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Systemic Review on Complementary and Alternative Medicine for Breast Cancer

유방암의 보완대체의학적 치료에 관한 연구

  • Park, Young-Ae (Dept. of Oriental Obstetric & Gynecology, college of Oriental Medicine, DaeguHaany University) ;
  • Kim, Dong-Chul (Dept. of Oriental Obstetric & Gynecology, college of Oriental Medicine, DaeguHaany University)
  • 박영애 (대구한의대학교 한의과대학 부인과 교실) ;
  • 김동철 (대구한의대학교 한의과대학 부인과 교실)
  • Published : 2009.08.31

Abstract

Purpose: The aim of this study was to review systemically journals on the studies for Complementary and Alternative Medicine in the treatment of breast cancer. Methods: Through medical websites, foreign clinical literatures about complementary and alternative medicines of breast cancer were searched. The cite used was http://www.Pubmed.gov. And then they were divided into three groups. Medication, Non-medication therapies and questionnaire reports. Results: 1. We researched 23 papers about herb medicines. Most of papers were about single herb and there were rarely about mixed composition. And there were papers about Ocimum gratissimum, elliptilimba, seeds of Livistona chinensis, golden feverfew which were not commonly used in Korea. 2. We researched 16 papers about acupuncture. Acupuncture had a possitive effect on such symptoms like flushing, nausea and vomitting and pain on upper limb caused by anticancer therapy or tamoxifen or surgery. 3. We researched 36 papers about questionnaire study. Most were about research for women who diagnosed as breast cancer or women after breast cancer surgery. Subjects were about proportion of using CAM, purpose of using it, most popular CAM therapy, satisfaction degree, and relation with age, aducation and social position. And most conclusion were that patient-doctor communication was needed. Conclusion: Afterwards we have to focus on realisitic clinical studies about breast cancer patients, especially postsurgery and people who takes anticancer therapy. And we have to be interest in acupuncture therapy on breast cancer patients.

Keywords

References

  1. 김혜영 등. 유방암 생존자의 삶의 질, 성기능 및 우울: 성생활 집단과 비성생활 집단 간의 비교. 종양간호학회지. 2008;8(2):77-85.
  2. Korea Central Cancer Registry. 2002 Annual Report of the Korea Central Cancer Registry. Seoul: Ministry of health and Welfare. 2003.
  3. 김영구. 비뇨기계 질환의 보완대체 치료. Urotrend. 2002;7(1):6-10.
  4. 송희완. 종합병원에 입원한 암 환자들의 보완대체의학의 사용. 한국보건복지학회지. 2007;7:37-60.
  5. 이정희, 유동열. 2000년 이후 국내 유방암에 대한 한약물의 최신 연구 경향 메타분석. 대전대학교 한의학연구소 문헌집. 2007;16(2):241-9.
  6. 정의민 등. 중의학 논문에 나타난 유방암의 연구 동향에 대한 고찰 - 중의학 논문을 중심으로 -. 대한한방부인과학회지. 2009;22(1):263-78.
  7. Tao J. et al. Cytotoxicity of Chinese motherwort (YiMuCao) aqueous ethanol extract is non-apoptotic and estrogen receptor independent on human breast cancer cells. J Ethnopharmacology. 2009;122(2):234-9.
  8. Liu J. et al. Coptis extracts enhance the anticancer effect of estrogen receptor antagonists on human breast cancer cells. Biochemistry Biophysical Research Communication. 2009;378(2):174-8. https://doi.org/10.1016/j.bbrc.2008.10.169
  9. Einbond LS. et al. Actein inhibits the Na+-K+-ATPase and enhances the growth inhibitory effect of digitoxin on human breast cancer cells. Biochemistry Biophysical Research Communication. 2008;375(4):608-13. https://doi.org/10.1016/j.bbrc.2008.08.054
  10. Nizamutdinova IT. et al. Tanshinone I effectively induces apoptosis in estrogen receptor-positive (MCF-7) and estrogen receptor-negative (MDA-MB-231) breast cancer cells. Internal J Oncology. 2008;33(3):485-91.
  11. Liu H. et al. Anti-tumor effect of honokiol alone and in combination with other anti-cancer agents in breast cancer. Europe J Pharmacology. 2008;591(1-3):43-51. https://doi.org/10.1016/j.ejphar.2008.06.026
  12. Yang L. et al. 23,24-Dihydrocucurbitacin B induces G2/M cell-cycle arrest and mitochondria-dependent apoptosis in human breast cancer cells (Bcap37.) Cancer Lett. 2007;256(2):267-78. https://doi.org/10.1016/j.canlet.2007.06.018
  13. Yap SP. et al. Molecular and pharmacodynamic properties of estrogenic extracts from the traditional Chinese medicinal herb, Epimedium. J Ethnopharmacology. 2007;113(2):218-24. https://doi.org/10.1016/j.jep.2007.05.029
  14. Einbond LS, The growth inhibitory effect of actein on human breast cancer cells is associated with activation of stress response pathways. Internal J Cancer. 2007;121(9):2073-83. https://doi.org/10.1002/ijc.22897
  15. Nangia-Makker P. et al. Inhibition of breast tumor growth and angiogenesis by a medicinal herb: Ocimum gratissimum. Internal J Cancer. 2007;121(4):884-94. https://doi.org/10.1002/ijc.22733
  16. Kummalue T. et al. Antiproliferative effect of Erycibe elliptilimba on human breast cancer cell lines. J Ethnopharmacol. 2007;110(3):439-43. https://doi.org/10.1016/j.jep.2006.10.025
  17. R. Brown. et al. Selective downregulation of EGF receptor and downstream MAPK pathway in human cancer cell lines by active components partially purified from the seeds of Livistona chinensis. Cancer Lett. 2007;248(1):137-46. https://doi.org/10.1016/j.canlet.2006.06.010
  18. Jiang J, Slivova V, Sliva D. Ganoderma lucidum inhibits proliferation of human breast cancer cells by down-regulation of estrogen receptor and NF-kappaB signaling. Internal J Oncology. 2006 ;29(3):695-703.
  19. Aung HH. et al. Cisplatin's tumoricidal effect on human breast carcinoma MCF-7 cells was not attenuated by American ginseng. Cancer Chemotherapy Pharmacology. 2007;59(3):369-374. https://doi.org/10.1007/s00280-006-0278-6
  20. Wu C. et al. Antiproliferative activities of parthenolide and golden feverfew extract against three human cancer cell lines. J Medicinal Food. 2006;9(1):55-61. https://doi.org/10.1089/jmf.2006.9.55
  21. Chiu LC. et al. Ethyl acetate extract of Patrinia scabiosaefolia downregulates anti-apoptotic Bcl-2/Bcl-X(L) expression, and induces apoptosis in human breast carcinoma MCF-7 cells independent of caspase-9 activation. J Ethnopharmacol. 2006;105(1-2):263-268. https://doi.org/10.1016/j.jep.2005.11.007
  22. Hsieh TC. et al. Differential control of growth, cell cycle progression, and expression of NF-kappaB in human breast cancer cells MCF-7, MCF-10A, and MDA-MB-231 by ponicidin and oridonin, diterpenoids from the chinese herb Rabdosia rubescens. Biochemistry Biophysical Research Communication. 2005;337(1):224-31. https://doi.org/10.1016/j.bbrc.2005.09.040
  23. Kang JX. et al. The extract of huanglian, a medicinal herb, induces cell growth arrest and apoptosis by upregulation of interferon-beta and TNF-alpha in human breast cancer cells. Carcinogenesis. 2005;26(11):1934-9. https://doi.org/10.1093/carcin/bgi154
  24. Zhang YX. et al. 11,11'-dideoxy-verticillin: a natural compound possessing growth factor receptor tyrosine kinase-inhibitory effect with anti-tumor activity. Anticancer Drugs. 2005;16(5):515-24. https://doi.org/10.1097/00001813-200506000-00007
  25. Rockwell S. et al. Alteration of the effects of cancer therapy agents on breast cancer cells by the herbal medicine black cohosh. Breast Cancer Rescue Treatment. 2005;90(3):233-9. https://doi.org/10.1007/s10549-004-4260-x
  26. Lee JC. et al. Plant-originated glycoprotein, G-120, inhibits the growth of MCF-7 cells and induces their apoptosis. Food Chemistry Toxicology. 2005;43(6):961-8. https://doi.org/10.1016/j.fct.2005.02.002
  27. Liao CH. et al. Antitumor mechanism of evodiamine, a constituent from Chinese herb Evodiae fructus, in human multiple-drug resistant breast cancer NCI/ADR-RES cells in vitro and in vivo. Carcinogenesis. 2005;26(5):968-75. https://doi.org/10.1093/carcin/bgi041
  28. Wang W, Li PP. The effects of herb lithospermum extract on MCF-7 cell and estrogen and progestogen levels in mice. Zhongguo Zhong Yao Za Zhi. 2003;28(11):1062-7.
  29. Jenner C, Filshie J. Galactorrhoea following acupuncture. Acupuncture Medicine. 2002;20(2-3):107-8. https://doi.org/10.1136/aim.20.2-3.107
  30. J. G. Greene. A factor analytic study of climacteric symptoms. Journal of Psychosomatic research. 1976;20:425-30. https://doi.org/10.1016/0022-3999(76)90005-2
  31. Porzio G. et al. Acupuncture in the treatment of menopause-related symptoms in women taking tamoxifen. Tumori. 2002;88(2):128-30.
  32. Filshie J. et al. Acupuncture and self acupuncture for long-term treatment of vasomotor symptoms in cancer patients-audit and treatment algorithm. Acupuncture Medicine. 2005;23(4):171-80. https://doi.org/10.1136/aim.23.4.171
  33. Vickers AJ. et al. Acupuncture for dyspnea in advanced cancer: a randomized, placebo-controlled pilot trial. BMC Palliat Care. 2005;18:4-5.
  34. Deng G. et al. Randomized, controlled trial of acupuncture for the treatment of hot flashes in breast cancer patients. J Clinical Oncology. 2007;25(35):5584-90. https://doi.org/10.1200/JCO.2007.12.0774
  35. Crew KD. et al. Pilot study of acupuncture for the treatment of joint symptoms related to adjuvant aromatase inhibitor therapy in postmenopausal breast cancer patients. J Cancer Survivor. 2007 ;1(4):283-91. https://doi.org/10.1007/s11764-007-0034-x
  36. Walker G. et al. Ear acupuncture for hot flushes--the perceptions of women with breast cancer. Complement Therapy Clinical Practice. 2007;13(4):250-7. https://doi.org/10.1016/j.ctcp.2007.06.003
  37. Alem M, Gurgel MS. Acupuncture in the rehabilitation of women after breast cancer surgery-a case series. Acupuncture Medicine. 2008;26(2):87-93.
  38. Hervik J, Mjaland O. Acupuncture for the treatment of hot flashes in breast cancer patients, a randomized, controlled trial. Breast Cancer Rescue Treatment. 2008;10:7.
  39. Shen J. et al. Electroacupuncture for control of myeloablative chemotherapy -induced emesis: A randomized controlled trial. JAMA. 2006;284(21):2755-61. https://doi.org/10.1001/jama.284.21.2755
  40. Gan TJ. et al. A randomized controlled comparison of electro-acupoint stimulation or ondansetron versus placebo for the prevention of postoperative nausea and vomiting. Anesthetic Analgesia. 2004 ;99(4):1070-5. https://doi.org/10.1213/01.ANE.0000130355.91214.9E
  41. Nedstrand E. et al. Psychological well-being improves in women with breast cancer after treatment with applied relaxation or electro-acupuncture for vasomotor symptom. J Psychosomatic Obstetrics and Gynecology. 2006;27(4):193-9. https://doi.org/10.1080/01674820600724797
  42. Frisk J. et al. Long-term follow-up of acupuncture and hormone therapy on hot flushes in women with breast cancer: a prospective, randomized, controlled multicenter trial. Climacteric. 2008 ;11(2):166-74. https://doi.org/10.1080/13697130801958709
  43. Dibble SL. et al. Acupressure for nausea: results of a pilot study. Oncology Nurse Forum. 2000;27(1):41-7.
  44. Roscoe JA. et al. Acustimulation wrist bands are not effective for the control of chemotherapy-induced nausea in women with breast cancer. J Pain Symptom Management. 2005;29(4):376-84. https://doi.org/10.1016/j.jpainsymman.2004.07.007
  45. Gardani G. et al. Effect of acupressure on nausea and vomiting induced by chemotherapy in cancer patients. Minerva Medicine. 2006;97(5):391-4.
  46. Lee MM. et al. Alternative therapies used by women with breast cancer in four ethnic populations. J Nationall Cancer Institution. 2000;92(1):42-7. https://doi.org/10.1093/jnci/92.1.42
  47. Boon H. et al. Use of complementary/alternative medicine by breast cancer survivors in Ontario: prevalence and perceptions. J Clinical Oncology. 2000;18(13):2501-4. https://doi.org/10.1200/JCO.2000.18.13.2501
  48. Harris PF. et al. Prevalence and treatment of menopausal symptoms among breast cancer survivors. J Pain Symptom Management. 2002;23(6):501-9. https://doi.org/10.1016/S0885-3924(02)00395-0
  49. Targ EF, Levine EG. The efficacy of a mind-body-spirit group for women with breast cancer: a randomized controlled trial. Gen Hospital Psychiatry. 2002;24(4):238-48. https://doi.org/10.1016/S0163-8343(02)00191-3
  50. Standish LJ. et al. Complementary and alternative medical treatment of breast cancer: a survey of licensed North American naturopathic physicians. Alternative Therapuetic Health Medicine. 2002;8(5):68-70.
  51. Ashikaga T. et al. Use of complimentary and alternative medicine by breast cancer patients: prevalence, patterns and communication with physicians. Support Care Cancer. 2002;10(7):542-8. https://doi.org/10.1007/s00520-002-0356-1
  52. Lengacher CA. et al. Frequency of use of complementary and alternative medicine in women with breast cancer. Oncology Nurse Forum. 2002;29(10):1445-52. https://doi.org/10.1188/02.ONF.1445-1452
  53. Gray RE. et al. Utilization of complementary /alternative services by women with breast cancer. J Health Social Policy. 2003;16(4):75-84. https://doi.org/10.1300/J045v16n04_04
  54. Lengacher CA. et al. Design and testing of the use of a complementary and alternative therapies survey in women with breast cancer. Oncology Nurse Forum. 2003;30(5):811-21. https://doi.org/10.1188/03.ONF.811-821
  55. Malik IA, Gopalan S. Use of CAM in delay in seeking medical advice for breast cancer. Europe J Epidemiology. 2003;18(8):817-22.
  56. Mills E. et al. Health food store recommendations: implications for breast cancer patients. Breast Cancer Research. 2003;5(6):300-2. https://doi.org/10.1186/bcr724
  57. Schonekaes K. et al. Use of complementary/alternative therapy methods by patients with breast cancer. Forsch Komplementary medicine Klass Naturheilkd. 2003;10(6):304-8. https://doi.org/10.1159/000075883
  58. Nahleh Z, Tabbara IA. Complementary and alternative medicine in breast cancer patients. Palliat Support Care. 2003;1(3):267-73.
  59. Henderson JW, Donatelle RJ. Complementary and alternative medicine use by women after completion of allopathic treatment for breast cancer. Alternative Therapuetic Health Medicine. 2004 ;10(1):52-7.
  60. Navo MA. et al. An assessment of the utilization of complementary and alternative medication in women with gynecologic or breast malignancies. J Clinical Oncology. 2004;22(4):671-7. https://doi.org/10.1200/JCO.2004.04.162
  61. Cui Y. et al. Use of complementary and alternative medicine by chinese women with breast cancer. Breast Cancer Rescue Treatment. 2004;86(1):89. https://doi.org/10.1023/B:BREA.0000032990.90079.74
  62. Nagel G, Hoyer H, Katenkamp D. Use of complementary and alternative medicine by patients with breast cancer: observations from a health-care survey. Support Care Cancer. 2004;12(11):789-96. https://doi.org/10.1007/s00520-004-0675-5
  63. Rakovitch E. et al. Complementary and alternative medicine use is associated with an increased perception of breast cancer risk and death. Breast Cancer Rescue Treatment. 2005;90(2):139-48. https://doi.org/10.1007/s10549-004-3779-1
  64. Roberts CS. et al. Patient-physician communication regarding use of complementary therapies during cancer treatment. J Psychosocial Oncology. 2005;23(4):35-60.
  65. Carlsson M. et al. Coping in women with breast cancer in complementary and conventional care over 5 years measured by the mental adjustment to cancer scale. J Alternative Complementary Medicine. 2005;11(3):441-7. https://doi.org/10.1089/acm.2005.11.441
  66. Lengacher CA. et al. Relief of symptoms, side effects, and psychological distress through use of complementary and alternative medicine in women with breast cancer. Oncol Nurse Forum. 2006;33(1):97-104. https://doi.org/10.1188/06.ONF.97-104
  67. Helyer LK. et al. The use of complementary and alternative medicines among patients with locally advanced breast cancer-a descriptive study. BMC Cancer. 2006;6:39. https://doi.org/10.1186/1471-2407-6-39
  68. Buettner C. et al. Correlates of use of different types of complementary and alternative medicine by breast cancer survivors in the nurses' health study. Breast Cancer Rescue Treatment. 2006 ;100(2):219-27. https://doi.org/10.1007/s10549-006-9239-3
  69. Susan G et al. Breast cancer patients' perspectives on and use of complementary and alternative medicine: Social Integrated Oncology. 2006;4(4):157-69. https://doi.org/10.2310/7200.2006.019
  70. Fasching PA. et al. Association of complementary methods with quality of life and life satisfaction in patients with gynecologic and breast malignancies. Support Care Cancer. 2007;15(11): 1277-84. https://doi.org/10.1007/s00520-007-0231-1
  71. Boon HS, Olatunde F, Zick SM. Trends in complementary/alternative medicine use by breast cancer survivors: comparing survey data from 1998 and 2005. BMC Womens Health. 2007;7:4. https://doi.org/10.1186/1472-6874-7-4
  72. Matthews AK. Complementary and alternative medicine use among breast cancer survivors. J Alternative Complementary Medicine. 2007;13(5):555-62. https://doi.org/10.1089/acm.2007.03-9040
  73. Mueller CM. et al. Complementary and alternative medicine use among women at increased genetic risk of breast and ovarian cancer. BMC Complementary Alternative Medicine. 2008;8:17. https://doi.org/10.1186/1472-6882-8-17
  74. Myers CD. et al. Familial and perceived risk of breast cancer in relation to use of complementary medicine. Myers Cancer Epidemiological Biomarkers Prevalence. 2008;17(6):1527-34. https://doi.org/10.1158/1055-9965.EPI-08-0028
  75. Carpenter CL, Ganz PA, Bernstein L. Complementary and alternative therapies among very long-term breast cancer survivors. Breast Cancer Rescue Treatment. 2008;10:20.
  76. Chen Z. et al. The use of complementary and alternative medicine among Chinese women with breast cancer. J Alternative Complementary Medicine. 2008;14(8):1049-55. https://doi.org/10.1089/acm.2008.0039
  77. Saxe GA. et al. Disclosure to physicians of CAM use by breast cancer patients: findings from the Women's Healthy Eating and Living Study. Integrated Cancer Therapy. 2008;7(3):122-9. https://doi.org/10.1177/1534735408323081
  78. Rao MR. et al. Anxiolytic effects of a yoga program in early breast cancer patients undergoing conventional treatment: a randomized controlled trial. Complementary Theruetic Medicine. 2009;17(1):1-8. https://doi.org/10.1016/j.ctim.2008.05.005
  79. Gumus AB, Cam O. Effects of emotional support-focused nursing interventions on the psychosocial adjustment of breast cancer patients. Asian Pacific J Cancer Prevention. 2008;9(4):691-7.
  80. Greenlee H. et al. Complementary and alternative therapy use before and after breast cancer diagnosis: the Pathways Study. Breast Cancer Rescue Treatment. 2009;1:31.
  81. Field KM. et al. Predictors of the use of complementary and alternative medicine (CAM) by women at high risk for breast cancer. Europe J Cancer. 2009;45(4):551-60. https://doi.org/10.1016/j.ejca.2008.09.023