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The Influences of Immune Function and Respiratory System on Aerobic Exercise by Exposed Acute Hypobaric Hypoxic Environment.

급성 저압.저산소 노출에서의 유산소성 운동이 면역기능 및 호흡기계에 미치는 영향

  • Lee, Dong-Jun (Department of Physical education, Sport and Leisure Studies, Myongji University)
  • Published : 2009.06.30

Abstract

The purpose of this study was to investigate the influences of immune function and respiratory system on aerobic exercise of 75 %HRmax intensity in an exposed acute hypobaric hypoxic environment. The subjects were 20 male college students, 10 of which were soccer players (19.6${\pm}$0.8 yr, BMI 22.3${\pm}$1.0, V02max 56.5${\pm}$4.8 mljkgjmin) and 10 general students (22.2${\pm}$2.3 yr, BMI 22.7${\pm}$2.1, $VO_{2max}$ 50.5${\pm}$6.6 ml/kg/min). Items of measurement after exercise on level and high altitude were $O_{2}$, $CO_{2}$, ventilation (VE), respiratory frequency, respiratory quotient, RBC, MCV, MCH, MCHC, Hb, Hct, reticulocyte, WBC, neutrophil, lymphocyte, monocyte, basophil, and immunoglobulin (IgA, IgD, IgG, IgM). As the result of the verifying hypothesis, these results may suggest three new findings: first, to produce hypoxic ventilatory depression not only at level land but also at 3,000 m high altitude during 30 minute aerobics exercise of 75 %HRmax intensity, second to be more excellent for soccer players in adaptation and sensibility on response of respiratory system at high altitude, and third, to change each other by regular exercise habits or altitude in the monocyte.

본 연구에서는 저압.저산소환경의 노출을 시켜 30분간의 유산소성 자전거운동이 호흡기계 반응 및 면역기능의 응답에 미치는 영향을 검토하였다. 그 결과 몇 가지 지견을 도출해낼 수 있었다. 첫째로 75 $%HR_{max}$ 강도에서 30분간의 유산소성 운동 중에 저산소성 환기억제 또는 저하(hypoxic ventilatory depression or decline)라고 하는 현상은 평지뿐만이 아니라 3,000 m 고도에서도 나타나고 있고, 둘째 호흡기계의 반응은 축구선들이 특히 고소에서 적응과 감수성이 우수하다고 할 수 있으며, 셋째 면역기능의 항목인 단구(monocyte)는 운동습관의 유무 및 3,000 m의 고도에 따라 서로 다른 양상(상호작용)으로 변화를 하고 있다고 할 수 있다.

Keywords

References

  1. Berguland, B., S. J. Fleck, J. T. Kearney, and L. Wide. 1992. Serum erythropoietin in athletes at moderate altitude. Scand. J. Med. Sci. Sports 2, 21-25
  2. Brooks, G. A. and T. D. Fahey. 1984. Exercise Physiology. pp. 471-502, John Wiley & Sons, New York
  3. Burri, P. H. and E. R. Weibel. 1971. Morphometric estimation of pulmonary diffusion capacity; II Effect of environmental PO2 on the growing lung. Respir. Physiol. 11, 247-264 https://doi.org/10.1016/0034-5687(71)90028-4
  4. Daniels, J. and N. Oldridge. 1970. The effects of alternated exposure to altitude and sea level on world-class middle-distance runners. Med. Sci. Sports Exerc. 2, 107-112
  5. Frisancho, A. R. 1979. Human adaptation; a functional interpretation. The C.V. Mosby Co. St., Louis
  6. Gabriel, H., G. Rothe, M. Korpys, G. Schmitz, and W. Kindermann. 1997. Enhanced expression of HLA-DR, Fcgamma receptor 1 (CD64) and leukocyte common antigen (CD45) indicate activation of monocytes in regenerative training periods of endurance athletes. Int. J. Sports Med. 18, 136-141 https://doi.org/10.1055/s-2007-972609
  7. Gale, G. E., J. R. Torre-Bueno, R. E. Moon, H. A. Saltzman, and P. D. Wagner. 1985. Ventilation perfusion inequality in normal humans during exercise at sea level and simulated altitude. J. Appl. Physiol. 58, 978-988
  8. Jin, Y. S., M. J. Kim, J. Y. Park, K. S. Kim, J. T. Park, and Y. K. Kim. 1998. The effects of exercise pattern on acute response of T lymphocyte and natural killer cell: to search a immunological threshold around AT level. J. Kor. sports med. 16, 259-269
  9. Jung, D. S., J. K. Lee, Y. S. Kim, B. J. Park, B. J. Sung, J. R. Yoon, N. H. Cho, and I. S. Oh. 2004. Effects of intermittent normobaric hypoxia on blood variables and cardiovascular endurance performance during a period of endurance training. Korean J. Sport Sci. 15, 60-71
  10. Kim, K. J., J. O. Jin, and S. K. Lim. 1994. Aerobic capacities of elite female marathoners after three weeks of training at 1896m altitude. J. Kor. sports med. 12, 327-343
  11. Kim, K. J., K. T. Kim, B. H. Suh, X. Wen, and B. Yang. 1996. Change of physiological indicators in relation to the adaptation of altitude training of marathoners. Exer. Sci. 5, 37-50
  12. Klausen, T., U. Ghisler, T. Mohr, and N. Fogh-Andersen. 1992. Erythropoietin, 2,3 diphosphoglycerate and plasma volume during moderate-altitude training. Scand. J. Med. Sci. Sports 2, 16-20
  13. Kwak, Y. S., C. W. Kim, and Y. H. Paik. 2007. Immunological aspects of contemporary exercise. J. Life Science 17, 1166-1171 https://doi.org/10.5352/JLS.2007.17.8.1166
  14. Lee, E. J. and S. Sunoo. 2006. Effect of the different type of short-term hypobaric hypoxic training on aerobic exercise performance and blood variables and ACE gene polymorphism in relation to high altitude performance. The Korean J. Exer. Nutr. 10, 153-161
  15. Lee, J. K. and J. H. Kim. 2003. The effects of altitude training on $VO_2{max}$, anaerobic threshold, blood components and immune substrates in elite alpine skiers. Exer. Sci. 12, 357-366
  16. Lewicki, R., H. Tchorzewski, A. Denys, M. Kowalska, and A. Goilnska. 1987. Effect of physical exercise on some parameters of immunity in conditioned sportsman. Int. J. Sports Med. 8, 309-314 https://doi.org/10.1055/s-2008-1025675
  17. Mairbaurl, H. 1994. Red blood cell function in hypoxia at altitude and exercise. Int. J. Sports Med. 15, 51-63 https://doi.org/10.1055/s-2007-1021020
  18. Miyamura, M. 2001. ventilatory response in hypoxic environment. Japan J. Heal. Phys. Educ. Rec. 51, 281-285
  19. Pedersen, B. K., M. Kappel, M. Klokker, H. B. Nielsen, and N. H. Secher. 1994. The immune system during exposure to extreme physiologic condition. Int. J. Sports Med. 15, 116-121 https://doi.org/10.1055/s-2007-1021031
  20. Pedersen, B. K., N. Tvede, and L. D. Christensen. 1989. Natural killer cell activity in peripheral blood of highly trained and untrained persons. Int. J. Sports Med. 10, 129-131 https://doi.org/10.1055/s-2007-1024888
  21. Rodriguez, F, A., J. L. Ventura, M. Casas, H. Casas, T. Pages, R. Rama, A. Ricart, L. Palacios, and G. Viscor. 2000. Erythropoietin acute reaction and haematological adaptations to short, intermittent hypobaric hypoxia. Eur. J. Appl. Physiol. 82, 170-177 https://doi.org/10.1007/s004210050669
  22. Schoene, R. B., R. C. Roach, P. H. Hackett, J. R. Sutton, A. Cymerman, and C. S. Houston. 1990. Operation Everest II: ventilatory adaptation during gradual decompression to extreme altitude. Med. Sci. Sports Exerc. 22, 804-810 https://doi.org/10.1249/00005768-199012000-00012
  23. Sunoo, S. and K. S. Hwang. 2004. Effects of chronic intermittent hypobaric hypoxic training on cardiopulmonary function and oxygen transporting capacity in trained athletes. The Korean J. Phys. Edu. 43, 441-455
  24. Tatsumi, K., C. K. Pickett, and J. V. Weil. 1992. Effects of haloperidol and domperidone on ventilatory roll off during sustained hypoxisa in cats. J. Appl. Physiol. 72, 1945-1952
  25. Terrados, N. 1992. Altitude training and muscular metabolism. Int. J. Sports Med. 13, S206-S209 https://doi.org/10.1055/s-2007-1024641
  26. Vizek, M., C. K. Pickett, and J. V. Weil. 1987. Biphasic ventilatory response of adult cats to sustained hypoxia has central origin. J. Appl. Physiol. 63, 1658-1664
  27. Vogt, M., A. Puntschart, J. Flier, C. Geiser, R. Zuleger, and H. Hoppeler. 2001. Molecular adaptations in human skeletal muscle to endurance training under simulated hypoxic conditions. J. Appl. Physiol. 91, 173-182
  28. Ward, M. P., J. S. Milledges, and J. B. West. 1989. High altitude medicine and physiology. Chanpman and Hall Medical, London
  29. West, J. B. 1983. Climbing Mt Everest without supplementary oxygen-an analysis of maximal exercise during extreame hypoxia. Respir. Physiol. 52, 265-279 https://doi.org/10.1016/0034-5687(83)90085-3
  30. Wilmore, J. H. and D. L. Costill. 1994. Physiology of sport and exercise(Exercise in hypobaric, hyperbaric, and microgravity environments), Human Kinetics, IL, Champaign
  31. Yoon, S. J, J. C. Lee, Y. H. Byun, and J. M. You. 2005. Anaerobic capacity and blood lactate concentration at acute exposure hypoxia and normoxia. J. Sport Leis. Stu. 23, 367-377

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