The Journal of Korean Medicine (대한한의학회지)

The Society of Korean Medicine (대한한의학회)
권호 표지

Retrospective Observation of Liver Function Parameters for 101 Patients Using Herbal Drugs for One Month

1개월 이상 한약을 복용한 101명의 간기능 검사에 대한 후향적 관찰

  • Kim, Dong-Min (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung Hee University) ;
  • Kim, Hyee-Kwon (Gapyeong Public Health Center) ;
  • Cho, Seong-Yeun (Dept. of Acupuncture & Moxibustion, Kangnam KyungHee Korean Hospital, Kyung Hee University) ;
  • Kim, Yong-Suk (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung Hee University) ;
  • Nam, Sang-Soo (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung Hee University)
  • 김동민 (경희대학교 한의과대학 침구학교실) ;
  • 김회권 (가평군 보건소) ;
  • 조성연 (경희대학교 강남경희한방병원 침구과) ;
  • 김용석 (경희대학교 한의과대학 침구학교실) ;
  • 남상수 (경희대학교 한의과대학 침구학교실)
  • Received : 2010.01.18
  • Accepted : 2010.03.03
  • Published : 2010.03.30
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Abstract

Objective: The purpose of this study was to investigate the level of safety on liver functions when Korean herbal medicine was taken internally. Method: 101 inpatients who took Korean herbal medicine were enrolled and liver function test (aspartic aminotransferase, alanine aminotransferase, alkaline phosphatase, total bilirubin, gamma glutamyltranspeptidase, albumin, lactate dehydrogenase) was performed on admission and 1 month later. Results: In 101 patients, alkaline phosphatase and gamma glutamyltranspeptidase decreased significantly compared with the value taken on admission (p<0.05) but aspartic aminotransferase, alanine aminotransferase, total bilirubin, albumin, and lactate dehydrogenase were not significantly changed (p>0.05). In the patients who took Scutellaria baicalensis (n=34), alkaline phosphatase decreased and albumin increased significantly (p<0.05). Among the patients who took Atractylodes macrocephala (n=29), alkaline phosphatase decreased significantly (p<0.05). In the patients who took Glycyrrhiza uralensis or Paeonia lactiflora, liver function parameters were not significantly changed (p>0.05). On admission 11 patients had abnormal liver function and 2 patients had liver injury while 7 patients had abnormal liver function and 2 patients showed liver injury 1 month later. Conclusions: This study suggests that prescribed Korean herbal medicine does not injure liver function.

Keywords

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