Journal of Korean Society of Environmental Engineers (대한환경공학회지)

Korean Society of Environmental Engineers (대한환경공학회)
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Occurrence of EDC/PPCPs in Influent and Effluent of a Wastewater Treatment Plant

하수처리장 유입.유출수 내 EDC/PPCPs의 발생 특성

  • Lee, Min-Ju (Department of Civil & Environmental Engineering, Chung-Ang University) ;
  • Ryu, Jae-Na (Department of Civil & Environmental Engineering, Chung-Ang University) ;
  • Oh, Je-Ill (Department of Civil & Environmental Engineering, Chung-Ang University) ;
  • Kim, Hyun-Bae (POSCO Engineering & Construction)
  • 이민주 (중앙대학교 건설환경공학과) ;
  • 류재나 (중앙대학교 건설환경공학과) ;
  • 오재일 (중앙대학교 건설환경공학과) ;
  • 김현배 ((주)포스코건설)
  • Received : 2009.02.17
  • Accepted : 2009.08.12
  • Published : 2009.09.30
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Abstract

This study investigated 31 selected EDCs(Endocrine Disrupting Compounds) and PPCPs(Pharmaceutical and Personal Care Products) in the influent and effluent of a wastewater treatment plant(WWTP) nearby Seoul metropolitan area. The chemical compounds of EDC/PPCPs detected from the plant influent sample include stimulant, X-ray contrast media and fire retardant. The total amount of each compound class were 59.67%, 20.20% and 9.00% respectively. However, in the effluent sample, the major micropolutants detected were oral beta-blocker(30.54%), fire retardant(20.49%), X-ray contrast media(18.17%). The EDC/PPCPs occurrence levels of this study were somewhat lower than previous domestic studies'. When compared to those of overseas, the values were even lower. Some pharmaceutical compound levels particularly measured in European studies were even several thousand times high. This study then compared PECs(Predicted Environmental Concentration) and MECs(Measured Environmental Concentration) of 9 selected pharmaceuticals compounds. The calculated PECs were substantially different with the MECs, while the occurrence order between the PECs and MECs in terms of concentrations of the compounds were similar.

서울 인근의 하수처리장에서 채취한 유입/유출수에 내포되어 있는 31개의 미량 EDC/PPCPs(내분비계장애물질/의 약 개인관리용품물질)의 발현 특성에 대한 조사 연구를 수행하였다. 유입수에서 검출된 EDC/PPCPs의 용도별 분류에 따른 총농도 관점의 발현 비율은 각성제(59.67%), X선 조영제(20.20%), 난연제(9.00%), 기타 등의 순으로 나타났으며, 유출수의 경우에는 베타 차단제(30.54%), 난연제(20.49%), X선 조영제(18.17%), 기타 등의 순으로 발현 빈도가 나타났다. 본 연구에서 검출된 대상 미량물질의 전반적인 농도 검출 범위는 다른 국내 선행연구에 비해 다소 낮은 것으로 나타났으며, 국외의 연구결과와 비교해서는 상당한 낮은 수준으로 검출되는 것으로 나타났다. 특히 유럽 지역의 연구결과와 비 교하면 일부 의약물질항목에 따라서는 수천 배의 농도차이를 보여주는 것으로 나타났다. 한편, 선택된 9개의 의약물질에 대해 유입수와 유출수의 예상환경농도(PEC)를 계산하고 실제 측정된 농도(MEC)와 비교한 결과 물질별 발현 농도 수치 관점에서는 큰 편차를 보였으나, 물질별 상대적 발현 빈도 순서 관점에서는 대체적으로 유사한 것으로 나타났다.

Keywords

References

  1. Ellis, J. B., "Pharmaceutical and personal care products (PPCPs) in urban receiving waters,” Environ. Pollu., 144, 184-189 (2006) https://doi.org/10.1016/j.envpol.2005.12.018
  2. Lindqvist, N., Tuhkanen, T., Kronberg, L., “Occurrence of acidic pharmaceuticals in raw and treated sewages and in receiving waters,” Water Res., 39, 2219-2228(2005) https://doi.org/10.1016/j.watres.2005.04.003
  3. Nakada, N., Tanishima, T., Shinohara, H., Kiri, K., and Takada, H., “Pharmaceutical chemicals and endocrine disrupters in municipal wastewater in Tokyo and their removal during activated sludge treatment,” Water Res., 40,. 3297-3303(2006) https://doi.org/10.1016/j.watres.2006.06.039
  4. Stasinakis, A. S., Gatidou, G., Mamais, D., Thomaidis, N. S., and Lekkas, T. D., “Occurrence and fate of endocrine disrupters in Greek sewage treatment plants,” Water Res., 42, 1796-1804(2008) https://doi.org/10.1016/j.watres.2007.11.003
  5. 국립환경과학원, “환경 중 의약물질 분석방법 연구 및 노출실태조사(II),” (2007)
  6. Ashton, D., Hilton, M., and Thomas, K. V., “Investigating the environmental transport of human pharmaceuticals to streams in the United Kingdom,” Sci. Total Environ., 333, 167-184(2004) https://doi.org/10.1016/j.scitotenv.2004.04.062
  7. Kolpin, D. W., Furlong, E. T., Meyer, M. T., Thurman, E. M., Zaugg, S. D., Barber, L. B., and Buxton, H. T.“, Pharmaceuticals, Hormones, and Other Organic Wastewater Contaminants in U. S. Streams, 1999-2000: A National Reconnaissance,” Environ. Sci. Technol., 36, 1202-1211(2002) https://doi.org/10.1021/es011055j
  8. 김주형, 박찬구, 김민영, 안승구, “LC/MS 를 이용한 물 환경내의잔류의약품 분석,” 한국환경분석학회지, 11(2), 99-108(2008a)
  9. Shane, A. S., Brett, J. V., J$\"{o}$rg, D., Eric, D., Erin, M. S., Gretchen, M. B., and Richard, C. P., State of Knowledge of Endocrine Disruptors and Pharmaceuticals in Drinking Water, Awwa Research Foundation, Denver, CO(2008)
  10. Vanderford, B. J., and Snyder, S. A., “Analysis of Pharmaceuticals in Water by Isotope Dilution Liquid Chromatography/Tandem Mass Spectrometry,” Environ. Sci. Technol., 40, 7312-7320(2006) https://doi.org/10.1021/es0613198
  11. Trenholm, R. A., Vanderford, B. J., and Snyder, S. A., “Analytical Methods for Measuring Endocrine Disruptors and Pharmaceuticals,” World Environmental and Water Resources Congress, American Society of Civil Engineers(2007)
  12. 김주형, 박찬구, 김민영, 안승구, “한강수계 상류지역의 동물용항생제 및 합성항균제 잔류실태 파악,” 한국환경분석학회지, 11(2), 109-118(2008b)
  13. Skadsen, J. M., Rice, B. L., and Meyering, D. J., “The occurrence and fate of pharmaceuticals, personal care products and endocrine disrupting compounds in a municipal water use cycle: A case study in the city of Ann Arbor.” City of Ann Arbor: Water Utilities and Fleis & VandenBrink Engineering, Inc(2004)
  14. Clara, M., Kreuzinger, N., Strenn, B., Gans, O., and Kroiss, H., “The solids retention time-a suitable design parameter to evaluate the capacity of wastewater treatment plants to remove micropollutants,” Water Res., 39, 97-106 (2005) https://doi.org/10.1016/j.watres.2004.08.036
  15. Tauxe-Wuersch, A., De Alencastro, L. F., Grandjean, D., and Tarradellas, J., “Occurrence of several acidic drugs in sewage treatment plants in Switzerland and risk assessment,” Water Res., 39, 1761-1772(2005) https://doi.org/10.1016/j.watres.2005.03.003
  16. G$\'{o}$mez, M. J., Mart nez Bueno, M. J., Lacorte, S., Fern ndez-Alba, A. R., and Ag era, A., “Pilot survey monitoring pharmaceuticals and related compounds in a sewage treatment plant located on the Mediterranean coast,” Chemosphere, 66, 993-1002(2007) https://doi.org/10.1016/j.chemosphere.2006.07.051
  17. Kim, S. D., Cho, J., Kim, I. S., Vanderford, B. J., and Snyder, S. A., “Occurrence and removal of pharmaceuticals and endocrine disruptors in South Korean surface, drinking, and waste waters,” Water Res., 41, 1013-1021(2007) https://doi.org/10.1016/j.watres.2006.06.034
  18. Glassmeyer, S. T., Furlong, E. T., Kolpin, D. W., Cahill, J. D., Zaugg, S. D., Werner, S. L., Meyer, M. T., and Kryak, D. D., “Transport of Chemical and Microbial Compounds from Known Wastewater Discharges: Potential for Use as Indicators of Human Fecal Contamination,” Environ. Sci. Technol., 39, 5157-5169(2005) https://doi.org/10.1021/es048120k
  19. Ternes, T. A., and Hirsch, R., “Occurrence and behavior of Xray contrast media in sewage facilities and the aquatic environment,” Environ. Sci. Technol., 34, 2741-2748(2000) https://doi.org/10.1021/es991118m
  20. Benotti, M. J., Trenholm, R. A., Vanderford, B. J., Holady, J. C., Stanford, B. D., and Snyder, S. A., “Pharmaceuticals and Endocrine Disrupting Compounds in U.S. Drinking Water,” Environ. Sci. Technol., 43, 597-603(2009) https://doi.org/10.1021/es801845a
  21. Ternes, T. A., and Joss, A., “Human pharmaceuticals, hormones and fragrances: the challenge of micropollutants in urban water management,” IWA Publising (2006)
  22. Jjemba, P. K., “Excretion and ecotoxicity of pharmaceutical and personal care products in the environment,” Ecotoxicol. Environ. Saf., 63, 113-130(2006) https://doi.org/10.1016/j.ecoenv.2004.11.011
  23. Katzung, B. G., “Basic & clinical pharmacology,” McGraw-Hill Medical(2007)
  24. Carballa, M., Omil, F., Lema, J. M., Llompart, M., Garcia-Jares, C., Rodr guez, I., G mez, M., and Ternes, T., “Behavior of pharmaceuticals, cosmetics and hormones in a sewage treatment plant,” Water Res., 38, 2918-2926(2004) https://doi.org/10.1016/j.watres.2004.03.029
  25. Andreozzi, R., Battilotti, M., Campanella, L., Lyberatos, G., Garric, J., and Paxeus, N. “Ecotoxicological assessments and removal technologies for pharmaceuticals in wastewaters,” Challenges in Environmental Risk Assessment and Modelling, 12-16(2002)
  26. Quintana, J. B., Weiss, S., and Reemtsma, T., “Pathways and metabolites of microbial degradation of selected acidic pharmaceutical and their occurrence in municipal wastewater treated by a membrane bioreactor,” Water Res., 39, 2654-2664(2005) https://doi.org/10.1016/j.watres.2005.04.068
  27. Ternes, T. A., Hirsch, R., Mueller, J., and Haberer, K., “Methods for the determination of neutral drugs as well as betablockers and $\beta$ 2-sympathomimetics in aqueous matrices using GC/MS and LC/MS/MS,” Fresenius J. Anal. Chem., 362, 329-340(1998) https://doi.org/10.1007/s002160051083
  28. 한국제약협회, “2007년 의약품등 생산실적표”, (2007)
  29. Kims online, available at http://www.kimsonline.co.kr/
  30. KFDA ezdrug, available at http://ezdrug.kfda.go.kr/