KSBB Journal

The Korean Society for Biotechnology and Bioengineering (한국생물공학회)
권호 표지

Concentration of Heavy Metals in Granule, Globular and Liquid types of Herbal Medicines

과립제와 환제 및 현탁액으로 만들어진 생약제제의 중금속 농도

  • Bae, Jong-Sup (Department of Herbal Pharmaceutical Engineering, Daegu Haany University) ;
  • Park, Jong-Pil (Department of Herbal Pharmaceutical Engineering, Daegu Haany University) ;
  • Kim, Yong-Ung (Department of Herbal Pharmaceutical Engineering, Daegu Haany University) ;
  • Park, Moon-Ki (Department of Herbal Pharmaceutical Engineering, Daegu Haany University)
  • 배종섭 (대구한의대학교 한방제약공학과) ;
  • 박종필 (대구한의대학교 한방제약공학과) ;
  • 김용웅 (대구한의대학교 한방제약공학과) ;
  • 박문기 (대구한의대학교 한방제약공학과)
  • Received : 2009.12.11
  • Accepted : 2010.01.03
  • Published : 2010.02.28
Download PDF
⟨ Previous Next ⟩

Abstract

This study is an endeavor to evaluate the safety of medicines from heavy metals, prescribed on the basis of herbal medicinal system and oriental medical prescription which are circulated much recently. For that, six globular types, six granular types and seven liquid types of herbal medicines were bought to compare and analyze the content of heavy metals, such as As, Pb, Cd and Hg, which are harmful to human body. The concentration of As was 0.219 mg/kg to 1.243 mg/kg, Cd was 0.0282 mg/kg to 0.8481 mg/kg, Pb was 0.9582 mg/kg to 5.233 mg/kg and Hg was 0.001 mg/kg to 0.01 mg/kg in globular and granular types. Otherwise, in the liquid types, As was 0.0123 mg/kg to 0.5024 mg/kg, Cd was 0.0128 mg/kg to 0.0568 mg/kg, Pb was 0.1755 mg/kg to 0.712 mg/kg, and Hg was 0.001 mg/kg to 0.002 mg/kg. It was found that the concentration of heavy metals in liquid types herbal medicines was relatively lower than globular and granular types. It is required to treat, manufacture and manage herbal medicines for safety.

Keywords

References

  1. Jung, D. H. and M. K. Park (2008) The content of heavy metals in manufactured herbal medicines. J. of the Environmental Sciences 17: 12-133.
  2. Kim, S. Y. (2005) A Study on the Risk Assessment of Hazardous Materials in Herbal Medicines. M. S. Thesis. Daegu Haany University, Daegu, Korea.
  3. Park, H. M., K. H. Choi, J. Y. lung, and S. D. Lee (2006) Metal exposure through consumption of herbal medicine, and estimation of health risk among Korean population. Kor. J. Env. Helth. 32: 186-191.
  4. Park, M. K., S. Y. Kim, and H. U. Hwang (2004) A study on the heavy metal contents in herbal medicines. -Cultivated herbal medicines at north Gyeongbuk area-. J. of the Environmental Sciences 13: 1117-1122. https://doi.org/10.5322/JES.2004.13.12.1117
  5. Park, G. H. (1992) Pb, Cu, Zn contaminants and their correlation of soil, leave and bark of ginkgo. B and ambient air adjacent to a heavy traffic road side. Kor. J. Env. Helth. 18: 19-25.
  6. Hong, S. U. and S. H. Park (1984) Studies on the pollution of heavy metal in soil and vegetable. Kor. J. Env. Helth. 10: 33-45.
  7. Rhee, S. J., S. O. Kiln, and W. K. Choe, (1992) Effect of cadmium dose injection on peroxidative damage in rat liver in Korean. J. Korean Soc. Food Sci. Nutr. 21: 601-607.
  8. Jung, S. Y., S. J. Rhee, and J. A. Yang (1990) Effect of dietary vitamin E levels on lipid peroxidation and enzyme activities of antioxidative system in brain of cadmium administered rats in Korean. J. Korean Soc. Food Sci. Nutr. 25: 575-580.
  9. Rabinowits, M. B. and G. W. Weatherill (1973) Lead metabolism in the normal human; stable isotope studies. Science. 182: 275.
  10. Choi, S. I., J. H. Lee, and S. R. Lee (1994) Effect of green teabeverage for the removal of cadmiym and lead by animal experiments in Korean. Korean J. Food Sci. Technol. 26: 745-749.
  11. Schroeder, H. A. and W. H. Vinton (1962) Hypertension induced in rats by small doses of cadmium. Am. J. Physiol. 202: 515-518.
  12. Nordberg, M. (1984) General aspects of cadmium: transport, uptake and metabolism by the kidney. Inviron. Health Persp. 54: 13-20. https://doi.org/10.1289/ehp.845413
  13. Choi, S. I., J. B. Hwang, J. H. Kwon, and H. K. Kim (1998) Suppressing Effect of Medicinal Plants on the Intestinal Absorption of Heavy Metals Korean. J. Food Sci. Technol. 30: 456-460.
  14. Kim, J. H. (2004) Residues of the organochlorine pesticides and heavy metal in culture environment of ginseng on sangju. The Korean Society of Environmental Toxicology 19: 183-189.
  15. Korea Food & Drug Administration. http://www.kfda. go.kr.(2005).
  16. Park, M. K., H. J. Lee, K. J. Kim, and Y. S. Moon (2005) The correlation of heavy metal contents in herbal medicines and their soils at north Gyeongbuk area. J. Environ. Sci. 14: 185-192. https://doi.org/10.5322/JES.2005.14.2.185
  17. Kang, S. J. and H. S. Choi (1972) Effect of road side soil and vegetation with lead and zinc by motor vehicles. Korea J. Bot. 15: 55-61.