Journal of the Korean Applied Science and Technology (한국응용과학기술학회지)

The Korean Society of Applied Science and Technology (한국응용과학기술학회)
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Microbiological Effects of Xanthorrhizol against Candida albicans

잔토리졸의 칸디다균 항균 효과

  • Cho, Wan-Goo (College of Alternative Medicine, Jeonju University) ;
  • Kim, Hyo-Jin (College of Alternative Medicine, Jeonju University)
  • 조완구 (전주대학교 대체의학대학 기초의과학과) ;
  • 김효진 (전주대학교 대체의학대학 천연화장품학)
  • Received : 2010.02.02
  • Accepted : 2010.03.11
  • Published : 2010.03.30
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Abstract

The objective of this study was to evaluate the antifungal properties of xanthorrhizol (extract from curcuma xanthorrhiza) against Candida albicans. Some of the commercial products were evaluated for their ability to inhibit growth of C. albicans. OTC product containing povidone iodide and cosmetic grade product with surfactants were tested. Antifungal activity was shown in 1.56% of OTC product, however, there was no antifungal effect in cosmetic product. For the comparison, we tested several materials. Povidone iodide, lemon tea tree oil and xanthorrhizol showed antifungal activities against C albicans in 0.25, 0.062 and 0.007%, respectively. We also tested the antifungal effects of povidone iodide and xanthorrhizol in surfactant base. Test results revealed that 2.5% of povidone iodide and 0.156% of xanthorrhizol showed similar antifungal effects. These findings support the application of xanthorrhizol for vaginal cleanser or personal cares using antifungal effect.

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References

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