The Effects of Nelumbinis Rhizomatis Nodus on Blood Glucose and Serum Lipid Levels in Streptozotocin-Induced Diabetic Rats

연근(蓮根)이 Steptozotocin으로 유발된 당뇨병(糖尿病) 백서(白鼠)의 혈당(血糖) 및 혈중(血中) 지질(脂質)에 미치는 영향

  • Lee, Yu-Gyoung (Department of Pediatrics, College of Oriental Medicine, Dongshin University) ;
  • Chai, Jung-Won (Department of Pediatrics, College of Oriental Medicine, Dongshin University)
  • 이유경 (동신대학교 한의과대학 소아과학교실) ;
  • 채중원 (동신대학교 한의과대학 소아과학교실)
  • Published : 2008.08.31

Abstract

Objectives : This study was designed to investigate the effects of Nelumbinis Rhizomatis Nodus(NRN) on production levels of Blood Glucose and Serum Lipid Levels. Methods : This study is about changes of blood glucose levels, body weights, levels of food and water uptake, levels of total cholesterol in the body, triglyceride, Creatinine, and BUN production by NRN extract. Results : Treatment with NRN regulated blood glucose levels effectively, but treatment with NRN did not affect body weights, food and water uptake. In addition, treating with NRN also lowered levels of total cholesterol, which is important for diabetes, and also lowered levels of triglyceride, too. Serum Creatinine levels were not affected, but serum BUN levels were lowered by treating with NRN, which were elevated in diabetes. Conclusions : These results demonstrate that NRN is effective to treat DM level and also has anti-hyperlipidemic effect.

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