Case-control Study : Cerebral Blood Flow as Measured by Transcranial Doppler Ultrasonography(TCD) in Hypertensives

TCD를 이용한 고혈압환자군과 정상혈압군의 뇌혈류측정에 관한 비교연구

  • Heo, Jeong-Eun (Department of Internal Medicine, Hospital of Samse Oriental Medicine) ;
  • Kim, Young-Kyun (Department of Internal Medicine, College of Oriental Medicine, Dong-Eui University) ;
  • Kwon, Jung-Nam (Department of Internal Medicine, College of Oriental Medicine, Dong-Eui University) ;
  • Kim, Kyoung-Min (Department of Internal Medicine, College of Oriental Medicine, Dong-Eui University) ;
  • Kim, Bong-Hyun (Department of Oriental Rehabilitation Medicine, College of Oriental Medicine, Dong-Eui University) ;
  • Kim, Min-Kyu (Department of Oriental Rehabilitation Medicine, Hospital of Samse Oriental Medicine) ;
  • Kim, Jae-Kyu (Department of Internal Medicine, College of Oriental Medicine, Dong-Eui University) ;
  • Park, Sun-Mi (Department of Internal Medicine, Hospital of Samse Oriental Medicine)
  • 허정은 (삼세한방병원 내과학교실) ;
  • 김영균 (동의대학교 한의과대학 내과학교실) ;
  • 권정남 (동의대학교 한의과대학 내과학교실) ;
  • 김경민 (동의대학교 한의과대학 내과학교실) ;
  • 김봉현 (동의대학교 한의과대학 재활의학과) ;
  • 김민규 (삼세한방병원 재활의학과) ;
  • 김재규 (동의대학교 한의과대학 내과학교실) ;
  • 박선미 (삼세한방병원 내과학교실)
  • Published : 2008.12.31

Abstract

Objectives : The purpose of this study was to compare cerebral biood flow between hypertensives and normotensives using transcranial doppler ultrasonography (TCD). Methods : I investigated cerebral blood flow of 72 hypertensives and 127 normotensives. To evaluate the cerebral blood flow, I measured the systolic peak velocity(Vs) and mean How velocity (Vm) of the middle cerebral artery(MCA), anterior cerebral artery(ACA), posterior cerebral artery(PCA), basilar artery(BA), and internal carotid artery(ICA) in the two groups using TCD. Result : 1. There was a decrease in the Vs and Vm of all examined vessels of hypertensives in comparison with normotensives. There was a significant difference in the Vs of ACA and Vm of ACA, PCA, ICA. 2. In males, there was a decrease in the Vs of ACA, PCA, ICA and Vm of MCA, ACA, PCA, ICA of hypertensives in comparison with normotensives. However, there was no significant difference in the Vs or Vm of all examined vessels. 3. In females, there was a decrease in the Vs and Vm of all examined vessels of hypertensives in comparison with normotensives. There was a significant difference in the Vs of MCA, ACA and BA and Vm of ACA, PCA and BA. 4. In 30-49 year-olds, there was a decrease in the Vs and Vm of all examined vessels of hypertensives in comparison with normotensives. There was a significant difference in the Vs of ACA and Vm of ACA. 5. In 50-69 year-olds, there was a decrease in the Vs of ACA, PCA, BA, ICA and Vm of all examined vessels of hypertensives in comparison with normotensives. However, there was no significant difference in the Vs or Vm of all examined vessels. 6. In 70-89 vests old. there was a decrease in the Vs. Vm of PCA, BA, ICA of hypertensives in comparison with normotensives. But, there was no significant difference in the Vs, Vm of all examined vessels. Conclusions : There was a significant difference in the cerebral blood now velocity between hypertensives and normotcnsives. These results suggest that blood pressure has influence on cerebral blood flow.

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