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Paralytic Shellfish Poisoning of Mediterranean mussels from Jinhae Bay in Korea

진해만 해역에서 지중해담치 (Mytilus galloprovincialis)의 마비성패독 독화 양상

  • Published : 2009.08.31

Abstract

This study looked at toxicity of Mediterranean mussels, Mytilus galloprovincialis, which had accumulated paralytic shellfish toxins (PST) from early March to late May 2005 at Jinhae Bay, Korea. Alexandrium sp. was observed in low densities (< 1,000 cells/L) at the beginning of the study in March, increased rapidly in April, declined rapidly and disappeared in May. Although low densities of Alexandrium sp. were observed in March, mussel toxicity exceeded regulation level ($80{\mu}g$ STXeq. /100 g). Peak PSP (Paralytic Shellfish Poisoning) toxicity in the mussels occurred during high Alexandrium sp. cell densities in April. Mussels toxicity decreased with decline of Alexandrium sp. cell density. Major toxin components identified were $GTX_1$, $GTX_4$, followed by $C_1$, $C_2$, $GTX_2$, $GTX_3$ and neoSTX. Trace or sporadic toxin components were STX, $GTX_5$, $dcGTX_2$, $dcGTX_3$ and dcSTX. Toxin component analysis from the middle to end of the study showed that $11{\beta}$-epimers ($GTX_{3,4}$, $C_2$) were converted into $11{\alpha}$-epimers ($GTX_{1,2}$, $C_1$) and started to determine STX.

Keywords

References

  1. Asakawa, M., K. Miyazawa, H. Takayama and T. Noguchi. 1995. Dinoflagellate Alexandrium tamarense as the source of paralytic shellfish poison (PSP) contained in bivalves from Hiro- shima Bay, Hiroshima Prefecture, Japan. Toxicon, 33, 691-697 https://doi.org/10.1016/0041-0101(94)00177-A
  2. Beitler, M.K. and J. Liston. 1990. Uptake and tissue distribution of PSP toxins in butter clams. In: Toxic Marine Phytoplankton. Graneli, E., B. Sundstrom, L. Elder, and D.M. Anderson, eds. Elsevier Science Publishers, New York, U.S.A., 257-262
  3. Bricelj, V.M., J.H. Lee and A.D. Cembella. 1991. Influence of dinoflagellate cell toxicity on uptake and loss of paralytic shellfish toxins in the northern quahog, Mercenaria mercenaria. Mar. Ecol. Prog. Ser., 74, 33-46 https://doi.org/10.3354/meps074033
  4. Bricelj, V.M. and S.E. Shumway. 1998. Paralytic shellfish toxins in bivalve molluscs: occurrence, transfer kinetics, and biotransformation. Rev. Fish. Sci., 6, 315-383 https://doi.org/10.1080/10641269891314294
  5. Chang, D.S., I.S. Shin, J.H. Pyeun and Y.H. Park. 1987. A study on paralytic shellfish poison of sea mussel, Mytilus edulis - Specimen caused food poisoning accident in Gamchun Bay, Pusan, Korea, 1986. Bull. Kor. Fish. Soc., 20, 293-300
  6. Fukuyo, Y., H. Takano, M. Chikara and K. Matsuoka. 1990. Red tide organisms in Japan - An illustrated taxonomic guide. Uchida Rokakuho, Tokyo, Japan, 1-430
  7. Hallegraeff, G.M. 2003. Harmful algal blooms: a global overview. In: Manual on Harmful Marine Microalgae. Hallegraeff, G.M., D.M. Anderson and A.D, Cembella, eds. UNESCO, Paris, France, 19-49
  8. Han, M.S., J.K. Jeon and Y.O. Kim. 1992. Occurrence of dinoflagellate Alexandrium tamarense, a causative organism of paralytic shellfish poisoning in Chinhae Bay, Korea. J. Plankton Res., 11, 1581-1592 https://doi.org/10.1093/plankt/14.11
  9. Han, M.S., lK. Jeon and Y.H. Yoon. 1993, Distribution and toxin profiles of Alexandrium tamarense (Lebour) Balech (Dinoflagellate) in the Southeastern Coastal Waters, Korea. Kor. J. Phycol., 8, 7-13
  10. Jeon, J.K., M.S. Han and H.O. Kim. 1996. Paralytic shellfish toxins in the mussels and Alexandrium tamarense (dinoflagellate) from Gamraepo, Korea in 1989. In: Harmful and Toxic Algal Blooms, Yasumoto, T., Y. Oshima and Y. Fukuyo, eds. UNESCO, Paris, France, 65-68
  11. Jeon, J.K. and M.S. Han. 1998. Monitoring of intoxication and toxin composition on wild mussels (Mytilus corsucus) from coastal waters near Koje island, Korea in 1996 and 1997. J. Kor. Fish. Soc., 31, 817-822
  12. Jeon, lK., M.S. Han, Y.J. Park and M.Y. Yoon. 1998. Paralytic shellfish toxin composition and intoxication of scallops (Patinopecten yessoensis) in Kangnung coastal waters of East Sea in 1997. J. Kor. Fish. Soc., 31, 813-816
  13. Jeon, J.K. and H.T. Huh. 1989. Paralytic shellfish poison in the cultured mussel, Mytilus edulis galloprovincialis. J. Oceanol. Soc. Kor., 24, 79-83
  14. Kim, C.-H. 1995. Paralytic shellfish toxin profiles of the dinoflagellate Alexandrium species isolated from benthic cysts in Jinhae Bay, Korea. J. Kor. Fish. Soc., 28, 364-372
  15. Kim, C.-H. and J.B. Shin. 1997. Harmful and toxic red tide algal development and toxins production in Korean coastal waters. Algae, 12, 269-276 https://doi.org/10.1111/j.1444-2906.2008.01541.x
  16. Kim, C.J., C.-H. Kim and Y. Sako. 2005a. Paralytic shellfish poisoning toxin analysis of the genus Alexandrium (Dinophyceae) occurring in Korean coastal waters. Fish. Sci., 71, 1-11 https://doi.org/10.1111/j.1444-2906.2005.00924.x
  17. Kim, Y.S., J.S. Lee, J.H. Jang, K.Y. Kim and C.H. Kim. 2005b. Occurrence of toxic Alexandrium and intoxification of two mollusk species by paralytic shellfish poisoning toxins on the southeastern coast of Korea. J. Fish. Sci. Technol., 8, 76-82 https://doi.org/10.5657/fas.2005.8.2.076
  18. Lee, J.S., J,K. Jeon, M.S. Han, Y. Oshima and T. Yasumoto. 1992. Paralytic shellfish toxins in the mussel, Mytilus edulis and dinoflagellate Alexandrium tamarense from Jinhae Bay, Korea. Bull. Kor. Fish. Soc., 25, 144-155
  19. Lee, J.S., I.S. Shin, Y.M. Kim and D.S. Chang. 1997. Paralytic shellfish toxins in the mussel, Mytilus edulis, caused the shellfish poisoning accident at Geoje, Korea, in 1996. J. Kor. Fish. Soc., 30, 158- 160
  20. Min, D.K. 2004. Mollusks in Korea. Hanguel graphics, Busan, Korea, 1-566
  21. Murakami, R., K. Yamamoto and T. Noguchi. 1999. Difference in PSP composition among various parts of surf clam. J. Food Hyg. Soc. Japan, 40, 55-61 https://doi.org/10.3358/shokueishi.40.55
  22. NFRDI. 1998-2003. Report of research on the examination of bivalves sanitation in Korean coast. National Fisheries Research and Development Institute
  23. Oikawa H., T. Fujita, K. Satio, S. Watabe, M. Satomi and Y. Yano. 2004. Comparison of paralytic shellfish poisoning toxin between carnivorous crabs (Telmessus acutidens and Charybdis japonica) and their prey mussel (Mytilus galloprovincialis) in an inshore food chain. Toxicon, 43, 713 -719 https://doi.org/10.1016/j.toxicon.2004.03.003
  24. Oshima, Y., K. Sugino, H. Itakura, M. Hirota and T. Yasumoto. 1990. Comparative studies on paralytic shellfish toxin profile of dinoflagellates and bivalves. In: Toxic Marine Phytoplankton. Graneli, E., B. Sundstrom, L. Edler and D.M. Anderson, eds. Elsevier, New York, U.S.A., 391-396
  25. Oshima, Y. 1995a. Psot-column derivatization HPLC methods for paralytic shellfish poisons. In: Manual on Harmful Marine Microalgae. Hallegraeff, G.M., D.M. Anderson and A.D. Cembella, eds. UNESCO, Paris, France, 81-94
  26. Oshima, Y. 1995b. Chemical and enzymatic transformation of paralytic shellfish toxins in marine organisms. In: Harmful Marine Algal Blooms. Lassua, P., G. Arzul, E. Erard, P. Gentien and C. Marcaillou, eds., Lavoisier, Paris, France, 475- 480
  27. Park, T.-G., C.-H. Kim and Y. Oshima. 2004. Paralytic shellfish toxin profile of different geographic population of Gymnodinium catenatum (Dinophyceae) in Korean coastal waters. Phycological Res., 52, 300- 305 https://doi.org/10.1111/j.1440-1835.2004.tb00339.x
  28. Shim J.H. 1994. Marine phytoplankton. In: Illustrated encyclopedia of fauna & flora of Korea. Ministry of Education, Chungnam, Korea, 34, 1-487
  29. Shin, I.S.. and Y.M. Kim. 2000. Studies for reestablishment of approval toxin amount in paralytic shellfish poison-infested shellfish 5. Comparison of toxicity and toxin composition of paralytic shellfish poison between blue mussel, Mytilus edulis and oyster, Crassostrea gigas. J. Fd. Hyg. Safety, 15, 287-292
  30. Sekiguchi, K., S. Sato, S. Kaga, T. Ogata and M. Kodama. 2001. Accumulation of paralytic shellfish poisoning toxins in bivalves and an ascidian fed on Alexandrium tamarense cells. Fish. Sci., 67, 301-305 https://doi.org/10.1046/j.1444-2906.2001.00228.x
  31. Taylor, F.J.R., Y. Fukuyo, J. Larsen and G.J. Hallegraeff. 2003. Taxonomy of harmful dinoflagellates. In: Manual on Harmful Marine Microalgae. Hallegraeff, G.M., D.M. Anderson and A.D. Cembella, eds., UNESCO, Paris, France, 389-432

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