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Recent Progression in Sarcopenia and Sarcopenic Obesity

근감소증과 근감소성 비만

  • Jang, Hak-Chul (Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine)
  • 장학철 (서울대학교 의과대학 내과학교실, 분당서울대학교병원 내과)
  • Published : 2011.03.31

Abstract

One of the important changes of body composition with ageing is the increase of fat mass and visceral fat and the decrease of muscle mass and strength. Sarcopenia, the age-related decrease in skeletal muscle mass, is associated with functional disability, falls, and mortality. Recent studies found that older people with low skeletal muscle mass and obesity (sarcopenic obesity) have a higher risk for cardiovascular and metabolic diseases. However, a consensus of the definition of sarcopenia is lacking in clinical practice. The reported prevalence of sarcopenia and sarcopenia in Koreans is a wide range. This may be due to differences in study population and diagnostic criteria for sarcopenia. The European Working Group on Sarcopenia in Older People proposed a clinical definition and diagnostic criteria for sarcopenia. These diagnostic criteria include the presence of both low muscle mass and low muscle function (strength or performance). Further studies for the clinical application of newly developed criteria for sarcopenia are needed.

노화에 따른 주요한 체성분의 변화의 하나가 근육량 및 근력의 감소이며, 체지방 및 복강 내 지방의 증가이다. 근육량과 근력의 감소는 30대부터 시작되며, 노인에서 근감소증과 근감소성 비만은 낙상, 기능장애, 삶의 질 저하, 사망률의 증가 등을 증가시키게 될 뿐만 아니라, 심혈관질환, 대사장애의 위험을 증가시키게 된다. 또 이로 인한 사회-경제적 부담은 노인 인구의 증가와 함께 큰 문제를 야기할 것이다. 현재 한국을 비롯한 아시안 노인에서 근감소증 및 근감소성 비만의 연구는 제한되어 있을 뿐만 아니라, 역학 연구도 부족하다. 또 근감소증의 정의 및 진단기준도 세계적으로 널리 통용되는 것이 없어, 인종간의 비교도 어려운 실정이다. EWGSOP에서 제시한 근감소증의 보완된 진단은 이러한 점에서 고려할 만하다. 이를 계기로 국내에서도 근감소증의 많은 연구가 진행되기를 기대한다.

Keywords

References

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