References
- Warner-Schmidt JL, Duman RS. Hippocampal neurogenesis: opposing effects of stress and antidepressant treatment. Hippocampus 2006;16: 239-249. https://doi.org/10.1002/hipo.20156
- Mellstrom B, Torres B, Link WA, Naranjo JR. The BDNF gene: exemplifying complexity in Ca2+ -dependent gene expression. Crit Rev Neurobiol 2004;16:43-49. https://doi.org/10.1615/CritRevNeurobiol.v16.i12.40
- Lu B, Pang PT, Woo NH. The yin and yang of neurotrophin action. Nat Rev Neurosci 2005;6:603-614. https://doi.org/10.1038/nrn1726
- Miller FD, Kaplan DR. Neurotrophin signaling pathways regulating neu-ronal apoptosis. Cell Mol Life Sci 2001;58:1045-1053. https://doi.org/10.1007/PL00000919
- Duman RS. Pathophysiology of depression: the concept of synaptic pla-sticity. Eur Psychiatry 2002;17 Suppl 3:306-310. https://doi.org/10.1016/S0924-9338(02)00654-5
- Castren E, Voikar V, Rantamaki T. Role of neurotrophic factors in depression. Curr Opin Pharmacol 2007;7:18-21. https://doi.org/10.1016/j.coph.2006.08.009
- Smith MA, Makino S, Kvetnansky R, Post RM. Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neu-rotrophin-3 mRNAs in the hippocampus. J Neurosci 1995;15:1768-1777.
- Ueyama T, Kawai Y, Nemoto K, Sekimoto M, Tone S, Senba E. Immobilization stress reduced the expression of neurotrophins and their receptors in the rat brain. Neurosci Res 1997;28:103-110. https://doi.org/10.1016/S0168-0102(97)00030-8
- Rasmusson AM, Shi L, Duman R. Downregulation of BDNF mRNA in the hippocampal dentate gyrus after re-exposure to cues previously associated with footshock. Neuropsychopharmacology 2002;27:133-142. https://doi.org/10.1016/S0893-133X(02)00286-5
- Pizarro JM, Lumley LA, Medina W, Robison CL, Chang WE, Alagappan A, et al. Acute social defeat reduces neurotrophin expression in brain cortical and subcortical areas in mice. Brain Res 2004;1025:10-20. https://doi.org/10.1016/j.brainres.2004.06.085
- Roceri M, Hendriks W, Racagni G, Ellenbroek BA, Riva MA. Early maternal deprivation reduces the expression of BDNF and NMDA receptor subunits in rat hippocampus. Mol Psychiatry 2002;7:609-616. https://doi.org/10.1038/sj.mp.4001036
- Russo-Neustadt A, Ha T, Ramirez R, Kesslak JP. Physical activity-antidepressant treatment combination: impact on brain-derived neurotrophic factor and behavior in an animal model. Behav Brain Res 2001;120: 87-95. https://doi.org/10.1016/S0166-4328(00)00364-8
- Schaaf MJ, de Jong J, de Kloet ER, Vreugdenhil E. Downregulation of BDNF mRNA and protein in the rat hippocampus by corticosterone. Brain Res 1998;813:112-120. https://doi.org/10.1016/S0006-8993(98)01010-5
- Dwivedi Y, Rizavi HS, Pandey GN. Antidepressants reverse corticosterone-mediated decrease in BDNF expression: dissociation in regulation of specific exons by antidepressants and corticosterone. Neuroscience 2006;139:1017-1029. https://doi.org/10.1016/j.neuroscience.2005.12.058
- Chao HM, Sakai RR, Ma LY, McEwen BS. Adrenal steroid regulation of neurotrophic factor expression in the rat hippocampus. Endocrinology 1998;139:3112-3118. https://doi.org/10.1210/en.139.7.3112
- Tsankova NM, Berton O, Renthal W, Kumar A, Neve RL, Nestler EJ. Sustained hippocampal chromatin regulation in a mouse model of depres-sion and antidepressant action. Nat Neurosci 2006;9:519-525. https://doi.org/10.1038/nn1659
- Duman RS, Monteggia LM. A neurotrophic model for stress-related mood disorders. Biol Psychiatry 2006;59:1116-1127. https://doi.org/10.1016/j.biopsych.2006.02.013
- Muller MB, Toschi N, Kresse AE, Post A, Keck ME. Long-term repetitive transcranial magnetic stimulation increases the expression of brain-derived neurotrophic factor and cholecystokinin mRNA, but not neuropeptide tyrosine mRNA in specific areas of rat brain. Neuropsychopharmacology 2000;23:205-215. https://doi.org/10.1016/S0893-133X(00)00099-3
- Altar CA, Laeng P, Jurata LW, Brockman JA, Lemire A, Bullard J, et al. Electroconvulsive seizures regulate gene expression of distinct neurotrophic signaling pathways. J Neurosci 2004;24:2667-2677. https://doi.org/10.1523/JNEUROSCI.5377-03.2004
- Balu DT, Hoshaw BA, Malberg JE, Rosenzweig-Lipson S, Schechter LE, Lucki I. Differential regulation of central BDNF protein levels by antidepressant and non-antidepressant drug treatments. Brain Res 2008; 1211:37-43. https://doi.org/10.1016/j.brainres.2008.03.023
- Coppell AL, Pei Q, Zetterstrom TS. Bi-phasic change in BDNF gene expression following antidepressant drug treatment. Neuropharmacology 2003;44:903-910. https://doi.org/10.1016/S0028-3908(03)00077-7
- De Foubert G, Carney SL, Robinson CS, Destexhe EJ, Tomlinson R, Hi-cks CA, et al. Fluoxetine-induced change in rat brain expression of brain-derived neurotrophic factor varies depending on length of treatment. Neuroscience 2004;128:597-604. https://doi.org/10.1016/j.neuroscience.2004.06.054
- Altieri M, Marini F, Arban R, Vitulli G, Jansson BO. Expression analysis of brain-derived neurotrophic factor (BDNF) mRNA isoforms after chronic and acute antidepressant treatment. Brain Res 2004;1000:148-155. https://doi.org/10.1016/j.brainres.2003.12.028
- Hajszan T, MacLusky NJ, Leranth C. Short-term treatment with the antidepressant fluoxetine triggers pyramidal dendritic spine synapse formation in rat hippocampus. Eur J Neurosci 2005;21:1299-1303. https://doi.org/10.1111/j.1460-9568.2005.03968.x
- Sairanen M, O'Leary OF, Knuuttila JE, Castren E. Chronic antidepressant treatment selectively increases expression of plasticity-related proteins in the hippocampus and medial prefrontal cortex of the rat. Neuroscience 2007;144:368-374. https://doi.org/10.1016/j.neuroscience.2006.08.069
- Saarelainen T, Hendolin P, Lucas G, Koponen E, Sairanen M, MacDonald E, et al. Activation of the TrkB neurotrophin receptor is induced by antidepressant drugs and is required for antidepressant-induced behavioral effects. J Neurosci 2003;23:349-357.
- Monteggia LM, Barrot M, Powell CM, Berton O, Galanis V, Gemelli T, et al. Essential role of brain-derived neurotrophic factor in adult hippocampal function. Proc Natl Acad Sci U S A 2004;101:10827-10832. https://doi.org/10.1073/pnas.0402141101
- Altar CA, Whitehead RE, Chen R, Wortwein G, Madsen TM. Effects of electroconvulsive seizures and antidepressant drugs on brain-derived neurotrophic factor protein in rat brain. Biol Psychiatry 2003;54:703-709. https://doi.org/10.1016/S0006-3223(03)00073-8
- MacQueen GM, Ramakrishnan K, Croll SD, Siuciak JA, Yu G, Young LT, et al. Performance of heterozygous brain-derived neurotrophic factor knockout mice on behavioral analogues of anxiety, nociception, and depression. Behav Neurosci 2001;115:1145-1153. https://doi.org/10.1037/0735-7044.115.5.1145
- Zorner B, Wolfer DP, Brandis D, Kretz O, Zacher C, Madani R, et al. Forebrain-specific trkB-receptor knockout mice: behaviorally more hyperactive than "depressive". Biol Psychiatry 2003;54:972-982. https://doi.org/10.1016/S0006-3223(03)00418-9
- Chen B, Dowlatshahi D, MacQueen GM, Wang JF, Young LT. Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication. Biol Psychiatry 2001;50:260-265. https://doi.org/10.1016/S0006-3223(01)01083-6
- Dowlatshahi D, MacQueen GM, Wang JF, Young LT. Increased temporal cortex CREB concentrations and antidepressant treatment in major depression. Lancet 1998;352:1754-1755. https://doi.org/10.1016/S0140-6736(05)79827-5
- Fujimura H, Altar CA, Chen R, Nakamura T, Nakahashi T, Kambayashi J, et al. Brain-derived neurotrophic factor is stored in human platelets and released by agonist stimulation. Thromb Haemost 2002;87:728-734.
- Pan W, Banks WA, Fasold MB, Bluth J, Kastin AJ. Transport of brain-derived neurotrophic factor across the blood-brain barrier. Neuropharmacology 1998;37:1553-1561. https://doi.org/10.1016/S0028-3908(98)00141-5
- Poduslo JF, Curran GL. Permeability at the blood-brain and blood-nerve barriers of the neurotrophic factors: NGF, CNTF, NT-3, BDNF. Brain Res Mol Brain Res 1996;36:280-286. https://doi.org/10.1016/0169-328X(95)00250-V
- Gonul AS, Akdeniz F, Taneli F, Donat O, Eker C, Vahip S. Effect of treatment on serum brain-derived neurotrophic factor levels in depressed patients. Eur Arch Psychiatry Clin Neurosci 2005;255:381-386. https://doi.org/10.1007/s00406-005-0578-6
- Karege F, Perret G, Bondolfi G, Schwald M, Bertschy G, Aubry JM. Decreased serum brain-derived neurotrophic factor levels in major depress-ed patients. Psychiatry Res 2002;109:143-148. https://doi.org/10.1016/S0165-1781(02)00005-7
- Karege F, Bondolfi G, Gervasoni N, Schwald M, Aubry JM, Bertschy G. Low brain-derived neurotrophic factor (BDNF) levels in serum of depressed patients probably results from lowered platelet BDNF release unrelated to platelet reactivity. Biol Psychiatry 2005;57:1068-1072. https://doi.org/10.1016/j.biopsych.2005.01.008
- Shimizu E, Hashimoto K, Okamura N, Koike K, Komatsu N, Kumakiri C, et al. Alterations of serum levels of brain-derived neurotrophic factor (BDNF) in depressed patients with or without antidepressants. Biol Psychiatry 2003;54:70-75. https://doi.org/10.1016/S0006-3223(03)00181-1
- Lee BH, Kim H, Park SH, Kim YK. Decreased plasma BDNF level in depressive patients. J Affect Disord 2007;101:239-244. https://doi.org/10.1016/j.jad.2006.11.005
- Brunoni AR, Lopes M, Fregni F. A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression. Int J Neuropsychopharmacol 2008;11:1169-1180. https://doi.org/10.1017/S1461145708009309
- Yoshimura R, Mitoma M, Sugita A, Hori H, Okamoto T, Umene W, et al. Effects of paroxetine or milnacipran on serum brain-derived neurotrophic factor in depressed patients. Prog Neuropsychopharmacol Biol Psychiatry 2007;31:1034-1037. https://doi.org/10.1016/j.pnpbp.2007.03.001
- Matrisciano F, Bonaccorso S, Ricciardi A, Scaccianoce S, Panaccione I, Wang L, et al. Changes in BDNF serum levels in patients with depression disorder (MDD) after 6 months treatment with sertraline, escitalopram, or venlafaxine. J Psychiatr Res 2009;43:247-254. https://doi.org/10.1016/j.jpsychires.2008.03.014
- Lee HY, Kim YK. Plasma brain-derived neurotrophic factor as a peripheral marker for the action mechanism of antidepressants. Neuropsychobiology 2008;57:194-199. https://doi.org/10.1159/000149817
- Piccinni A, Marazziti D, Catena M, Domenici L, Del Debbio A, Bianchi C, et al. Plasma and serum brain-derived neurotrophic factor (BDNF) in depressed patients during 1 year of antidepressant treatments. J Affect Disord 2008;105:279-283. https://doi.org/10.1016/j.jad.2007.05.005
- Dwivedi Y, Rizavi HS, Conley RR, Roberts RC, Tamminga CA, Pandey GN. Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects. Arch Gen Psychiatry 2003;60:804-815. https://doi.org/10.1001/archpsyc.60.8.804
- Pandey GN, Ren X, Rizavi HS, Conley RR, Roberts RC, Dwivedi Y. Brain-derived neurotrophic factor and tyrosine kinase B receptor signalling in post-mortem brain of teenage suicide victims. Int J Neuropsychopharmacol 2008;11:1047-1061. https://doi.org/10.1017/S1461145708009000
- Ernst C, Deleva V, Deng X, Sequeira A, Pomarenski A, Klempan T, et al. Alternative splicing, methylation state, and expression profile of tropomyosin-related kinase B in the frontal cortex of suicide completers. Arch Gen Psychiatry 2009;66:22-32. https://doi.org/10.1001/archpsyc.66.1.22
- Dwivedi Y, Rizavi HS, Zhang H, Mondal AC, Roberts RC, Conley RR, et al. Neurotrophin receptor activation and expression in human postmortem brain: effect of suicide. Biol Psychiatry 2009;65:319-328. https://doi.org/10.1016/j.biopsych.2008.08.035
- Deveci A, Aydemir O, Taskin O, Taneli F, Esen-Danaci A. Serum BDNF levels in suicide attempters related to psychosocial stressors: a comparative study with depression. Neuropsychobiology 2007;56:93-97. https://doi.org/10.1159/000111539
- Kim YK, Lee HP, Won SD, Park EY, Lee HY, Lee BH, et al. Low plasma BDNF is associated with suicidal behavior in depression. Prog Neuropsychopharmacol Biol Psychiatry 2007;31:78-85. https://doi.org/10.1016/j.pnpbp.2006.06.024
- Dawood T, Anderson J, Barton D, Lambert E, Esler M, Hotchkin E, et al. Reduced overflow of BDNF from the brain is linked with suicide risk in depressive illness. Mol Psychiatry 2007;12:981-983. https://doi.org/10.1038/sj.mp.4002059
- Malcangio M, Lessmann V. A common thread for pain and memory synapses? Brain-derived neurotrophic factor and trkB receptors. Trends Pharmacol Sci 2003;24:116-121. https://doi.org/10.1016/S0165-6147(03)00025-7
Cited by
- Recent advances in psychoneuroimmunology: Inflammation in psychiatric disorders vol.2, pp.2, 2011, https://doi.org/10.2478/s13380-011-0019-0
- Rapid antidepressant changes with sleep deprivation in major depressive disorder are associated with changes in vascular endothelial growth factor (VEGF): A pilot study vol.86, pp.1, 2010, https://doi.org/10.1016/j.brainresbull.2011.06.003
- Multiple antidepressant potential modes of action of curcumin: a review of its anti-inflammatory, monoaminergic, antioxidant, immune-modulating and neuroprotective effects vol.26, pp.12, 2010, https://doi.org/10.1177/0269881112458732
- Increased plasma VEGF levels in major depressive or manic episodes in patients with mood disorders vol.136, pp.1, 2010, https://doi.org/10.1016/j.jad.2011.07.021
- Beyond the monoaminergic hypothesis: neuroplasticity and epigenetic changes in a transgenic mouse model of depression vol.367, pp.1601, 2010, https://doi.org/10.1098/rstb.2012.0212
- Ethanol extracts from Hemerocallis citrina attenuate the decreases of brain-derived neurotrophic factor, TrkB levels in rat induced by corticosterone administration vol.144, pp.2, 2010, https://doi.org/10.1016/j.jep.2012.09.016
- Antidepressant therapy in epilepsy: can treating the comorbidities affect the underlying disorder? : Antidepressant treatment in epilepsy vol.168, pp.7, 2010, https://doi.org/10.1111/bph.12052
- Neurobiology of Major Depressive Disorder vol.2013, pp.None, 2010, https://doi.org/10.1155/2013/873278
- NESS06SM reduces body weight with an improved profile relative to SR141716A vol.74, pp.None, 2010, https://doi.org/10.1016/j.phrs.2013.06.001
- Short-term effects of escitalopram on regional brain function in first-episode drug-naive patients with major depressive disorder assessed by resting-state functional magnetic resonance imaging vol.44, pp.7, 2014, https://doi.org/10.1017/s0033291713002031
- Controversies about a common etiology for eating and mood disorders vol.5, pp.None, 2010, https://doi.org/10.3389/fpsyg.2014.01205
- β-Asarone Reverses Chronic Unpredictable Mild Stress-Induced Depression-Like Behavior and Promotes Hippocampal Neurogenesis in Rats vol.19, pp.5, 2014, https://doi.org/10.3390/molecules19055634
- Antidepressant Activity of Astilbin: Involvement of Monoaminergic Neurotransmitters and BDNF Signal Pathway vol.37, pp.6, 2014, https://doi.org/10.1248/bpb.b13-00968
- A Possible Link between Food and Mood: Dietary Impact on Gut Microbiota and Behavior in BALB/c Mice vol.9, pp.8, 2014, https://doi.org/10.1371/journal.pone.0103398
- Early-life adversity and adolescent depression: mechanisms involving the ventral striatum vol.20, pp.4, 2010, https://doi.org/10.1017/s1092852914000674
- Feasibility of an Exercise Program for Older Depressive Inpatients : A Pilot Study vol.28, pp.4, 2010, https://doi.org/10.1024/1662-9647/a000134
- Psychiatric Disorders and Polyphenols: Can They Be Helpful in Therapy? vol.2015, pp.None, 2010, https://doi.org/10.1155/2015/248529
- The mechanisms by which antidepressants may reduce coronary heart disease risk vol.15, pp.None, 2010, https://doi.org/10.1186/s12872-015-0074-5
- Angelica gigas ameliorate depression-like symptoms in rats following chronic corticosterone injection vol.15, pp.None, 2010, https://doi.org/10.1186/s12906-015-0746-9
- Schizophrenia and Depression Co-Morbidity: What We have Learned from Animal Models vol.6, pp.None, 2015, https://doi.org/10.3389/fpsyt.2015.00013
- Enduring good memories of infant trauma: Rescue of adult neurobehavioral deficits via amygdala serotonin and corticosterone interaction vol.112, pp.3, 2010, https://doi.org/10.1073/pnas.1416065112
- Zinc monotherapy increases serum brain-derived neurotrophic factor (BDNF) levels and decreases depressive symptoms in overweight or obese subjects: A double-blind, randomized, placebo-controlled trial vol.18, pp.4, 2015, https://doi.org/10.1179/1476830513y.0000000105
- Protective Effects of Silibinin and Its Possible Mechanism of Action in Mice Exposed to Chronic Unpredictable Mild Stress vol.23, pp.3, 2015, https://doi.org/10.4062/biomolther.2014.138
- Neurobiological mechanisms of repetitive transcranial magnetic stimulation of the dorsolateral prefrontal cortex in depression: a systematic review vol.45, pp.16, 2010, https://doi.org/10.1017/s0033291715001609
- Crosstalk between endocannabinoid and immune systems: a potential dysregulation in depression? vol.233, pp.None, 2010, https://doi.org/10.1007/s00213-015-4105-9
- Antidepressant-like effects of standardized gypenosides: involvement of brain-derived neurotrophic factor signaling in hippocampus vol.233, pp.17, 2010, https://doi.org/10.1007/s00213-016-4357-z
- Criticism in the Self, Brain, Relationships, and Social Structure: Implications for Psychodynamic Psychiatry vol.44, pp.3, 2016, https://doi.org/10.1521/pdps.2016.44.3.395
- Molecular Neurobiology and Promising New Treatment in Depression vol.17, pp.3, 2010, https://doi.org/10.3390/ijms17030381
- Deconstructing the Iboga Alkaloid Skeleton: Potentiation of FGF2-induced Glial Cell Line-Derived Neurotrophic Factor Release by a Novel Compound vol.11, pp.1, 2010, https://doi.org/10.1021/acschembio.5b00678
- Antidepressant-like effect of Ikwitang involves modulation of monoaminergic systems vol.13, pp.3, 2010, https://doi.org/10.3892/mmr.2016.4809
- Possible involvement of the JAK/STAT signaling pathway in N-acetylcysteine-mediated antidepressant-like effects vol.241, pp.5, 2010, https://doi.org/10.1177/1535370215619707
- MicroRNA Profiling in the Medial and Lateral Habenula of Rats Exposed to the Learned Helplessness Paradigm: Candidate Biomarkers for Susceptibility and Resilience to Inescapable Shock vol.11, pp.8, 2010, https://doi.org/10.1371/journal.pone.0160318
- Side effect profile similarities shared between antidepressants and immune-modulators reveal potential novel targets for treating major depressive disorders vol.17, pp.1, 2016, https://doi.org/10.1186/s40360-016-0090-9
- Pharmacogenetic studies: a tool to improve antidepressant therapy vol.31, pp.4, 2010, https://doi.org/10.1515/dmpt-2016-0019
- Pharmacogenetic studies: a tool to improve antidepressant therapy vol.31, pp.4, 2010, https://doi.org/10.1515/dmpt-2016-0019
- A Place for Sexual Dysfunctions in an Empirical Taxonomy of Psychopathology vol.54, pp.4, 2010, https://doi.org/10.1080/00224499.2016.1269306
- Overweight and Obesity Associated with Higher Depression Prevalence in Adults: A Systematic Review and Meta-Analysis vol.36, pp.3, 2010, https://doi.org/10.1080/07315724.2016.1261053
- Brain-Derived Neurotrophic Factor, Depression, and Physical Activity: Making the Neuroplastic Connection vol.2017, pp.None, 2010, https://doi.org/10.1155/2017/7260130
- The Mechanism of Depression in Adolescence Has a Higher Morbidity vol.7, pp.7, 2010, https://doi.org/10.12677/ap.2017.77114
- Towards Better Understanding of the Pathogenesis of Neuronal Respiratory Network in Sudden Perinatal Death vol.8, pp.None, 2017, https://doi.org/10.3389/fneur.2017.00320
- Meta-analyses of comparative efficacy of antidepressant medications on peripheral BDNF concentration in patients with depression vol.12, pp.2, 2010, https://doi.org/10.1371/journal.pone.0172270
- The Relationship between Fatty Acids and Different Depression-Related Brain Regions, and Their Potential Role as Biomarkers of Response to Antidepressants vol.9, pp.3, 2010, https://doi.org/10.3390/nu9030298
- Serum lipids and brain-derived neurotrophic factor in a cross-section of male students with symptoms of depression at a university in Iran: an observational study vol.11, pp.5, 2017, https://doi.org/10.1515/abm-2018-0016
- Determinants of neonatal brain-derived neurotrophic factor and association with child development vol.29, pp.4, 2010, https://doi.org/10.1017/s0954579417000414
- Relationship Between Brain-Derived Neurotrofic Factor (Bdnf) and Sleep on Depression: A Critical Review vol.13, pp.None, 2010, https://doi.org/10.2174/1745017901713010213
- Sex Differences in Risk for Alzheimer’s Disease Related to Neurotrophin Gene Polymorphisms: The Cache County Memory Study vol.72, pp.12, 2010, https://doi.org/10.1093/gerona/glx092
- Alleviative effects of fluoxetine on depressive - like behaviors by epigenetic regulation of BDNF gene transcription in mouse model of post-stroke depression vol.7, pp.None, 2017, https://doi.org/10.1038/s41598-017-13929-5
- The combination of escitalopram and aripiprazole: Investigation of psychomotor effects in rats vol.31, pp.12, 2010, https://doi.org/10.1177/0269881117732515
- Glucose Can Epigenetically Alter the Gene Expression of Neurotrophic Factors in the Murine Brain Cells vol.55, pp.4, 2018, https://doi.org/10.1007/s12035-017-0578-3
- Inflammatory Profiles in Depressed Adolescents Treated with Fluoxetine: An 8-Week Follow-up Open Study vol.2018, pp.None, 2010, https://doi.org/10.1155/2018/4074051
- Growth of Triple Negative and Progesterone Positive Breast Cancer Causes Oxidative Stress and Down-Regulates Neuroprotective Transcription Factor NPAS4 and NPAS4-Regulated Genes in Hippocampal Tissues vol.9, pp.None, 2018, https://doi.org/10.3389/fgene.2018.00058
- Psychotherapy and Genetic Neuroscience: An Emerging Dialog vol.9, pp.None, 2010, https://doi.org/10.3389/fgene.2018.00257
- The Immediate Early Gene Egr3 Is Required for Hippocampal Induction of Bdnf by Electroconvulsive Stimulation vol.12, pp.None, 2018, https://doi.org/10.3389/fnbeh.2018.00092
- Chronic Hippocampal Abnormalities and Blunted HPA Axis in an Animal Model of Repeated Unpredictable Stress vol.12, pp.None, 2010, https://doi.org/10.3389/fnbeh.2018.00150
- Sex-Dependent Effects of Environmental Enrichment on Spatial Memory and Brain-Derived Neurotrophic Factor (BDNF) Signaling in a Developmental “Two-Hit” Mouse Model Combining BDNF Haploinsufficiency vol.12, pp.None, 2010, https://doi.org/10.3389/fnbeh.2018.00227
- Selanylimidazopyridine Prevents Lipopolysaccharide-Induced Depressive-Like Behavior in Mice by Targeting Neurotrophins and Inflammatory/Oxidative Mediators vol.12, pp.None, 2010, https://doi.org/10.3389/fnins.2018.00486
- Selective Depletion of CREB in Serotonergic Neurons Affects the Upregulation of Brain-Derived Neurotrophic Factor Evoked by Chronic Fluoxetine Treatment vol.12, pp.None, 2010, https://doi.org/10.3389/fnins.2018.00637
- Effects of prenatal alcohol exposure (PAE): insights into FASD using mouse models of PAE vol.96, pp.2, 2010, https://doi.org/10.1139/bcb-2017-0280
- Predictors of Response to Ketamine in Treatment Resistant Major Depressive Disorder and Bipolar Disorder vol.15, pp.4, 2010, https://doi.org/10.3390/ijerph15040771
- Lasting changes induced by mild alcohol exposure during embryonic development in BDNF, NCAM and synaptophysin‐positive neurons quantified in adult zebrafish vol.47, pp.12, 2018, https://doi.org/10.1111/ejn.13975
- Stress Biomarkers in Biological Fluids and Their Point-of-Use Detection vol.3, pp.10, 2010, https://doi.org/10.1021/acssensors.8b00726
- Peritoneal endometriosis induces time-related depressive- and anxiety-like alterations in female rats: involvement of hippocampal pro-oxidative and BDNF alterations vol.34, pp.3, 2010, https://doi.org/10.1007/s11011-019-00397-1
- What do DNA methylation studies tell us about depression? A systematic review vol.9, pp.1, 2010, https://doi.org/10.1038/s41398-019-0412-y
- Alterations in the Levels of Growth Factors in Adolescents with Major Depressive Disorder: A Longitudinal Study during the Treatment with Fluoxetine vol.2019, pp.None, 2010, https://doi.org/10.1155/2019/9130868
- Decoding the Mechanism of Action of Rapid-Acting Antidepressant Treatment Strategies: Does Gender Matter? vol.20, pp.4, 2010, https://doi.org/10.3390/ijms20040949
- The Low Molecular Weight Brain-derived Neurotrophic Factor Mimetics with Antidepressant-like Activity vol.25, pp.6, 2010, https://doi.org/10.2174/1381612825666190329122852
- Low serum brain-derived neurotrophic factor is associated with suicidal ideation in major depressive disorder vol.273, pp.None, 2019, https://doi.org/10.1016/j.psychres.2019.01.013
- Direct and indirect evidences of BDNF and NGF as key modulators in depression: role of antidepressants treatment vol.129, pp.3, 2019, https://doi.org/10.1080/00207454.2018.1527328
- Differential associations of depression‐related phenotypes with cardiometabolic risks: Polygenic analyses and exploring shared genetic variants and pathways vol.36, pp.4, 2010, https://doi.org/10.1002/da.22861
- Effect of probiotic interventions on depressive symptoms: A narrative review evaluating systematic reviews vol.73, pp.4, 2010, https://doi.org/10.1111/pcn.12804
- Stress – (self) eating: Epigenetic regulation of autophagy in response to psychological stress vol.286, pp.13, 2010, https://doi.org/10.1111/febs.14826
- Elucidation of the Molecular Mechanism Underlying Lippia citriodora(Lim.)-Induced Relaxation and Anti-Depression vol.20, pp.14, 2010, https://doi.org/10.3390/ijms20143556
- Linking unfolded protein response to inflammation and depression: potential pathologic and therapeutic implications vol.24, pp.7, 2010, https://doi.org/10.1038/s41380-018-0241-z
- The chemokine CXCL1 and its receptor CXCR2 contribute to chronic stress‐induced depression in mice vol.33, pp.8, 2010, https://doi.org/10.1096/fj.201802359rr
- Paeoniflorin attenuates impairment of spatial learning and hippocampal long-term potentiation in mice subjected to chronic unpredictable mild stress vol.236, pp.9, 2010, https://doi.org/10.1007/s00213-019-05257-5
- Off-label Antidepressant Use for Treatment and Management of Chronic Pain: Evolving Understanding and Comprehensive Review vol.23, pp.9, 2010, https://doi.org/10.1007/s11916-019-0803-z
- Neuroprotective Benefits of Antidepressants in Multiple Sclerosis: Are We Missing the Mark? vol.31, pp.4, 2010, https://doi.org/10.1176/appi.neuropsych.18070164
- Behavioural characterisation of chronic unpredictable stress based on ethologically relevant paradigms in rats vol.9, pp.1, 2010, https://doi.org/10.1038/s41598-019-53624-1
- The Impact of Social and Behavioral Factors on Reproducibility in Terrestrial Vertebrate Models vol.60, pp.2, 2019, https://doi.org/10.1093/ilar/ilaa005
- Flaxseed oil supplementation on severity of depression and brain-derived neurotrophic factor: a randomized, double blind placebo controlled clinical trial vol.23, pp.1, 2010, https://doi.org/10.1080/10942912.2020.1812639
- Among Adolescents, BDNF and Pro-BDNF Lasting Changes with Alcohol Use Are Stage Specific vol.2020, pp.None, 2010, https://doi.org/10.1155/2020/3937627
- FGF21 Attenuated LPS-Induced Depressive-Like Behavior via Inhibiting the Inflammatory Pathway vol.11, pp.None, 2010, https://doi.org/10.3389/fphar.2020.00154
- New Insights on the Role of N 6 -Methyladenosine RNA Methylation in the Physiology and Pathology of the Nervous System vol.7, pp.None, 2010, https://doi.org/10.3389/fmolb.2020.555372
- Curcumin in Depression: Potential Mechanisms of Action and Current Evidence—A Narrative Review vol.11, pp.None, 2010, https://doi.org/10.3389/fpsyt.2020.572533
- Analyzing the genes and pathways related to major depressive disorder via a systems biology approach vol.10, pp.2, 2010, https://doi.org/10.1002/brb3.1502
- The Effect of Probiotic Intervention in Ameliorating the Altered Central Nervous System Functions in Neurological Disorders: A Review vol.14, pp.None, 2020, https://doi.org/10.2174/1874285802014010018
- Brain‐derived neurotrophic factor and post‐stroke depression vol.98, pp.3, 2010, https://doi.org/10.1002/jnr.24510
- Is There a Future for PPARs in the Treatment of Neuropsychiatric Disorders? vol.25, pp.5, 2020, https://doi.org/10.3390/molecules25051062
- Inflammatory, Structural, and Pain Biochemical Biomarkers May Reflect Radiographic Disc Space Narrowing: The Johnston County Osteoarthritis Project vol.38, pp.5, 2010, https://doi.org/10.1002/jor.24534
- The Novel Role of PPAR Alpha in the Brain: Promising Target in Therapy of Alzheimer’s Disease and Other Neurodegenerative Disorders vol.45, pp.5, 2010, https://doi.org/10.1007/s11064-020-02993-5
- Cellular mechanisms and molecular signaling pathways in stress-induced anxiety, depression, and blood-brain barrier inflammation and leakage vol.28, pp.3, 2010, https://doi.org/10.1007/s10787-020-00712-8
- Polyphenols selectively reverse early-life stress-induced behavioural, neurochemical and microbiota changes in the rat vol.116, pp.None, 2010, https://doi.org/10.1016/j.psyneuen.2020.104673
- State-of-the-Art: Inflammatory and Metabolic Markers in Mood Disorders vol.10, pp.6, 2020, https://doi.org/10.3390/life10060082
- Peripheral Biomarkers in DSM-5 Anxiety Disorders: An Updated Overview vol.10, pp.8, 2010, https://doi.org/10.3390/brainsci10080564
- Neuroinflammation and microglia/macrophage phenotype modulate the molecular background of post-stroke depression: A literature review vol.20, pp.3, 2010, https://doi.org/10.3892/etm.2020.8933
- Dance and Parkinson's: Biological perspective and rationale vol.1, pp.2, 2010, https://doi.org/10.1002/lim2.15
- Folic acid ameliorates depression-like behaviour in a rat model of chronic unpredictable mild stress vol.21, pp.1, 2020, https://doi.org/10.1186/s12868-020-0551-3
- Asparagus cochinchinensis extract ameliorates menopausal depression in ovariectomized rats under chronic unpredictable mild stress vol.20, pp.1, 2010, https://doi.org/10.1186/s12906-020-03121-0
- Rapid and long-lasting antidepressant-like effects of ketamine and their relationship with the expression of brain enzymes, BDNF, and astrocytes vol.54, pp.2, 2010, https://doi.org/10.1590/1414-431x202010107
- Comparison of Brain-derived Neurotrophic Factor Level in Depressed Patients Treated with Fluoxetine and Sertraline vol.9, pp.t3, 2010, https://doi.org/10.3889/oamjms.2021.6348
- Mechanism of Intermittent Theta-Burst Stimulation in Synaptic Pathology in the Prefrontal Cortex in an Antidepressant-Resistant Depression Rat Model vol.31, pp.1, 2021, https://doi.org/10.1093/cercor/bhaa244
- Plasma BDNF concentrations and the antidepressant effects of six ketamine infusions in unipolar and bipolar depression vol.9, pp.None, 2010, https://doi.org/10.7717/peerj.10989
- Blood Brain-Derived Neurotrophic Factor (BDNF) and Major Depression: Do We Have a Translational Perspective? vol.15, pp.None, 2010, https://doi.org/10.3389/fnbeh.2021.626906
- Hederagenin Protects PC12 Cells Against Corticosterone-Induced Injury by the Activation of the PI3K/AKT Pathway vol.12, pp.None, 2021, https://doi.org/10.3389/fphar.2021.712876
- The anti-inflammatory role of SSRI and SNRI in the treatment of depression: a review of human and rodent research studies vol.29, pp.1, 2010, https://doi.org/10.1007/s10787-020-00777-5
- Cardiac glycosaminoglycans and structural alterations during chronic stress-induced depression-like behavior in mice vol.320, pp.5, 2021, https://doi.org/10.1152/ajpheart.00635.2020
- Correlations between serum BDNF levels and neurodevelopmental outcomes in infants of mothers with gestational diabetes vol.62, pp.3, 2010, https://doi.org/10.1016/j.pedneo.2020.12.012
- Potential depression and antidepressant-response biomarkers in human lymphoblast cell lines from treatment-responsive and treatment-resistant subjects: roles of SSRIs and omega-3 polyunsaturated fatty vol.26, pp.6, 2010, https://doi.org/10.1038/s41380-020-0724-6
- Comparative Analysis of Pathobiochemical Changes in Major Depression and Post-Traumatic Stress Disorder vol.86, pp.6, 2021, https://doi.org/10.1134/s0006297921060109
- Changes of BDNF exon IV DNA methylation are associated with methamphetamine dependence vol.13, pp.12, 2010, https://doi.org/10.2217/epi-2020-0463
- Maternal diabetes-induced alterations in the expression of brain-derived neurotrophic factor in the developing rat hippocampus vol.114, pp.None, 2021, https://doi.org/10.1016/j.jchemneu.2021.101946
- Allopregnanolone in mood disorders: Mechanism and therapeutic development vol.169, pp.None, 2021, https://doi.org/10.1016/j.phrs.2021.105682
- The Effect of Blockade of Androgen Receptors by Flutamide on Learning and Memory, Synaptic Plasticity and Behavioral Performances: A Review Study vol.15, pp.4, 2010, https://doi.org/10.1134/s1990519x21040088
- The long-term bio-behavioural effects of juvenile sildenafil treatment in Sprague-Dawley versus flinders sensitive line rats vol.33, pp.4, 2010, https://doi.org/10.1017/neu.2021.4
- The PPARg System in Major Depression: Pathophysiologic and Therapeutic Implications vol.22, pp.17, 2010, https://doi.org/10.3390/ijms22179248
- Potential biomarkers of major depression diagnosis and chronicity vol.16, pp.9, 2010, https://doi.org/10.1371/journal.pone.0257251
- Genotype-expression interactions for BDNF across human brain regions vol.22, pp.1, 2021, https://doi.org/10.1186/s12864-021-07525-1
- Emerging Role of Flavonoids as the Treatment of Depression vol.11, pp.12, 2010, https://doi.org/10.3390/biom11121825
- Psychobiotics as treatment for anxiety, depression, and related symptoms: a systematic review vol.24, pp.12, 2010, https://doi.org/10.1080/1028415x.2019.1701220
- Dietary Intake of Flavonoids and Carotenoids Is Associated with Anti-Depressive Symptoms: Epidemiological Study and In Silico-Mechanism Analysis vol.11, pp.1, 2010, https://doi.org/10.3390/antiox11010053
- Cortisol and development of depression in adolescence and young adulthood – a systematic review and meta-analysis vol.136, pp.None, 2010, https://doi.org/10.1016/j.psyneuen.2021.105625