Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Phytochemical Constituents of Schizonepeta tenuifolia Briquet

  • Lee, Il-Kyun (Natural Products Laboratory, College of Pharmacy, Sungkyunkwan University) ;
  • Kim, Min-Ah (Natural Products Laboratory, College of Pharmacy, Sungkyunkwan University) ;
  • Lee, Seung-Young (Natural Products Laboratory, College of Pharmacy, Sungkyunkwan University) ;
  • Hong, Jong-Ki (Phrmaceutical Analysis Laboratory, College of Pharmacy, Kyunghee University) ;
  • Lee, Jei-Hyun (College of Oriental Medicine, Dongguk University) ;
  • Lee, Kang-Ro (Natural Products Laboratory, College of Pharmacy, Sungkyunkwan University)
  • Published : 2008.06.30
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Abstract

Column chromatographic separation of the MeOH extract from the aerial parts of Schizonepeta tenuifolia Briquet led to the isolation of twelve terpenes (1 - 11 and 17), four phenolics (13 - 16) and a hexenyl glucoside (12). Their structures were determined by spectroscopic means to be (-)-pulegone (1), piperitenone (2), p-cymene-3,8-diol (3), schizonepetoside A (4), schizonepetoside C (5), (+)-spatulenol (6), ursolic acid (7), $2{\alpha}$,$3{\alpha}$,$24{\alpha}$,-trihydroxyolean-12en-28oic acid (8), $5{\alpha}$,$8{\alpha}$-epidioxyergosta-6,22-diol-$3{\beta}$-ol (9), stigmast-4-en-3-one (10), ${\beta}-sitosterol$ (11), (Z)-3-hexenyl-1-O-${\beta}$-D-glucopyranoside (12), rosmarinic acid (13), apigenin-7-O-${\beta}$-D-glucopyranoside (14), luteolin-7-O-${\beta}$-D-glucuronopyranoside (15), hesperidin (16) and trans-phytol (17). Compounds 2, 3, 8, 9 and 12 were for the first time isolated from S. tenuifolia Briq.

Keywords

References

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