Journal of Periodontal and Implant Science

Korean Academy of Periodontology (대한치주과학회)
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Evaluating intra- and inter-examiner reproducibility in histometric measurement: one-wall intrabony periodontal defects in beagle dogs

  • Kim, Soo-Kyung (Department of Periodontology, Oral Science Research Center, Yonsei University College of Dentistry) ;
  • Choi, Eun-Hee (Department of Biostatistics, Yonsei University College of Medicine) ;
  • Lee, Jung-Seok (Department of Periodontology, Oral Science Research Center, Yonsei University College of Dentistry) ;
  • Kim, Tae-Gyun (Department of Periodontology, Oral Science Research Center, Yonsei University College of Dentistry) ;
  • Choi, Seong-Ho (Department of Periodontology, Oral Science Research Center, Yonsei University College of Dentistry) ;
  • Cho, Kyoo-Sung (Department of Periodontology, Oral Science Research Center, Yonsei University College of Dentistry) ;
  • Chai, Jung-Kiu (Department of Periodontology, Oral Science Research Center, Yonsei University College of Dentistry) ;
  • Kim, Chong-Kwan (Department of Periodontology, Oral Science Research Center, Yonsei University College of Dentistry)
  • Received : 2010.05.01
  • Accepted : 2010.07.07
  • Published : 2010.08.31
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Abstract

Purpose: Accurate and exact measurement is an important factor for generating meaningful results in any properly designed study. If all the participating examiners are able to yield similar results, it will be possible to evaluate the objective results of the study more easily and quickly. The purpose of this study was to evaluate the intra- and inter-examiner reproducibility of histometric measurements in the intrabony periodontal defect model. Methods: One wall intrabony defects were surgically created at the distal aspect of the second and the medial aspect of the fourth mandibular premolars in the right and left jaw quadrants in twenty beagle dogs and the defect sites received the following ${\beta}$-tri calcium phosphate, growth differentiation factor-0, growth differentiation factor-100 and sham surgery. Histometric analysis was performed after 8 weeks. Histometric parameters were recorded and repeated at three months interval by three examiners. Intra- and inter-examiner reproducibility was assessed. Results: Most parameters of all the groups showed high intra- and inter-examiner reproducibility. Parameters including defect height, bone regeneration height, cementum regeneration height, and formation of junctional epithelium yielded interexaminer correlation ${\geq}0.9$. The intra-examiner reproducibility showed a high result, over 0.9. Conclusions: Histometric evaluation of the one-wall intra-alveolar periodontal defect model showed high reproducibility not only for a single given examiner but also among the three examiners.

Keywords

References

  1. Koo KT, Polimeni G, Albandar JM, Wikesjo UM. Periodontal repair in dogs: examiner reproducibility in the supraalveolar periodontal defect model. J Clin Periodontol 2004;31:439-42. https://doi.org/10.1111/j.1600-051X.2004.00508.x
  2. Hatakeyama Y, Uzel MI, Santana RB, Ruben MP. Relationship between position of probe tip and periodontal tissues after periodontal surgery in dogs. Int J Periodontics Restorative Dent 2005;25:247-55.
  3. Armitage GC, Svanberg GK, Loe H. Microscopic evaluation of clinical measurements of connective tissue attachment levels. J Clin Periodontol 1977;4:173-90. https://doi.org/10.1111/j.1600-051X.1977.tb02271.x
  4. van der Velden U, de Vries JH. Introduction of a new periodontal probe: the pressure probe. J Clin Periodontol 1978;5:188-97. https://doi.org/10.1111/j.1600-051X.1978.tb02279.x
  5. Koo KT, Polimeni G, Qahash M, Kim CK, Wikesjo UM. Periodontal repair in dogs: guided tissue regeneration enhances bone formation in sites implanted with a coral-derived calcium carbonate biomaterial. J Clin Periodontol 2005;32:104-10. https://doi.org/10.1111/j.1600-051X.2004.00632.x
  6. Barnhart HX, Lokhnygina Y, Kosinski AS, Haber M. Comparison of concordance correlation coefficient and coefficient of individual agreement in assessing agreement. J Biopharm Stat 2007;17:721-38. https://doi.org/10.1080/10543400701329497
  7. Quinn C, Haber MJ, Pan Y. Use of the concordance correlation coefficient when examining agreement in dyadic research. Nurs Res 2009;58:368-73. https://doi.org/10.1097/NNR.0b013e3181b4b93d
  8. Lee J, Tran Q, Seeba G, Wikesjo UM, Susin C. The critical-size supraalveolar peri-implant defect model: reproducibility in histometric data acquisition of alveolar bone formation and osseointegration. J Clin Periodontol 2009;36:1067-74. https://doi.org/10.1111/j.1600-051X.2009.01487.x
  9. Liao JJ, Lewis JW. A note on concordance correlation coefficient. PDA J Pharm Sci Technol 2000;54:23-6.
  10. Barnhart HX, Haber M, Song J. Overall concordance correlation coefficient for evaluating agreement among multiple observers. Biometrics 2002;58:1020-7. https://doi.org/10.1111/j.0006-341X.2002.01020.x
  11. Sculean A, Nikolidakis D, Schwarz F. Regeneration of periodontal tissues: combinations of barrier membranes and grafting materials - biological foundation and preclinical evidence: a systematic review. J Clin Periodontol 2008;35:106-16. https://doi.org/10.1111/j.1600-051X.2008.01263.x
  12. Kim CS, Choi SH, Chai JK, Cho KS, Moon IS, Wikesjo UM, et al. Periodontal repair in surgically created intrabony defects in dogs: influence of the number of bone walls on healing response. J Periodontol 2004;75:229-35. https://doi.org/10.1902/jop.2004.75.2.229
  13. Kim HY, Kim CS, Jhon GJ, Moon IS, Choi SH, Cho KS, et al. The effect of safflower seed extract on periodontal healing of 1-wall intrabony defects in beagle dogs. J Periodontol 2002;73:1457-66. https://doi.org/10.1902/jop.2002.73.12.1457
  14. Wikesjo UM, Hagen K, Nielsen DD. Periodontal repair in dogs: effect of saliva contamination of the root surface. J Periodontol 1990;61:559-63. https://doi.org/10.1902/jop.1990.61.9.559
  15. Wikesjo UM, Lim WH, Razi SS, Sigurdsson TJ, Lee MB, Tatakis DN, et al. Periodontal repair in dogs: a bioabsorbable calcium carbonate coral implant enhances space provision for alveolar bone regeneration in conjunction with guided tissue regeneration. J Periodontol 2003;74:957-64. https://doi.org/10.1902/jop.2003.74.7.957
  16. Wikesjo UM, Nilveus R. Periodontal repair in dogs: effect of wound stabilization on healing. J Periodontol 1990;61:719-24. https://doi.org/10.1902/jop.1990.61.12.719
  17. Shrout PE, Fleiss JL. Intraclass correlations: uses in assessing rater reliability. Psychol Bull 1979;86:420-8. https://doi.org/10.1037/0033-2909.86.2.420
  18. Jomha NM, Anoop PC, Elliott JA, Bagnall K, McGann LE. Validation and reproducibility of computerised cell-viability analysis of tissue slices. BMC Musculoskelet Disord 2003;4:5. https://doi.org/10.1186/1471-2474-4-5
  19. Barnhart HX, Song J, Haber MJ. Assessing intra, inter and total agreement with replicated readings. Stat Med 2005;24:1371-84. https://doi.org/10.1002/sim.2006
  20. Barnhart HX, Haber MJ, Lin LI. An overview on assessing agreement with continuous measurements. J Biopharm Stat 2007;17:529-69. https://doi.org/10.1080/10543400701376480
  21. Lin LI. A concordance correlation coefficient to evaluate reproducibility. Biometrics 1989;45:255-68. https://doi.org/10.2307/2532051
  22. Wang SF, Leknes KN, Zimmerman GJ, Sigurdsson TJ, Wikesjo UM, Selvig KA. Intra - and inter-examiner reproducibility in constant force probing. J Clin Periodontol 1995;22:918-22. https://doi.org/10.1111/j.1600-051X.1995.tb01795.x
  23. Shaoi J, Zhong B. Assessing the agreement between two quantitative assays with repeated measurements. J Biopharm Stat 2004;14:201-12. https://doi.org/10.1081/BIP-120028515
  24. Shultz SJ, Nguyen AD, Windley TC, Kulas AS, Botic TL, Beynnon BD. Intratester and intertester reliability of clinical measures of lower extremity anatomic characteristics: implications for multicenter studies. Clin J Sport Med 2006;16:155-61. https://doi.org/10.1097/00042752-200603000-00012
  25. Kingman A, Albandar JM. Methodological aspects of epidemiological studies of periodontal diseases. Periodontol 2000 2002;29:11-30. https://doi.org/10.1034/j.1600-0757.2002.290102.x

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