The Korea Journal of Herbology (대한본초학회지)

The Korea Association of Herbology (대한본초학회)
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A Study on the Antioxidative and Depigmentation Activities of the Ethanol Extract of Saururus Herba

삼백초(三白草) 에탄올추출물의 항산화능 및 피부 미백작용 연구

  • Park, Dae-Jung (Department of Herbal Prescription, College of Oriental Medicine, Sangji University) ;
  • Lee, Jang-Cheon (Department of Herbal Prescription, College of Oriental Medicine, Sangji University)
  • 박대중 (상지대학교 한의과대학 본초방제학교실) ;
  • 이장천 (상지대학교 한의과대학 본초방제학교실)
  • Published : 2008.06.30
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Abstract

Objectives : The purpose of this study is to investigate the etahnol extract of Saururus Herba and their dermal boiactivity properties related to cosmeceuticals such as depigmentation and radical scavenging effect. Methods : Using B16/F10 Melanin cells, we measured depigmentation effect of the etahnol extract of Saururus Herba. Antioxidant activities of the etahnol extract of Saururus Herba were determined by DPPH radical scavenging activity. Results : The etahnol extract of Saururus Herba showed considerable radical scavenging activity($SC_{50}$ : 25 ${\mu}g$/ml). Antioxidant activity is in a dose dependant manner. The etahnol extract of Saururus Herba down-regulated melanin synthesis effectively. B16 cells incubated with the etahnol extract of Saururus Herba showed reduces melanin formation and tyrosinase activity. The etahnol extract of Saururus Herba alone markedly suppressed melanin content and tyrosinase activity. Conclusions : These results suggest that the ethanol extract of Saururus Herba is a potent depigmentaion agent and it may be a candidate for antioxidant agent.

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