Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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Phytochemical Constituents from the Aerial Parts of Paris verticillata

삿갓나물 지상부의 식물화학적 성분 연구

  • Lee, Kyu-Ha (Natural Products Laboratory, College of Pharmacy, Sungkyunkwan University) ;
  • Kim, Ki-Hyun (Natural Products Laboratory, College of Pharmacy, Sungkyunkwan University) ;
  • Lee, Il-Kyun (Natural Products Laboratory, College of Pharmacy, Sungkyunkwan University) ;
  • Choi, Sang-Un (Korea Research Institute of Chemical Technology) ;
  • Lee, Kang-Ro (Natural Products Laboratory, College of Pharmacy, Sungkyunkwan University)
  • 이규하 (성균관대학교 약학대학 천연물 약품화학 연구실) ;
  • 김기현 (성균관대학교 약학대학 천연물 약품화학 연구실) ;
  • 이일균 (성균관대학교 약학대학 천연물 약품화학 연구실) ;
  • 최상운 (성균관대학교 약학대학 천연물 약품화학 연구실, 화학연구소) ;
  • 이강노 (성균관대학교 약학대학 천연물 약품화학 연구실)
  • Published : 2008.06.30
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Abstract

Column chromatographic separation of the MeOH extract from the aerial parts of Paris verticillata led to the isolation of three phenolics, two terpene glucosides and two pyrrolidine alkaloids. Their structures were characterized to be methyl caffeate (1), 5-hydroxy pyrrolidin-2-one (2), vanillic acid (3), benzyl alcohol glucopyranoside (4), (6S, 9R)-roseoside (5), staphylionoside H (6) and 5-methoxy pyrrolidin-2-one (7) by spectroscopic means. The isolated compounds (1-7) were for the first time reported from this source. The isolated compounds were tested for their cytotoxicity against four human tumor cell lines by SRB method in vitro.

Keywords

References

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