Korean journal of dermatology (대한피부과학회지)

Korean Dermatological Association (대한피부과학회)
권호 표지

Clinical Observation of Cutaneous Sarcoidosis

피부 유육종증의 임상적 고찰

  • Suh, Sung-Won (Department of Dermatology, School of Medicine, Pusan National University) ;
  • Kim, Su-Han (Department of Dermatology, School of Medicine, Pusan National University) ;
  • Jung, Do-Sang (Department of Dermatology, School of Medicine, Pusan National University) ;
  • Ko, Hyun-Chang (Department of Dermatology, School of Medicine, Pusan National University) ;
  • Kwon, Kyung-Sool (Department of Dermatology, School of Medicine, Pusan National University) ;
  • Kim, Moon-Bum (Department of Dermatology, School of Medicine, Pusan National University)
  • 서성원 (부산대학교 의과대학 피부과학교실) ;
  • 김수한 (부산대학교 의과대학 피부과학교실) ;
  • 정도상 (부산대학교 의과대학 피부과학교실) ;
  • 고현창 (부산대학교 의과대학 피부과학교실) ;
  • 권경술 (부산대학교 의과대학 피부과학교실) ;
  • 김문범 (부산대학교 의과대학 피부과학교실)
  • Received : 2010.01.30
  • Accepted : 2010.03.31
  • Published : 2010.04.30
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Abstract

Background: Sarcoidosis is a chronic idiopathic disorder characterized by the formation of noncaseating granulomas. Multiple organs may be involved, including the skin, lung, lymphatic systems, liver, spleen and eyes. On average, 25% of sarcoidosis cases have cutaneous involvement. Objective: The purpose of this study was to investigate the clinical characteristics of cutaneous sarcoidosis and the involvement of systemic organs according to clinical types of skin lesions. Methods: A total of 32 patients diagnosed by histologic examination at Hospital from 2001 to 2009 with cutaneous sarcoidosis were enrolled in this study. The clinical features were obtained by reviewing medical records, clinical photographs and radiological images. Results: The male to female ratio was 1 : 3 and 78.2% of patients were in their fifth to seventh decades. The most common cutaenous lesions were nodules (56.3%), especially the subcutaneous type (21.9%). The most frequently involved organ type was intrathoracic (71.9%), followed by the peripheral lymph nodes (25%), spleen (6.3%), and eyes (6.3%). Most patients with subcutaneous nodules, erythema nodosa, lupus pernio and discoid lupus-like plaques showed systemic involvement, whereas most patients with nodules or papules did not show systemic involvement. Of particular note, patients with subcutaneous nodules and lupus pernio showed more frequent involvement of the peripheral lymph nodes, spleen and intrathoracic region. Conclusion: In this study, patients with subcutaneous nodules and plaques showed more frequent systemic involvement, while most patients with nodules or papules showed no systemic involvement.

Keywords

Acknowledgement

Supported by : 부산대학교

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