outcome and Intake of Soy Food and Isoflavone among Adult Male in Seoul

서울 거주 성인 남자의 대두식품 및 이소플라본 섭취와 각종 건강지표와의 관련성 분석

  • Lee, Min-June (Research Institute of Food and Nutritional Sciences, Yonsei University) ;
  • Sohn, Chun-Young (Dietetic Department Severance Hospitals, College of Yonsei University Medicine) ;
  • Kim, Ji-Hyang (Research Institute of Food and Nutritional Sciences, Yonsei University)
  • 이민준 (연세대학교 식품영양과학연구소) ;
  • 손춘영 (연세대학교 의과대학 세브란스병원 영양팀) ;
  • 김지향 (연세대학교 식품영양과학연구소)
  • Published : 2008.04.30

Abstract

This study was conducted to analyze the effect of isoflavone intake on prevention of chronic disease in middle and old aged man. In this study we used FFQ (Food frequency questionnaire) and the isoflavone intake level of the subjects was 25.10 mg per day. We divided the subjects into three group -high, medium, low isoflavone intake level- and investigated the relation among isoflavone intake level and clinical/anthropometric characteristics. The intake of isoflavone was inversely related with the body fat in male subjects. And we also divided the subjects into 2 groups with normal and abnormal clinical/anthropometric risk factor. The isoflavone intake level of the abnormal group with high TG, high WHR and high body fat was lower than the normal group. The main food source of isoflavone was soybean curd, bean sprout, soybean paste, soybean and soy milk, and we also investigated the relation between frequency of soybean food and anthropometric and clinical variables. The frequencies of soybean curd, soybean paste, soybean broth, soy milk, bean sprouts, peanuts, soybean and dambuk as well as intake of isoflavone were inversely correlated with some anthropometric and clinical variables such as blood pressure, TG, BMI, % body fat, and waist-hip ratio, whereas positively correlated with HDL cholesterol, muscle mass and bone density. We suggest that high consumption of soy products and isoflavone is associated with decreased blood lipid and body fat in middle and old aged man and might be useful for prevention cardiovascular diseases. From this study, we obtained valuable basic information on recommended isoflavone intake level and guidelines for the prevention of some chronic diseases/health problems.

본 연구에서 이소플라본의 섭취가 만성질환의 예방에 미치는 영향을 검토하기 위해 조사대상자를 이소플라본 섭취수준에 따라 세 그룹 (적게, 보통, 많이)으로 분류하여 각종 만성질환과 관련된 건장지표들의 차이를 분석하였으며, 연구결과를 요약하면 다음과 같다. 1) 연구 대상자인 성인 남자들의 평균 연령은 49세였고 헤모글로빈, 헤미토크리트, MCH 및 혈중 칼슘과 인의 평균 농도는 정상범위 내에 있었으며 혈당과 당화혈색소, 총콜레스테롤, HDL-콜레스테롤, 혈청 PSA 농도도 모두 정상범위에 들어있었다. 그러나 LDL-콜레스테롤과 중성지방은 기준을 약간 상회하는 수준이었다. 2) 조사대상자의 식이섭취상태를 간이조사법을 이용하여 분석한 결과 평균 에너지 섭취량은 1,967 kcal로 권장량에 미치지 못하였으나 그 밖의 단백빌, 칼슘, 인, 철분, 비타민 A, 티아민, 리보플라빈, 니아신, 비타민 C 등은 섭취기준을 상회하였다. 3) 조사대상자들의 하루 평균 이소플라본 섭취수준은 25.10 mg이었다. 이소플라본의 섭취분포를 살펴보면, 조사대상자의 1/4은 하루 이소플라본의 섭취수준이 12 mg 이하 수준이었으며, 중간 값은 20.77 mg이었고, 10%의 조사대상자는 하루 50mg 수준 이상의 이소플라본을 식사로부터 섭취하는 것으로 나타났다. 4) 이소플라본 섭취수준과 유의적인 관련성을 보여준 변수는 체지방율로, 이소플라본을 많이 섭취하는 사람들의 체지방율이 낮은 것으로 나타났다. 또한 그룹별 통계적 유의성은 없었으나, 이소플라본 섭취수준이 높은 사람들의 BMI와 허리-엉덩이 둘레의 비(WHR), 중성지방의 수준이 더 낮은 경향을 보여주었으며, HDL-콜레스테롤 수준이 높고, 골밀도 수치도 다소 높은 것으로 나타났다. 5) 고혈압${\cdot}$당뇨${\cdot}$고지혈증${\cdot}$골조소증${\cdot}$비만 등 건강문제를 갖고 있는 집단과 정상 집단으로 분류하여 집단 별 이소플라본의 평균 섭취수준을 비교한 결과, 혈중 중성지방 수준이 높은 집단, 복부비만을 나타내는 집단, 체지방률이 높은 집단의 경우 정상 집단에 비해 이소플라본 섭취수준이 유의적으로 낮았다. 6) 각종 만성질환 관련 지수와 이소플라본 섭취수준 및 각 급원식품의 섭취빈도 간의 상관성을 분석한 결과, 두부와 된장의 섭취빈도는 혈압과 음의 상관관계를, 콩국은 HDL-콜레스테롤과 양의 상관관계, 두유 및 이소플라본의 섭취수준은 혈청 중성지방과 음의 상관관계, 콩나물과 땅콩의 섭취빈도는 골밀도와 양의 상관관계를 보인 것으로 나타났다. 7) 콩의 섭취빈도가 높고 이소플라본 섭취수준이 높을수록 BMI가 낮아지는 것으로 나타났으며 근육량은 두유와 콩국의 섭취빈도 및 이소플라본 섭취수준과 양의 상관관계를 보였고, 체지방율은 된장, 청국장, 콩의 섭취빈도와 이소플라본 섭취수준과 음의 상관관계를, 엉덩이-허리둘레 비율은 된장의 섭취빈도와 음의 상관관계를 나타냈다.

Keywords

References

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