The Journal of Pediatrics of Korean Medicine (대한한방소아과학회지)

The Association of Korean Oriental Pediatrics (대한한방소아과학회)
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Anti-allergic Effects of Cheonmaec-tang in RBL-2H3 Cell

천맥탕(天麥湯)이 항알러지 염증반응에 미치는 영향

  • Kim, Yong-Hyeon (Department of Internal Medicine, College of Oriental Medicine, Dongeui University) ;
  • Lee, Seung-Yeon (Department of Pediatrics, College of Oriental Medicine, Dongeui University) ;
  • Kim, Won-Il (Department of Internal Medicine, College of Oriental Medicine, Dongeui University)
  • 김용현 (동의대학교 한의과대학 내과학교실) ;
  • 이승연 (동의대학교 한의과대학 소아과학교실전대학교 한의과대학 소아과학교실) ;
  • 김원일 (동의대학교 한의과대학 내과학교실)
  • Published : 2008.04.30
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Abstract

Objectives The purpose of this study was to examine the anti allergic reaction with Cheonmaec-tang. Methods We examined Cell Viability, ${\beta}$-hexosaminidase, TNF-${\alpha}$, IL-4 secretion from RBL-2H3 cell after pretreatment with 2 ㎎/ml, 4 ㎎/ml of Cheonmaec-tang. Results We observed that Cheonmaec-tang is reduced to ${\beta}$-hexosaminidase, TNF-${\alpha}$, IL-4 secretion in RBL-2H3 cell. Conclusions These results indicate that Cheonmaec-tang has anti-histamic effect and controls TNF-${\alpha}$, IL-4 secretion on allergic reaction.

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