An Analysis of the Gyungokgo's Ingredients and a Comparison Study on Anti-oxidation Effects According to the Kinds of Extract

경옥고(瓊玉膏)의 성분 분석 및 추출물별 항산화(抗酸化) 효능 비교

  • Lee, So-Yeon (Dept. of Internal Medicine, College of Oriental Medicine, Daegu-Haany University) ;
  • Shin, Yoo-Jeong (Dept. of Internal Medicine, College of Oriental Medicine, Daegu-Haany University) ;
  • Park, Jong-Hyuk (Dept. of Internal Medicine, College of Oriental Medicine, Daegu-Haany University) ;
  • Kim, Seung-Mo (Dept. of Internal Medicine, College of Oriental Medicine, Daegu-Haany University) ;
  • Park, Chi-Sang (Dept. of Internal Medicine, College of Oriental Medicine, Daegu-Haany University)
  • 이소연 (대구한의대학교 한의과대학 내과학교실) ;
  • 신유정 (대구한의대학교 한의과대학 내과학교실) ;
  • 박종혁 (대구한의대학교 한의과대학 내과학교실) ;
  • 김승모 (대구한의대학교 한의과대학 내과학교실) ;
  • 박치상 (대구한의대학교 한의과대학 내과학교실)
  • Published : 2008.06.30

Abstract

Objectives : To estimate the value of the Gyungokgo as therapeutic agent preventing against aging with an analysis of the ingredients and the bio-activating effects by enzymologic methods. Methods : A quantitative analysis of general ingredients' of the Gyungokgo's extract was done first. The effects on electronic donating ability, SOD-like activity, nitric oxide inhibition, xanthine oxidase inhibition, whitening effect have been investigated in the physiological activity measurement of function experiment. Results : The contained hydrolyzed amino acid is Valine, Aspartic acid, Arginine, Isoleucine and the contained free amino acid is Arginine, Phenylalanine, Valine, Glycine. The derivative of free amino acid is Phosphoserine, Carnocine, ${\gammer}$-Aminoisobutyric acid. And the Gyungokgo contains 14 species of minerals, K>Na>Ca>Mg>Fe>Al>Mn. Then, to assure of the Gyungokgo's anti-oxidation, these following subjects -polyphenol, electronic donating ability, SOD-like activity, nitric oxide inhibition, xanthine oxidase inhibition, tyrosinase inhibation- are analyzed and show high activity especially the most in chloroform extracts, (every ingredients written by the order of high amount) Conclusions : The Gyungokgo contains many materials functioning as anti-oxidation, neurotransmitter, anti-fatigue and immune agent.

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