The Journal of Korean Physical Therapy

The Korean Society of Physical Therapy (대한물리치료학회)
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Cortical Activation in the Human Brain induced by Transcranial Direct Current Stimulation

경두개 직류전류 자극이 대뇌피질의 뇌 활성도에 미치는 영향

  • Kwon, Yong-Hyun (Department of Physical Therapy, Yeungnam College of Science & Technology) ;
  • Kim, Chung-Sun (Department of Physical Therapy, College of Rehabilitation Science, Daegu University) ;
  • Jang, Sung-Ho (Department of Physical Medicine and Rehabilitation, Yeungnam University)
  • 권용현 (영남이공대학 물리치료학과) ;
  • 김중선 (대구대학교 재활과학대학 물리치료학과) ;
  • 장성호 (영남대학교 의과대학 재활의학교실)
  • Received : 2009.10.07
  • Accepted : 2009.12.15
  • Published : 2009.12.25
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Abstract

Purpose: Recently, neurostimulation studies involving manipulation of cortical excitability of the human brain have been increasingly attempted. We investigated whether transcranial direct current stimulation (tDCS) applied to the underlying cerebral cortex, directly induces cortical activation during fMRI scanning. Methods: We recently recruited five healthy subjects without a neurological or psychiatric history and who were right-handed, as verified by the modified Edinburg Handedness Inventory. fMRI was done while constant anodal tDCS was delivered to the underlying SM1 area?? immediately after the pre-stimulation for eighteen minutes. Results: Group analysis yielded an averaged map that showed that the SM1 area and the superior parietal cortex in the ipsilateral hemisphere were activated. The voxel size and peak intensity were, respectively, 82 and 5.22 in the SM1, and 85 and 5.77 in the superior parietal cortex. Conclusion: Cortical activation can be induced by constant anodal tDCS of the underlying motor cortex. This suggests that tDCS may be an effective therapeutic device for enhancing? physical motor function by modulating neural excitability of the motor cortex.

Keywords

References

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