Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
권호 표지

Antimicrobial Effect and Cytotoxicity of Chinensis Galla

오배자의 항균활성 및 세포독성에 미치는 영향

  • Kim, Seong-Jin (Department of Meridian & Acupoint, College of Oriental Medicine, Sangji University) ;
  • Yang, Ha-Young (Department of Oriental Pathology, College of Oriental Medicine, Sangji University) ;
  • Lee, Seon-Goo (Department of Oriental Pathology, College of Oriental Medicine, Sangji University)
  • 김성진 (상지대학교 한의과대학 경혈학교실) ;
  • 양하영 (상지대학교 한의과대학 병리학교실) ;
  • 이선구 (상지대학교 한의과대학 병리학교실)
  • Published : 2009.04.25
Download PDF
⟨ Previous Next ⟩

Abstract

Chinensis galla has been used as an multi-functional herb, such as anti-inflammatory, anti-virus, and antitumor agent. This study was performed to antimicrobial and cytotoxicity effect in vitro. The results were summarized as follows : Chinensis galla was antimicrobial effect on Staphylococcus aureus subsp. aureus, Bacillus cereus, Bacillus subtilis, Staphylococcus epidermidis. Chinensis galla was antimicrobial effect on Kocuria rhizophila, Corynebacterium ammoniagenes. The extracts of Chinensis galla exhibited cytotoxicity on human dermal fibroblast at $10\;{\mu}{\ell}$ but not at $5\;{\mu}{\ell}$, and the same results was known under a microscope. Accordingly the results show Chinensis galla could antimicrobial effect but exhibited cytotoxicity on human dermal fibroblast at high concentration and it needs more research.

Keywords

References

  1. 전국한의과대학 본초학 교수. 本草學. 영림사, pp 620-621, 1991
  2. 신민교. 原色臨床本草學. 영림출판사, pp 547-548, 1988
  3. 한국생물과학협회. 생물학사전. 아카데미서적, p 328, 1339, 1998
  4. Zaias, N. Pitted and ringed keratolysis. A review and update. J Am Acad Dermatol 7: 787-791, 1982 https://doi.org/10.1016/S0190-9622(82)70162-8
  5. Gill, K.A., Buckels, L.J. Pitted keratolysis. Arch Dermatol 98: 7-11, 1968 https://doi.org/10.1001/archderm.98.1.7
  6. 강원형. Atlas of skin disease. 한미의학, pp 205-207, 2006
  7. 안봉전. 오배자와 적포도과피 폴레페놀 분획물의 항균성 및 Glucosyltransferase 저해효과. Korean J. Postharvest SCI. Tecknol 8(2):217-223, 2001
  8. 최혜승, 김찬숙, 장대식, 유영범, 김이청, 이주석. 오배자 추출물의 어병세균에 대한 항균효능. J. Fish Pathol. 18(3):239-245, 2005
  9. 조민정, 홍석진, 최충호, 정성숙. 오배자, 파고지 추출물 함유치약이 치태형성 억제에 미치는 영향. J Korean Acad Dent Health 29(2):141-152, 2005
  10. 新文豐出版公司. 新編 中藥大辭典. 新文豐出版公司, pp 288-289, 1977
  11. 정재근, 김민지, 기혜영, 최미화, 서진종, 김선희, 박종태, 김명권, 김은선. 손 위생에 대한 식중독 원인균 실태조사. J. Fd Hyg. Safety 23(1):40-50, 2008
  12. Leung, D.Y.M. Atopic dermatitis : the skin as window into th pathogenesis of chronic allergic disease. J Allergy Clin Immunol 96: 301-318, 1995
  13. Nomura, I., Tanaka, K., Tomita, H., Katsunuma, T., Ohya, Y., Ikeda, N. et al. Evaluation of the staphylococcal exotoxins and their specific IgE in childhood atopic dermatitis. J Allergy Clin Immunol, 104: 441-446, 1999 https://doi.org/10.1016/S0091-6749(99)70390-8
  14. 임용순, 박천욱, 이철헌, 송원근. 소아 아토피 피부염에서 포도상구균 외독소 및 혈청 특이 IgE에 관한 연구. 대한피부과학회지 40(6):607-615, 2002
  15. Zaias, N., Talpin, D., Rebell, G. Pitted keratolysis. Arch Dermatol. 92: 151-154, 1965 https://doi.org/10.1001/archderm.1965.01600140039008
  16. Shelley, W.B., Shelley, E.D. Coexistent erythrasma, trichomycosis axillaris, and pitted keratolysis: an overlooked corynebacterial triad?. J Am Acad Dermatol, 7: 752-757, 1982 https://doi.org/10.1016/S0190-9622(82)80158-8
  17. Lee, J.H., Hyun, J.M. A study on the prevalence of pitted keratolysis. Korean J Mil Med, 17: 120-124, 1986