Korean Journal of Family Medicine (가정의학회지)

The Korean Academy of Family Medicine (대한가정의학회)
권호 표지
DOI QR코드

DOI QR Code

The Relating Factor and Quality of Life of Overactive Bladder in Adults

성인의 과민성방광증후군의 관련 요인 및 삶의 질

Kim, Seun-Ah;Kim, Eun-Hae;Do, Hyun-Jin;Lym, Youl-Lee;Choi, Jae-Kyung;Joh, Hee-Kyung;Kweon, Hyuk-Jung;Cho, Dong-Yung;Kim, Tong-Wook
김선아;김은해;도현진;임열리;최재경;조희경;권혁중;조동영;김동욱

  • Published : 20091100
⟨ Previous Next ⟩

Abstract

Background: Overactive bladder syndrome (OAB) is a common disorder in primary care that affects negatively on the quality of life of outpatients. However, little information is available on related factors and the quality of life in adults with overactive bladder. The purpose of this study was to find related factors of overactive bladder and to measure the quality of life in adults with overactive bladder. Methods: Among the people who visited a hospital in Seoul and Chung-ju for a health examination or primary care between October 1 and December 31, 2008, we selected 327 participants over 20 years old. We measured their Overactive Bladder Questionnaire (OAB-q), took medical history and reviewed their demographic data. The relationship between OAB, other independent variables and health related quality of life (HRQL) were analyzed. Results: Of 327 respondents, the prevalence of OAB in adults was 38 (11.6%). The factors related to OAB were age (P = 0.007), history of prescription for congestive heart failure (P = 0.023), benign prostatic hyperplasia (BPH) (P = 0.002), and depression (P = 0.008). OAB was signifi cantly associated with BPH medication (P = 0.042; OR = 8.757) and depression medication (P = 0.005; OR = 9.977) in multivariable logistic regression analysis. In each T-test analysis, OAB decreased in HRQL. Conclusion: OAB is a common disorder in adults, history of BPH medication and depression medication is more common in OAB. The symptoms that were suggestive of OAB were affected negatively on the quality of life in adults. Effective health care polices and prompt management of OAB should be implemented.

연구배경: 과민성방광증후군(overactive bladder syndrome)은 일차 의료에서 흔하게 접할 수 있는 질환이며 과민성방광증후군의 증상은 삶의 질에 부정적 영향을 미치게 된다. 그러나 성인에서의 과민성방광증후군과 관련된 인자 및 삶의 질에 대한 정보가 미흡한 실정이다. 따라서 본 연구에서는 성인에서의 과민성방광증후군의 관련 인자를 찾고, 과민성방광증후군의 삶의 질을 측정하고자 한다. 방법: 2008년 10월 1일부터 12월 31일까지 서울 및 충주 일개 대학병원을 방문한 20세 이상의 환자 396명을 대상으로 인구학적 특성을 묻는 설문지와 Overactive Bladder Questionnaire (OAB-q)를 시행하였고, 최종적으로 설문 누락이나 통계 불가한 69명(17.4%)을 제외한 327명을 대상으로 과민성방광증후군의 관련 인자 및 삶의 질과의 연관성에 대하여 통계 분석하였다. 결과: 총 327명 중, 과민성방광증후군으로 진단된 수는 38(11.6%)명이었다. 과민성방광증후군은 연령대(P=0.007), 심부전증 약제 복용력(P=0.023), 전립선비대증 약제 복용력(P=0.002) 및 우울증 약제 복용력(P=0.008) 등과 관련 있는 것으로 나왔으며, 이를 연관 변수로 보정한 결과 전립선비대증 약제 복용력(P=0.042; OR=8.757) 및 우울증 약제 복용력(P=0.005; OR=9.977)과 연관성 있는 것으로 나왔다. 과민성방광증후군으로 진단된 군에서 정상인 군에 비하여 삶의 질이 확실히 감소함을 알 수 있었다. 결론: 성인에서 과민성방광증후군은 일반적으로 흔하게 접할 수 있는 질병이며, 전립선비대증 약제 복용력 및 우울증 약제 복용력이 있는 경우 더 흔하게 관찰되었고, 과민성방광증후군과 관련된 증상들로 인하여 삶의 질의 감소가 나타났다. 과민성방광증후군으로 고통 받는 환자들을 적절히 파악하고, 관련인자를 분석하여 예방책과 치료에 관심을 가져야 할 것이다.

Keywords

References

  1. Abrams P, Cardozo L, Fall M, Griffiths D, Rosier P, Ulmsten U, et al. The standardisation of terminology of lower urinary tract function: report from the Standardisation Sub-committee of the International Continence Society. Neurourol Urodyn 2002;21:167-78 https://doi.org/10.1002/nau.10052
  2. Kim UH, Kim YH, Kim ME. The prevalence and quality of life of overactive bladder and urinary incontinence in young woman. Korean J Urol 2004;45:543-50
  3. Milsom I, Abrams P, Cardozo L, Roberts RG, Thuroff J, Wein AJ. How widespread are the symptoms of an overactive bladder and how are they managed? A population-based prevalence study. BJU Int 2001;87:760-6 https://doi.org/10.1046/j.1464-410x.2001.02228.x
  4. Stewart WF, Van Rooyen JB, Cundiff GW, Abrams P, Herzog AR, Corey R, et al. Prevalence and burden of overactive bladder in the United States. World J Urol 2003;20:327-36
  5. Chen GD, Lin TL, Hu SW, Chen YC, Lin LY. Prevalence and correlation of urinary incontinence and overactive bladder in Taiwanese women. Neurourol Urodyn 2003;22:109-17 https://doi.org/10.1002/nau.10010
  6. Homma Y, Yamaguchi O, Hayashi K. An epidemiological survey of overactive bladder symptoms in Japan. BJU Int 2005;96:1314-8 https://doi.org/10.1111/j.1464-410X.2005.05835.x
  7. Moorthy P, Lapitan MC, Quek PL, Lim PH. Prevalence of overactive bladder in Asian men: an epidemiological survey. BJU int 2004;93:528-31 https://doi.org/10.1111/j.1464-410X.2003.04682.x
  8. Choo MS, Lee YS, Kim HY, Lee JB, Kwon DD, Lee T. The prevalence of overactive bladder in Korea [abstract]. Int Urogynecol J 2001;12:S169
  9. Kim UH, Kim JM, Kim YH, Jeon YS, Kim ME, Lee NK, et al. The prevalence of overactive bladder syndrome and urinary incontinence in young and middle aged women. J Korean Continence Soc 2003;7:9-14 https://doi.org/10.5213/jkcs.2003.7.1.9
  10. Matza LS, Thompson CL, Krasnow J, Brewster-Jordan J, Zyczynski T, Coyne KS. Test-retest reliability of four questionnaires for patients with overactive bladder: the overactive bladder questionnaire (OAB-q), patient perception of bladder condition (PPBC), urgency questionnaire (UQ), and the primary OAB symptom questionnaire (POSQ). Neurourol Urodyn 2005;24:215-25 https://doi.org/10.1002/nau.20110
  11. Choi JB. Voiding dysfunction in women: incontinence and overactive bladder. Korean J Fam Med 2009;30(3 Suppl): S127-32
  12. Cooyne KS, Margolis MK, Zyczynski T, Elinoff V, Roberts R. Validation of an OAB screener in a primary care patient population in the US. 34th Joint Meeting of the International Continence Society and the International UroGynecological Association; 2004 Aug 23-27; Paris, France. Bristol: The International Continence Society; 2004
  13. Cheung WW, Khan NH, Choi KK, Bluth MH, Vincent MT. Prevalence, evaluation and management of overactive bladder in primary care. BMC Fam Pract 2009;10:8 https://doi.org/10.1186/1471-2296-10-8
  14. Coyne KS, Payne C, Bhattacharyya SK, Revicki DA, Thompson C, Corey R, et al. The impact of urinary urgency and frequency on health-related quality of life in overactive bladder: results from a national community survey. Value Health 2004;7:455-63 https://doi.org/10.1111/j.1524-4733.2004.74008.x
  15. Wennberg AL, Molander U, Fall M, Edlund C, Peeker R, Milsom I. A longitudinal population-based survey of urinary incontinence, overactive bladder, and other lower urinary tract symptoms in women. Eur Urol 2009;55:783-91 https://doi.org/10.1016/j.eururo.2009.01.007
  16. Lee KS, Lee YS. Overactive bladder. Korean J Urol 2007;48:1191-208 https://doi.org/10.4111/kju.2007.48.12.1191
  17. Sampselle CM, Harlow SD, Skurnick J, Brubaker L, Bondarenko I. Urinary incontinence predictors and life impact in ethnically diverse perimenopausal women. Obstet Gynecol 2002;100:1230-8 https://doi.org/10.1016/S0029-7844(02)02241-X
  18. Hannestad YS, Rortveit G, Daltveit AK, Hunskaar S. Are smoking and other lifestyle factors associated with female urinary incontinence? The Norwegian EPINCONT Study. BJOG 2003;110:247-54 https://doi.org/10.1046/j.1471-0528.2003.02327.x
  19. Melville JL, Katon W, Delaney K, Newton K. Urinary incontinence in US women: a population-based study. Arch Intern Med 2005:165:537-42 https://doi.org/10.1001/archinte.165.5.537
  20. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, et al. The seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure: the JNC 7 report. JAMA 2003;289:2560–72 https://doi.org/10.1001/jama.289.19.2560
  21. Ekundayo OJ, Markland A, Lefante C, Sui X, Goode PS, Allman RM, et al. Association of diuretic use and overactive bladder syndrome in older adults: a propensity score analysis. Arch Gerontol Geriatr 2009:49:64-8 https://doi.org/10.1016/j.archger.2008.05.002
  22. Hunt SA, Abraham WT, Chin MH, Feldman AM, Francis GS, Ganiats TG, et al. ACC/AHA 2005 guideline update for the diagnosis and management of chronic heart failure in the adult: a report of the American college of cardiology/ American heart association task force on practice guidelines (writing committee to update the 2001 guidelines for the evaluation and management of heart failure): developed in collaboration with the American college of chest physicians and the international society for heart and lung transplantation: endorsed by the heart rhythm society. Circulation 2005;112: e154–235. https://doi.org/10.1161/CIRCULATIONAHA.105.167586
  23. Yamaguchi C, Sakakibara R, Uchiyama T, Yamamoto T, Ito T, Liu Z, et al. Overactive bladder in diabetes: a peripheral or central mechanism? Neurourol Urodyn 2007;26:807-13 https://doi.org/10.1002/nau.20404
  24. Stewart WF, Van Rooyen JB, Cundiff GW, Abrams P, Herzog AR, Corey R, et al. Prevalence and burden of overactive bladder in the United States. World J Urol 2003;20:327-36
  25. Melville JL, Walker E, Katon W, Lentz G, Miller J, Fenner D. Prevalence of comorbid psychiatric illness and its impact on symptom perception, quality of life, and functional status in women with urinary incontinence. Am J Obstet Gynecol 2002;187:80-7 https://doi.org/10.1067/mob.2002.124839
  26. Coyne K, Revicki D, Hunt T, Corey R, Stewart W, Bentkover J, et al. Psychometric validation of an overactive bladder symptom and health-related quality of life questionnaire: the OAB-q. Qual Life Res 2002;11:563-74 https://doi.org/10.1023/A:1016370925601
  27. Oh SJ, Ku JH, Choo MS, Yun JM, Kim DY, Park WH. Healthrelated quality of life and sexual function in women with stress urinary incontinence and overactive bladder. Int J Urol 2008;15:62-7 https://doi.org/10.1111/j.1442-2042.2007.01905.x

Cited by

  1. 일 지역 주민의 과민성방광 증상심각도 영향요인 vol.23, pp.1, 2009, https://doi.org/10.5953/jmjh.2016.23.1.39
  2. Sex Difference in Associations between Severity Level of Overactive Bladder and Perceived Stress, Depression in Korean Patients vol.44, pp.1, 2019, https://doi.org/10.21032/jhis.2019.44.1.14
  3. 중년기 과민성방광증후군 환자의 증상심각도, 스트레스가 우울에 미치는 융합 연구 vol.11, pp.12, 2009, https://doi.org/10.15207/jkcs.2020.11.12.419