Journal of Mycology and Infection

The Korean Society for Medical Mycology (대한의진균학회)
권호 표지

Antifungal Effects of the Extracts and Essential Oils from Foeniculum vulgare and Illicium verum against Candida albicans

소회향, 대회향 추출물과 정유의 Candida albicans 에 대한항진균 효과

  • Park, Sung-Ho (Department of Microbiology, College of Medicine, Korea University) ;
  • Seong, In-Wha (Department of Microbiology, College of Medicine, Korea University)
  • 박성호 (고려대학교 의과대학 미생물학교실) ;
  • 성인화 (고려대학교 의과대학 미생물학교실)
  • Published : 2010.12.30
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Abstract

Background: Candida albicans is a member of the normal flora of the skin, mucous membrane and gastrointestinal tract. Vaginal candidiasis remains a significant problem in women in childbearing age, Majority of the cases are caused by C. albicans and recurrence is common in spite of topical treatment. Objective: The purpose of this study is to develop the antifungal agent from the medicinal herbs traditionally used in Korea. Method: In this study, the extracts and essential oils from Foeniculum vulgare and Illicium verum were examined for antifungal activities against C. albicans. Result: Dichloromethane extracts and essential oils from Foeniculum vulgare and Illicium verum showed antifungal activity against C. albicans. One fraction from Illicium verum with antifungal activity was founf out as 1-methoxy-4-(2-prophenyl) benzene. Conclusion: Dichloromethane extract and 1-methoxy-4-(2-prophenyl) benzene with antifungal activity from Illicium verum could be the candidate for a new antifungal agent for candidiasis and other fungal diseases.

Keywords

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