The Korea Journal of Herbology (대한본초학회지)

The Korea Association of Herbology (대한본초학회)
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Effects of Herbal-cheonggukjang on Serum Cholesterol Levels in Rats

생약초 청국장이 흰쥐의 혈중 콜레스테롤 함량에 미치는 영향

  • Kim, Hyung-Woo (Research Center of Industrial Accelerators) ;
  • Cho, Su-Jin (College of medicine, Korea University) ;
  • Kim, Bu-Yeo (School of Dentistry, Kyung Hee University) ;
  • Jung, Sun (College of Korean medicine, Dongshin University) ;
  • Park, Jung-Suk (Department of Complementary Alternative Therapy, Kwang-ju Womens University) ;
  • Lee, Sook-Young (Research center for Proteineous Materials, Chosun University) ;
  • Cho, Su-In (School of Oriental medicine, Pusan National University)
  • 김형우 (산업용가속기이용 생물연구센터) ;
  • 조수진 (고려대학교 의과대학) ;
  • 김부여 (경희대학교 치의학전문대학원) ;
  • 정선 (동신대학교 한의과대학) ;
  • 박정숙 (광주여자대학교 대체요법학과) ;
  • 이숙영 (조선대학교 단백질소재 연구센터) ;
  • 조수인 (부산대학교 한의학전문대학원)
  • Published : 2008.03.30
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Abstract

Ojectives : Cheonggukjang(natto) is known to have anti-hyperlipidemic action. This study was designed to investigate whether Herbal-cheonggukjang (HC, Herbal-natto) is more effective than cheonggukjang only, Methods : We investigated anti-hyperlipidemic effects of HC in hyperlipidemic rats induced by high-fat diet in terms of observation on levels of total cholesterol, HDL-cholesterol and triglyceride in serum. HC was made by cheonggukjang added Codonopsis Lanceolata, Houttuynia cordata and Lentinus edodes in indicated concetrations. Results : In this experiment, hyperlipidemic rats showed elevated levels of total cholesterol and triglyceride, and also showed lowered level of HDL-cholesterol. Oral administration of HC decreased levels of total cholesterol and triglyceride, Cheonggukjang(natto) did not affect levels of total cholesterol, HDL cholesterol and triglyceride. Conclusions : In these results, oral administration of HC decreased total cholesterol and triglyceride effectively. These results demonstrate that HC is useful to modulate cholesterol and triglyceride in serum.

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