Journal of Preventive Medicine and Public Health

The Korean Society for Preventive Medicine (대한예방의학회)
권호 표지
DOI QR코드

DOI QR Code

Body Weight at Birth and at Age Three and Respiratory Illness in Preschool Children

  • Jeong, Yool-Won (Department of Preventive Medicine, School of Medicine, Ewha Womans University) ;
  • Jung-Choi, Kyung-Hee (Department of Preventive Medicine, School of Medicine, Ewha Womans University) ;
  • Lee, Jin-Hwa (Department of Internal Medicine, School of Medicine, Ewha Womans University) ;
  • Lee, Hwa-Young (Department of Anatomy, School of Medicine, Ewha Womans University) ;
  • Park, Eun-Ae (Department of Pediatrics, School of Medicine, Ewha Womans University) ;
  • Kim, Young-Ju (Department of Obstetrics & Gynecology, School of Medicine, Ewha Womans University) ;
  • Ha, Eun-Hee (Department of Preventive Medicine, School of Medicine, Ewha Womans University) ;
  • Oh, Se-Young (Department of Food & Nutrition, College of Human Ecology, Kyung Hee University) ;
  • Park, Hye-Sook (Department of Preventive Medicine, School of Medicine, Ewha Womans University)
  • Received : 2010.04.05
  • Accepted : 2010.06.22
  • Published : 2010.09.30
Download PDF
⟨ Previous Next ⟩

Abstract

Objectives: The purpose of this study was to examine the associations of current body weight and body mass index (BMI) at age three and birth weight in developing chronic respiratory illness in childhood and identify possible interaction underlying its mechanism. Methods: The study was carried out with 422 children who were enrolled in a hospital-based birth cohort. Birth related anthropometric data were collected at birth. At age 3 years, the presence of respiratory symptoms was evaluated by using the Korean version of core questionnaire for wheezing and asthma from the International Study of Asthma and Allergies in Childhood (ISAAC). Physical examination was carried out to measure the child's weight and height. Results: Children in the lowest birth weight tertile (aOR = 3.97, 95% CI = 0.94-16.68) or highest BMI tertile (aOR = 3.68, 95% CI = 1.24-10.95) at three years of age were at an increased risk of chronic respiratory illness. Children who were initially in the lowest birth weight tertile but now belong in the highest weight tertile had higher risk of chronic respiratory illness compared to those who had remained in the middle tertile (OR=16.35, 95% CI=1.66-160.57). Conclusions: Children with lower birth weight or higher BMI were at an increased risk of chronic respiratory illness. In addition, children who were initially in the lowest birth weight tertile but are now in the highest weight tertile had higher risk of chronic respiratory illness compared to those who remained in the middle tertile.

Keywords

References

  1. Flaherman V, Rutherford GW. A meta-analysis of the effect of high weight on asthma. Arch Dis Child 2006; 91(4): 334-339. https://doi.org/10.1136/adc.2005.080390
  2. Taveras EM, Camargo CA Jr, Rifas-Shiman SL, Oken E, Gold DR, Weiss ST, et al. Association of birth weight with asthma-related outcomes at age 2 years. Pediatr Pulmonol 2006; 41(7): 643-648. https://doi.org/10.1002/ppul.20427
  3. Caudri D, Wijga A, Gehring U, Smit HA, Brunekreef B, Kerkhof M, et al. Respiratory symptoms in the first 7 years of life and birth weight at term: the PIAMA Birth Cohort. Am J Respir Crit Care Med 2007; 175(10): 1078-1085. https://doi.org/10.1164/rccm.200610-1441OC
  4. Sin DD, Spier S, Svenson LW, Schopflocher DP, Senthilselvan A, Cowie RL, et al. The relationship between birth weight and childhood asthma. Arch Pediatr Adolesc Med 2004; 158(1): 60-64. https://doi.org/10.1001/archpedi.158.1.60
  5. Hong SJ, Ahn KM, Lee SY, Kim KE. The prevalences of asthma and allergic diseases in Korean children. Korean J Pediatr 2008; 51(4): 343-350. (Korean) https://doi.org/10.3345/kjp.2008.51.4.343
  6. Camargo CA Jr, Weiss ST, Zhang S, Willett WC, Speizer FE. Prospective study of body mass index, weight change, and risk of adult-onset asthma in women. Arch Intern Med 1999; 159(21): 2582-2588. https://doi.org/10.1001/archinte.159.21.2582
  7. Chen Y, Dales R, Krewski D, Breithaupt K. Increased effects of smoking and obesity on asthma among female Canadians: the National Population Health Survey, 1994- 1995. Am J Epidemiol 1999; 150(3): 255-262. https://doi.org/10.1093/oxfordjournals.aje.a009996
  8. Beckett WS, Jacobs DR Jr, Yu X, Iribarren C, Williams OD. Asthma is associated with weight gain in females but not males, independent of physical activity. Am J Respir Crit Care Med 2001; 164(11): 2045-2050. https://doi.org/10.1164/ajrccm.164.11.2004235
  9. Schachter LM, Peat JK, Salome CM. Asthma and atopy in overweight children. Thorax 2003; 58(12): 1031-1035. https://doi.org/10.1136/thorax.58.12.1031
  10. Musaad SMA, Patterson T, Ericksen M, Lindsey M, Dietrich K, Succop P, et al. Comparison of anthropometric measures of obesity in childhood allergic asthma: central obesity is most relevant. J Allergy Clin Immunol 2009; 123(6): 1321-1327. https://doi.org/10.1016/j.jaci.2009.03.023
  11. Gilliland FD, Berhane K, Islam T, McConeell R, Gauderman WJ, Gilliland SS, et al. Obesity and the risk of newly diagnosed asthma in school-age children. Am J Epidemiol 2003; 158(5): 406-415. https://doi.org/10.1093/aje/kwg175
  12. Ong KK, Dunger DB. Birth weight, infant growth and insulin resistance. Eur J Endocrinol 2004; 151(Suppl 3): 131-139. https://doi.org/10.1530/eje.0.151U131
  13. Lee H, Yoon SJ, Ahn H, Ha M, Ko KS, June KJ. A Survey on prenatal environmental risk factors for mothers of low birth weight infants in Asan-city. Korean J Prev Med 2004; 37(1): 11-16.
  14. Leadbitter P, Pearce N, Cheng S, Sears MR, Holdaway MD, Flannery EM, et al. Relationship between fetal growth and the development of asthma and atopy in childhood. Thorax 1999; 54(10): 905-910. https://doi.org/10.1136/thx.54.10.905
  15. Dik N, Tate RB, Manfreda J, Anthonisen NR. Risk of physician-diagnosed asthma in the first 6 years of life. Chest 2004; 126(4): 1147-1153. https://doi.org/10.1378/chest.126.4.1147
  16. Yuan W, Basso O, Sorensen HT, Olsen J. Fetal growth and hospitalization with asthma during early childhood: a follow-up study in Denmark. Int J Epidemiol 2002; 31(6): 1240-1245. https://doi.org/10.1093/ije/31.6.1240
  17. Eriksson JG, Forsén T, Tuomilehto J, Winter PD, Osmond C, Barker DJ. Catch-up growth in childhood and death from coronary heart disease: longitudinal study. BMJ 1999; 318(7181): 427-431. https://doi.org/10.1136/bmj.318.7181.427
  18. Tzoulaki I, Jarvelin MR, Hartikainen AL, Leinonen M, Pouta A, Paldanius M, et al. Size at birth, weight gain over the life course, and low-grade inflammation in young adulthood: northern Finland 1966 Birth Cohort Study. Eur Heart J 2008; 29(8): 1049-1056. https://doi.org/10.1093/eurheartj/ehn105
  19. Forsén T, Eriksson J, Tuomilehto J, Reunanen A, Osmond C, Barker D. The fetal and childhood growth of persons who develop type 2 diabetes. Ann Intern Med 2000; 133(3): 176-182.
  20. Turner S, Zhang G, Young S, Cox M, Goldblatt J, Landau L, et al. Associations between postnatal weight gain, change in postnatal pulmonary function, formula feeding and early asthma. Thorax 2008; 63(3): 234-239. https://doi.org/10.1136/thx.2006.064642
  21. Lucas JS, Inskip HM, Godfrey KM, Foreman CT, Warner JO, Gregson RK, et al. Small size at birth and greater postnatal weight gain: Relationships to diminished infant lung function. Am J Respir Crit Care Med 2004; 170(5): 534-540. https://doi.org/10.1164/rccm.200311-1583OC
  22. Mai XM, Gaddlin PO, Nilsson L, Leijon I. Early rapid weight gain and current overweight in relation to asthma in adolescents born with very low birth weight. Pediatr Allergy Immunol 2005; 16(5): 380-385. https://doi.org/10.1111/j.1399-3038.2005.00290.x
  23. Hancox RJ, Poulton R, Greene JM, McLachlan CR, Pearce MS, Sears MR. Associations between birth weight, early childhood weight gain and adult lung function. Thorax 2009; 64(3): 228-232. https://doi.org/10.1136/thx.2008.103978
  24. Hong SJ, Kim SW, Oh JW, Rah YH, Ahn YM, Kim KE, et al.The validity of the ISAAC written questionnaire and the ISAAC video questionnaire for predicting asthma associated with bronchial hyperreactivity in a group of 13-14 year old Korean schoolchildren. J Korean Med Sci 2003; 18(1): 48-52. https://doi.org/10.3346/jkms.2003.18.1.48
  25. von Mutius E, Schwartz J, Neas LM, Dockery D, Weiss ST. Relation of body mass index to asthma and atopy in children: the National Health and Nutrition Examination Study III. Thorax 2001; 56(11): 835-838. https://doi.org/10.1136/thorax.56.11.835
  26. Castro-Rodriguez JA, Holberg CJ, Morgan WJ, Wright AL, Martinez FD. Increased incidence of asthmalike symptoms in girls who become overweight or obese during the school years. Am J Respir Crit Care Med 2001; 163(6): 1344-1349. https://doi.org/10.1164/ajrccm.163.6.2006140
  27. Chinn S. Obesity and asthma: evidence for and against a causal relation. J Asthma 2003; 40(1): 1-16. https://doi.org/10.1081/JAS-120017202
  28. Stenius-Aarniala B, Poussa T, Kvarnström J, Grönlund EL, Ylikahri M, Mustajoki P. Immediate and long term effects of weight reduction in obese people with asthma: randomised controlled study. BMJ 2000; 320(7238): 827-832. https://doi.org/10.1136/bmj.320.7238.827
  29. Weiner P, Waizman J, Weiner M, Rabner M, Magadle R, Zamir D. Influence of excessive weight loss after gastroplasty for morbid obesity on respiratory muscle performance. Thorax 1998; 53(1): 39-42. https://doi.org/10.1136/thx.53.1.39
  30. Litonjua AA, Sparrow D, Celedon JC, DeMolles D, Weiss ST. Association of body mass index with the development of methacholine airway hyperresponsiveness in men: the Normative Aging Study. Thorax 2002; 57(7): 581-585. https://doi.org/10.1136/thorax.57.7.581
  31. Barker DJ, Godfrey KM, Fall C, Osmond C, Winter PD, Shaheen SO. Relation of birth weight and childhood respiratory infection to adult lung function and death from chronic obstructive airways disease. BMJ 1991; 303(6804): 671-675. https://doi.org/10.1136/bmj.303.6804.671
  32. Frankel S, Elwood P, Sweetnam P, Yarnell J, Smith GD. Birthweight, body-mass index in middle age, and incident coronary heart disease. Lancet 1996; 348(9040): 1478-1480. https://doi.org/10.1016/S0140-6736(96)03482-4
  33. Lin Y, Lechner AJ. Surfactant content and type II cell development in fetal guinea pig lungs during prenatal starvation. Pediatr Res 1991; 29(3): 288-291. https://doi.org/10.1203/00006450-199103000-00013
  34. Eriksson M, Tynelius P, Rasmussen F. Associations of birthweight and infant growth with body composition at age 15--the COMPASS study. Paediatr Perinat Epidemiol 2008; 22(4): 379-388. https://doi.org/10.1111/j.1365-3016.2008.00944.x
  35. Singhal A, Cole TJ, Fewtrell M, Deanfield J, Lucas A. Is slower early growth beneficial for long-term cardiovascular health? Circulation 2004; 109(9): 1108-1113. https://doi.org/10.1161/01.CIR.0000118500.23649.DF
  36. Huxley RR, Shiell AW, Law CM. The role of size at birth and postnatal catch-up growth in determining systolic blood pressure: a systematic review of the literature. J Hypertens 2000; 18(7): 815-831. https://doi.org/10.1097/00004872-200018070-00002
  37. Bhargava SK, Sachdev HS, Fall CH, Osmond C, Lakshmy R, Barker DJ, et al. Relation of serial changes in childhood body-mass index to impaired glucose tolerance in young adulthood. N Engl J Med 2004; 350(9): 865-875. https://doi.org/10.1056/NEJMoa035698
  38. Stettler N, Zemel BS, Kumanyika S, Stallings VA. Infant weight gain and childhood overweight status in a multicenter, cohort study. Pediatrics 2002; 109(2): 194-199. https://doi.org/10.1542/peds.109.2.194
  39. Ekelund U, Ong K, Linné Y, Neovius M, Brage S, Dunger B, et al. Upward weight percentile crossing in infancy and early childhood independently predicts fat mass in young adults: the Stockholm Weight Development Study (SWEDES). Am J Clin Nutr 2006; 83(2): 324-330. https://doi.org/10.1093/ajcn/83.2.324
  40. Rusconi F, Galassi C, Corbo GM, Forastiere F, Biggeri A, Ciccone G, et al. Risk factors for early, persistent, and lateonset wheezing in young children. SIDRIA Collaborative Group. Am J Respir Crit Care Med 1999; 160(5 Pt 1): 1617-1622. https://doi.org/10.1164/ajrccm.160.5.9811002

Cited by

  1. Growth of preschool children at high risk for asthma 2 years after discontinuation of fluticasone vol.128, pp.5, 2011, https://doi.org/10.1016/j.jaci.2011.06.027
  2. Body mass index may modify asthma prevalence among low-birth-weight children. vol.176, pp.1, 2010, https://doi.org/10.1093/aje/kwr484
  3. Fetal growth and risk of childhood asthma and allergic disease vol.42, pp.10, 2010, https://doi.org/10.1111/j.1365-2222.2012.03997.x
  4. Prenatal and Postnatal Maternal Stress and Wheeze in Urban Children : Effect of Maternal Sensitization vol.186, pp.2, 2010, https://doi.org/10.1164/rccm.201201-0162oc
  5. Overview of Noncommunicable Diseases in Korean Children and Adolescents: Focus on Obesity and Its Effect on Metabolic Syndrome vol.46, pp.4, 2013, https://doi.org/10.3961/jpmph.2013.46.4.173
  6. Excess weight in preschool children with a history of severe bronchiolitis is associated with asthma vol.50, pp.5, 2010, https://doi.org/10.1002/ppul.23053
  7. Birth weight and childhood wheezing disorders: a systematic review and meta-analysis vol.69, pp.5, 2015, https://doi.org/10.1136/jech-2014-204783
  8. Association between obesity and asthma - epidemiology, pathophysiology and clinical profile vol.29, pp.2, 2010, https://doi.org/10.1017/s0954422416000111
  9. The Dynamic Relationship Between Asthma and Obesity in Schoolchildren vol.189, pp.6, 2010, https://doi.org/10.1093/aje/kwz257