Korean Journal of Family Medicine (가정의학회지)

The Korean Academy of Family Medicine (대한가정의학회)
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Effect of Barley on Variation of Blood Glucose and Lipid Metabolism

보리가 혈당 변화와 지질 대사에 미치는 단기영향

Yoo, Yeun-Seok;Lee, Kyung-Shik;Cho, Kyung-Hwan;Kim, Do-Hoon;Park, Chang-Hae;Lee, Seung-Hwan;Lee, Jong-Hyun
유연석;이경식;조경환;김도훈;박창해;이승환;이종현

  • Published : 20091000
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Abstract

Background: It is regarded that contemporary Korean diet, the combination of carbohydrates-based Korean traditional diet and the Western eating patterns, increases the vulnerability to chronic diseases such as coronary vascular disease, diabetes mellitus, and hypertension. Therefore, there is a rising interest in carbohydrate sources with low glycemic index; many researches have proven the medical benefits of low glycemic index diet. Barley has recently drawn attention and various benefits of barley, such as improvements of obesity and bowel function, have been suggested. It seems that the beta-glucan, a content of barley helps to lower blood sugar level. This study aimed to evaluate the advantages of barley consumption compared to wheat consumption in blood sugar and blood lipid profile levels. Methods: Twenty-four healthy Korea University students were randomly assigned to two groups: 12 of barley bread consumption group (treatment group) and 12 of wheat bread consumption group (control group). Both groups took bread on an empty stomach and the changes of their blood sugar and lipid levels were measured, compared, and analyzed every hour for four hours. Results: The blood sugar level one hour later in the barley bread consumption group was statistically low. In addition, the area under curve of the barley bread intake group was found to be statistically smaller. However, the blood lipid profiles between the two groups did not show meaningful difference. Conclusion: This study suggests that the consumption of food containing barley could bring various medical benefits to one's health by lowering blood sugar.

연구배경: 서구화된 식습관과 더불어 전통적으로 탄수화물을 주요 에너지원으로 하는 현대 우리나라의 식생활은 심혈관 질환, 당뇨병, 고혈압 등의 만성 생활습관병에 대한 감수성을 높인다고 생각된다. 이에 따라 낮은 당지수의 탄수화물 에너지원에 대한 관심이 높아지고 있고, 그 효과를 증명하는 연구가 많이 발표되고 있다. 최근 보리에 대해 관심도가 증가하고 있으며, 비만 개선, 대장 기능 개선 등의 여러 효과가 발표되고 있다. 또한 식이 섬유인 베타 글루칸을 함유하고 있어 혈당조절에 효과가 있는 것으로 보인다. 따라서 보리 섭취 후 혈당변화 및 혈중 지질 농도를 밀과 비교하여 보리가 갖는 이점을 평가 하고자 한다. 방법: 특별한 질환력이 없는 건강한 고려대학교 학생 24명을 대상으로 보리빵 식이군(시험군)과 밀가루 빵 식이군(대조군) 을 각각 1:1로 무작위 배정하였다. 공복 상태에서 각 군에 빵을 제공 하였고, 이 후 4시간 동안 혈당 변화와 혈중 지질 농도를 매 1시간 마다 측정하여 비교 하였다. 결과: 밀가루 빵 식이 군에 비해 보리빵 식이 군에서 식후 1시간 혈당이 통계적으로 유의하게 낮았으며, 혈당 곡선의 밑면적 역시 유의하게 작은 것을 알 수 있었다. 혈중 지질 농도는 두 군 간에 유의한 차이를 보이지 않았다. 결론: 보리를 함유한 음식물 섭취는 식후 혈당 개선을 통해 건강에 이로운 효과를 줄 것으로 보인다.

Keywords

References

  1. Kiessling SG, McClanahan KK, Omar HA. Obesity, hypertension, and mental health evaluation in adolescents: a comprehensive approach. Int J Adolesc Med Health 2008;20:5-15
  2. Ford ES, Williamson DF, Liu S. Weight change and diabetes incidence: findings from a national cohort of US adults. Am J Epidemiol 1997;146:214-22 https://doi.org/10.1093/oxfordjournals.aje.a009256
  3. Resnick HE, Valsania P, Halter JB, Lin X. Relation of weight gain and weight loss on subsequent diabetes risk in overweight adults. J Epidemiol Community Health 2000;54:596-602 https://doi.org/10.1136/jech.54.8.596
  4. Stapleton PA, James ME, Goodwill AG, Frisbee JC. Obesity and vascular dysfunction. Pathophysiology 2008;15:79-89 https://doi.org/10.1016/j.pathophys.2008.04.007
  5. Shiri R, Solovieva S, Husgafvel-Pursiainen K, Taimela S, Saarikoski LA, Huupponen R, et al. The association between obesity and the prevalence of low back pain in young adults: the Cardiovascular Risk in Young Finns Study. Am J Epidemiol 2008;167:1110-9 https://doi.org/10.1093/aje/kwn007
  6. Lajous M, Boutron-Ruault MC, Fabre A, Clavel-Chapelon F, Romieu I. Carbohydrate intake, glycemic index, glycemic load, and risk of postmenopausal breast cancer in a prospective study of French women. Am J Clin Nutr 2008;87:1384-91
  7. Kim WY, Kim JE, Choi YJ, Huh KB. Nutritional risk and metabolic syndrome in Korean type 2 diabetes mellitus. Asia Pac J Clin Nutr 2008;17 Suppl 1:47-51
  8. Connor H, Annan F, Bunn E, Frost G, McGough N, Sarwar T, et al. The implementation of nutritional advice for people with diabetes. Diabet Med 2003;20:786-807 https://doi.org/10.1046/j.1464-5491.2003.01104.x
  9. Mann J, Lean M, Toeller M, Slama G, Uusitupa M, Vessby B. Recommendations for the nutritional management of patients with diabetes mellitus. Eur J Clin Nutr 2000;54:353-5 https://doi.org/10.1038/sj.ejcn.1600962
  10. Sheard NF, Clark NG, Brand-Miller JC, Franz MJ, Pi-Sunyer FX, Mayer-Davis E, et al. Dietary carbohydrate (amount and type) in the prevention and management of diabetes: a statement by the American diabetes association. Diabetes Care 2004;27:2266-71 https://doi.org/10.2337/diacare.27.9.2266
  11. Ding EL, Malik VS. Convergence of obesity and high glycemic diet on compounding diabetes and cardiovascular risks in modernizing China: an emerging public health dilemma. Global Health 2008;4:4 https://doi.org/10.1186/1744-8603-4-4
  12. Salmeron J, Manson JE, Stampfer MJ, Colditz GA, Wing AL, Willett WC. Dietary fiber, glycemic load and risk of non-insulin-dependent diabetes mellitus in women. JAMA 1997;277:472-7 https://doi.org/10.1001/jama.277.6.472
  13. Liu S, Willett WC, Stampfer MJ, Hu FB, Franz M, Sampson L, et al. A prospective study of dietary glycemic load, carbohydrate intake and risk of coronary heart disease in US women. Am J Clin Nutr 2000;71:1455-61
  14. Frost G, Leeds AA, Dore CJ, Madeiros S, Brading S, Dornhorst A. Glycaemic index as a determinant of serum HDL-cholesterol concentration. Lancet 1999;353:1045-8 https://doi.org/10.1016/S0140-6736(98)07164-5
  15. Shimizu C, Kihara M, Aoe S, Araki S, Ito K, Hayashi K, et al. Effect of high beta-glucan barley on serum cholesterol concentrations and visceral fat area in Japanese men--a randomized, double-blinded, placebo-controlled trial. Plant Foods Hum Nutr 2008;63:21-5 https://doi.org/10.1007/s11130-007-0064-6
  16. Poppitt SD, van Drunen JD, McGill AT, Mulvey TB, Leahy FE. Supplementation of a high-carbohydrate breakfast with barley beta-glucan improves postprandial glycaemic response for meals but not beverages. Asia Pac J Clin Nutr 2007;16:16-24
  17. Behall KM, Scholfield DJ, Hallfrisch J. Diets containing barley significantly reduce lipids in mildly hypercholesterolemic men and women. Am J Clin Nutr 2004;80:1185-93
  18. Li J, Wang J, Kaneko T, Qin LQ, Sato A. Effects of fiber intake on the blood pressure, lipids, and heart rate in Goto Kakizaki rats. Nutrition 2004;20:1003-7 https://doi.org/10.1016/j.nut.2004.08.010
  19. Li J, Kaneko T, Qin LQ, Wang J, Wang Y. Effects of barley intake on glucose tolerance, lipid metabolism, and bowel function in women. Nutrition 2003;19:926-9 https://doi.org/10.1016/S0899-9007(03)00182-5
  20. Casiraghi MC, Garsetti M, Testolin G, Brighenti F. Post-prandial responses to cereal products enriched with barley beta-glucan. J Am Coll Nutr 2006;25:313-20 https://doi.org/10.1080/07315724.2006.10719541
  21. Warren JM, Henry CJ, Simonite V. Low glycemic index breakfasts and reduced food intake in preadolescent children. Pediatrics 2003;112:e414 https://doi.org/10.1542/peds.112.5.e414
  22. Brand-Miller J, Hayne S, Petocz P, Colagiuri S. Low-glycemic index diets in the management of diabetes: a meta-analysis of randomized controlled trials. Diabetes Care 2003;26:2261-7 https://doi.org/10.2337/diacare.26.8.2261
  23. Mendez MA, Covas MI, Marrugat J, Vila J, Schroder H. Glycemic load, glycemic index, and body mass index in Spanish adults. Am J Clin Nutr 2009;89:316-22 https://doi.org/10.3945/ajcn.2008.26444

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