Parasites, Hosts and Diseases

The Korea Society for Parasitology and Tropical Medicine (대한기생충학·열대의학회)
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High Prevalence of Haplorchis taichui, Phaneropsolus molenkampi, and Other Helminth Infections among People in Khammouane Province, Lao PDR

  • Chai, Jong-Yil (Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine, and Institute of Endemic Diseases, Seoul National University Medical Research Center) ;
  • Han, Eun-Taek (Department of Parasitology, College of Medicine, Kangwon National University) ;
  • Shin, Eun-Hee (Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine, and Institute of Endemic Diseases, Seoul National University Medical Research Center) ;
  • Sohn, Woon-Mok (Department of Parasitology and Institute of Health Sciences, Gyeongsang National University School of Medicine) ;
  • Yong, Tai-Soon (Department of Parasitology, College of Medicine, Yonsei University) ;
  • Eom, Keeseon S. (Department of Parasitology, College of Medicine, Chungbuk National University) ;
  • Min, Duk-Young (Department of Microbiology and Immunology, School of Medicine, Eulji University) ;
  • Um, Jin-Young (Korea Association of Health Promotion) ;
  • Park, Min-Sung (Korea Association of Health Promotion) ;
  • Hoang, Eui-Hyug (Korea Association of Health Promotion) ;
  • Phommasack, Bounlay (Department of Hygiene and Prevention, Ministry of Public Health) ;
  • Insisiengmay, Bounnaloth (Department of Hygiene and Prevention, Ministry of Public Health) ;
  • Lee, Soon-Hyung (Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine, and Institute of Endemic Diseases, Seoul National University Medical Research Center) ;
  • Rim, Han-Jong (Department of Parasitology, College of Medicine, Korea University)
  • Published : 2009.09.30
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Abstract

The prevalence of liver and intestinal helminth infections, including Opisthorchis, Haplorchis, Phaneropsolus, hookworms, Enterobius, and Taenia, was surveyed in Khammouane province, Lao PDR. Fecal specimens were collected from 1,242 people (590 men and 652 women) in 3 Mekong riverside villages and were examined by the Kate-Katz thick smear technique. The overall helminth egg positive rate was 81.1%. The positive rate for small trematode eggs, including Opisthorchis viverrini, heterophyids, and lecithodendriids, was 81.1% and the positive rate for hookworms was 6.7%. To obtain adult worms, 35 people who were positive for small trematode eggs were treated with 20-30 mg/kg praziquantel and 10-15 mg/kg pyrantel pamoate, and then purged. Diarrheic stools were collected from 33 of these people and searched for helminth parasites using a stereomicroscope. Mixed infections with various helminths (Haplorchis taichui, Haplorchis yokogawai, Prosthodendrium molenkampi, Phaneropsolus bonnei, echinostomes, hookworms, Trichostrongylus spp., Trichuris trichiura, Enterobius vermicularis, and/or Taenia saginata) were found. The total number of helminth specimens collected was 20,907 (approximately 634 per person). The most common species was H. taichui, followed by P. molenkampi, 0. viverrini, P. bonnei, E. vermicularis, hookworms, and Trichostrongylus spp. These results show that diverse species of intestinal nematodes, trematodes, and cestodes are infecting humans in Khammouane province, Lao PDR.

Keywords

References

  1. World health Organization. Controlling Disease Due to Helminth Infections (eds. Crompton DWT et al.). Geneva, Switzerland. World Health Organization. 2003, p 1-248
  2. Chai JY, Murrell KD, Lymbry A. Fishborne parasitic zoonoses: status and issues. Int J Parasitol 2005; 35: 1233-1254 https://doi.org/10.1016/j.ijpara.2005.07.013
  3. Chai JY, Lee SH. Food-borne intestinal trematode infections in the Republic of Korea. Parasitol Int 2002; 51: 129-154 https://doi.org/10.1016/S1383-5769(02)00008-9
  4. Shin EH, Guk SM, Lee SH, Chai JY. Trends in parasitic diseases in the Republic of Korea. Trends Parasitol 2008; 24: 143-150 https://doi.org/10.1016/j.pt.2007.12.003
  5. Jeon HK, Kim KH, Chai JY, Yang HJ, Rim HJ, Eom KS. Sympatric distribution of three human Taenia tapeworms collected between 1935 and 2005 in Korea. Korean J Parasitol 2008; 46: 235-241 https://doi.org/10.3347/kjp.2008.46.4.235
  6. Sornmani S, Pathammavong O, Bunnag T, Impand P, Intarakhao C, Thirachantra S. An epidemiological survey of human intestinal parasites in Vientiane, Laos. Southeast Asian J Trop Med Public Health 1974; 5: 541-546
  7. Kobayashi J, Vannachone B, Xeutvongsa A, Manivong K, Ogawa S, Sato Y, Pholsena K. Prevalence of intestinal parasitic infection among children in two villages in Lao PDR. Southeast Asian J Trop Med Public Health 1996; 27: 562-565
  8. Chai JY, Hongvanthong B. A small-scale survey of intestinal helminthic infections among the residents near Pakse, Laos. Korean J Parasitol 1998; 36: 55-58 https://doi.org/10.3347/kjp.1998.36.1.55
  9. Rim HJ, Chai JY, Min DY, Cho SY, Eom KS, Hong SJ, Sohn WM, Yong TS, Deodato G, Standgaard H, Phommasack B, Yun CY, Hoang EH. Prevalence of intestinal parasite infections on a national scale among primary schoolchildren in Laos. Parasitol Res 2003; 91: 267-272 https://doi.org/10.1007/s00436-003-0963-x
  10. Giboda M, Ditrich O, Scholz T, Viengsay T, Bouaphanh S. Human Opisthorchis and Haplorchis infections in Laos. Trans R Soc Trop Med Hyg 1991; 85: 538-540 https://doi.org/10.1016/0035-9203(91)90248-W
  11. Chai JY, Park JH, Han ET, Guk SM, Shin EH, Lin A, Kim JL, Sohn WM, Yong TS, Eom KS, Min DY, Hwang EH, Phommasack B, Insisiengmai B, Rim HJ. Mixed infections with Opisthorchis viverrini and intestinal flukes in residents of Vientiane Municipality and Saravane Province in Laos. J Helminthol 2005; 79: 283-289 https://doi.org/10.1079/JOH2005302
  12. Chai JY, Han ET, Guk SM, Shin EH, Sohn WM, Yong TS, Eom KS, Lee KH, Jeong HG, Ryang YS, Hoang EH, Phommasack B, Insisiengmai B, Lee SH, Rim HJ. High prevalence of liver and intestinal fluke infections among residents of Savannakhet Province in Laos. Korean J Parasitol 2007; 45: 213-218 https://doi.org/10.3347/kjp.2007.45.3.213
  13. Sayasone S, Vonghajack Y, Vanmany M, Rasphone O, Tesana S, Utzinger J, Akkhavong K, Odermatt P. Diversity of human intestinal helminthiasis in Lao PDR. Trans R Soc Trop Med Hyg 2009; 103: 247-254 https://doi.org/10.1016/j.trstmh.2008.10.011
  14. Manning GS, Lertprasert P, Watanasirmkit K, Chetty C. A description of newly discovered intestinal parasites endemic to northeastern Thailand. J Med Ass Thailand 1971; 54: 466-474
  15. Radomyos P, Radomyos B, Tungtrongchitr A. Multi-infection with helminths in adults from northeast Thailand as determined by post-treatment fecal examination of adult worms. Trop Med Parasitol 1994; 45: 133-135
  16. Yong TS, Lee JH, Sim SB, Lee JW, Min DY, Chai JY, Eom KS, Sohn WM, Lee SH, Rim HJ. Differential diagnosis of Trichostrongylus and hookworms eggs via PCR using ITS-1 sequence. Korean J Parasitol 2007; 45: 69-74 https://doi.org/10.3347/kjp.2007.45.1.69
  17. John DT, Petri WA Jr. Markell and Voge's Medical Parasitology. 9th ed. St. Louis, Missouri, USA. Saunders Elsevier. 2006, p 266

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