Journal of The Korean Ophthalmological Society (대한안과학회지)

The Korean Ophthalmological Society (대한안과학회)
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Mean Macular Volume in Normal Korean Eyes Measured by Spectral-domain Optical Coherence Tomography

스펙트럼영역 빛간섭단층촬영기로 측정한 한국인 정상안의 황반부 용적

  • Kang, Myeong-Su (Department of Ophthalmology, Dankook University Medical College) ;
  • Kyung, Sung-Eun (Department of Ophthalmology, Dankook University Medical College) ;
  • Chang, Moo-Hwan (Department of Ophthalmology, Dankook University Medical College)
  • 강명수 (단국대학교 의과대학 안과학교실) ;
  • 경성은 (단국대학교 의과대학 안과학교실) ;
  • 장무환 (단국대학교 의과대학 안과학교실)
  • Received : 2009.12.23
  • Accepted : 2010.05.14
  • Published : 2010.08.15
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Abstract

Purpose: To evaluate the mean macular volume in normal Korean eyes using spectral-domain optical coherence tomography. Methods: The present study consisted of 132 patients (212 eyes) with no ophthalmic evidence of retinopathy and who had a best corrected visual acuity of 1.0 or better. The total macular volume was measured using spectral-domain optical coherence tomography and was analyzed according to age group, sex, degree of refractive error and presence of systemic disease such as diabetes and hypertension. Results: The mean total macular volume of all subjects was 10.07 ${\pm}$ 0.45 $mm^3$, with means of 10.13 ${\pm}$ 0.40 $mm^3$, 10.05 ${\pm}$ 0.43 $mm^3$ and 9.97 ${\pm}$ 0.58 $mm^3$ measured for the respective A, B, and C age groups. There was a significant difference between male and female patients. In addition, there was a significant difference between diabetic patients in group C and normal subjects. However, there was no significant difference according to degree of refractive error. Conclusions: The measured value of mean macular volume in normal Korean eyes can be expected to provide a standard value for diagnosing retinal disease and the need for careful follow-up.

목적: 스펙트럼영역 빛간섭단층촬영기(SD-OCT)를 이용하여 한국인 정상안의 총 황반부 용적을 알아보고자 하였다. 대상과 방법: 안저검사상 정상이며, 교정시력 1.0 이상인 20세 이후의 한국인 132명 212안을 대상으로 SD-OCT를 이용하여 연령대별, 성별, 굴정이상의 정도 그리고 고혈압 혹은 당뇨 등의 전신질환 유무에 따라 총 황반부 용적을 비교 분석하였다. 결과: 전체 대상안의 평균 총 황반부 용적은 10.07 ${\pm}$ 0.45 $mm^3$였다. 청년군은 10.13 ${\pm}$ 0.40 $mm^3$, 장년군은 10.05 ${\pm}$ 0.43 $mm^3$, 노년군은 9.97 ${\pm}$ 0.58 $mm^3$로 측정되었고, 남성은 10.12 ${\pm}$ 0.46 $mm^3$, 여성은 9.97 ${\pm}$ 0.40 $mm^3$로 나타나 의미 있는 차이(p=0.028)를 보였다. 노년군에서 당뇨병 환자와 정상인은 의미 있는 차이(p=0.020)를 보였으며, 굴절이상에 따른 평균 황반부 용적의 차이는 의미가 없는 것으로 나타났다. 결론: 한국인 정상안의 평균 황반부 용적은 향후 황반부 병변의 진단과 경과관찰에 유용한 기준을 제공할 수 있을 것으로 기대된다.

Keywords

Acknowledgement

Supported by : 단국대학교

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