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Contractile Activity of Goldfish Intestine Exposed to 18F Isotope

18F 동위원소 피폭에 의한 금붕어 장관 평활근의 수축활성

  • Moon, Gyeong-Hee (Department of Physics, Pukyong National University) ;
  • Ok, Chi-Il (Department of Physics, Pukyong National University) ;
  • Cho, Seung-Il (Department of Physics, Pukyong National University) ;
  • Lee, Jong-Kyu (Department of Physics, Pukyong National University) ;
  • Kil, Sang-Hyeong (Department of Nuclear Medicine, Pusan National University Hospital) ;
  • Seo, Won-Chan (Major of Materials Processing Engineering, Pukyong National University) ;
  • Lee, Byung-Woo (Major of Materials Processing Engineering, Pukyong National University) ;
  • Sohn, Hee-Young (Department of Biotechnology, Pukyong National University) ;
  • Go, Hye-Jin (Department of Biotechnology, Pukyong National University) ;
  • Park, Nam-Gyu (Department of Biotechnology, Pukyong National University)
  • Published : 2008.04.30

Abstract

Goldfish were exposed to radioactive isotope $^{18}F$, which is used for positron emission tomography (PET). $^{18}F$ is created when the oxygen in water combines with hydrogen on exposure to positrons accelerated by a cyclotron. The temporal change in intestine contractility was measured by physiograph after the exposure to $^{18}F$. The distance between the goldfish and 580 mCi of $^{18}F$ was approximately 4 cm and the exposure was for 4 hrs. The absorption level calculated from the distance, exposure time, and half-life of $^{18}F$ was approximately 2 Gy. The contractile activity of goldfish intestine was lowest on the first day and increased gradually to 100% of the control level by a period of between 5 and 36 days.

Keywords

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