Asian Pacific Journal of Cancer Prevention

Asian Pacific Journal of Cancer Prevention (아시아태평양암예방학회)
권호 표지

A Case-control Study of Risk Factors for Lung Cancer in Mumbai, India

Ganesh, B;Sushama, S;Monika, S;Suvarna, P

  • Published : 20110200
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Abstract

In the year 2010, it is estimated that nearly 1.35 million new cases and 1.18 million deaths with lung cancer occurred. In India, among males, lung cancer rates vary across the country which has encouraged us to conduct a case-control study to study the risk factors. The present unmatched hospital-based case-control study conducted at Tata Memorial Hospital included subjects registered between the years 1997-99. There were 408 lung 'cancer cases' and 1383 'normal controls. Data on age, tobacco habits, occupational history, dietary factors, tea, coffee were collected by the social investigators. Univariate and regression analysis were applied for obtaining the odds ratio for risk factors. In the study, cigarette smoking (OR=5.2) and bidi smoking (OR=8.3), as well as alcohol consumption (OR=1.8), demonstrated dose-response relationships with lung cancer risk. Among the dietary items, only red-meat consumption showed 2.2-fold significant excess risk. Consumption of milk showed a 60% reduction in risk; while coffee showed a 2-fold excess risk for lung cancer. In addition, exposure to use of pesticides showed a 2.5-fold significant excess risk for lung cancer.

Keywords

References

  1. Bae J, Gwack J, Park SK, et al (2007). Cigarette smoking, alcohol consumption, tuberculosis and risk of lung cancer: the Korean multi-center cancer cohort study. J Prev Med Pub Hlth, 40, 321-8. https://doi.org/10.3961/jpmph.2007.40.4.321
  2. Baker JA, McCann SE, Reid ME, et al (2005). Associations between black tea and coffee consumption and risk of lung cancer among current and former smokers. Nutr Cancer, 52, 15-21. https://doi.org/10.1207/s15327914nc5201_2
  3. Bandera EV, Freudenheim JL, Vena JE (2001). Alcohol consumption and lung cancer: a review of the epidemiologic evidence. Cancer Epidemiol Biomarkers Prev, 10, 813-21.
  4. Dinham B (2005). Prolonged exposure to some agricultural pesticides may increase the risk of lung cancer in agricultural worker. Evidence-Based Healthcare Pub Hlth, 9, 203-5. https://doi.org/10.1016/j.ehbc.2005.03.029
  5. Barthel E (1981). Increased risk of lung cancer in pesticideexposed male agricultural workers. J Toxicol Environ Health, 8, 1027-40. https://doi.org/10.1080/15287398109530135
  6. De Stefani E, Boffetta P, Deneo, et al (2009). Meat intake, meat mutagens and risk of lung cancer in Uruguayan men. Cancer Causes Control, 20, 1635-43. https://doi.org/10.1007/s10552-009-9411-2
  7. Ferlay J, Shin HR, Bray F, Forman D, Mathers C and Parkin DM (2010). GLOBOCAN 2008. Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 10 [Internet]. Lyon, France: International Agency for Research on Cancer;. Available from: http://globocan.iarc.fr
  8. Ger LP, Liou SH, Shen CY, Kao SJ, Chen KT (1992). Risk factors of lung cancer. J Formos Med Assoc, 91 Suppl 3, S222-31.
  9. Jo L Freudenheim, John Ritz, Stephanie A Smith-Warner, et al (2005). Alcohol consumption and risk of lung cancer: a pooled analysis of cohort studies. Am J Clin Nutr, 82, 657-67. https://doi.org/10.1093/ajcn/82.3.657
  10. Kurkure AP, Yeole BB, Koyande SS (2010). Cancer Incidence and mortality in greater Mumbai 2006- Mumbai cancer registry; Indian cancer society, Mumbai, India
  11. Li Q, Kakizaki M, Kuriyama S, et al (2008). Green tea consumption and lung cancer risk: the Ohsaki study. Br J Cancer, 99, 1179-84. https://doi.org/10.1038/sj.bjc.6604645
  12. Liu YW, Chen JQ, Sun XR, Yang J, Liu Y, Chen WH. (2008). A test of screening to predict lung cancer among dust-exposed tin miners with sputum imaging cytometry. Chin J Ind Hyg Occup Exp, 26, 203-7
  13. Marchand JL, Luce D, Goldberg P, et al(2002). Dietary factors and the risk of lung cancer in New Caledonia (South Pacific). Nutr Cancer, 42, 18-24 https://doi.org/10.1207/S15327914NC421_3
  14. Mettlin C (1989). Milk drinking, other beverage habits, and lung cancer risk. Int J Cancer, 43, 608-12. https://doi.org/10.1002/ijc.2910430412
  15. NCRP (2007) Two-year Report of the Population Based Cancer Registries- 2004-2005. National Cancer Registry Programme, Indian Council of Medical Research, Bangalore, India.
  16. NFHS(2007). International Institute for Population Sciences (IIPS) and Macro International. National Family Health Survey (NFHS-3), 2005-06: India: Volume I. Mumbai : IIPS.
  17. Notani P, Sanghvi LD (1974). A retrospective study of lung cancer in Bombay. Br J Cancer, 29, 477-82. https://doi.org/10.1038/bjc.1974.100
  18. Notani PN, Shah P, Jayant K, Balakrishnan V (1993). Occupation and cancers of the lung and bladder: a case-control study in Bombay. Int J Epid, 22, 185-91. https://doi.org/10.1093/ije/22.2.185
  19. Sanghvi LD, Rao KCM, Khanolkar VR(1955). Smoking and chewing of tobacco in relation to cancer of the upper alimentary tract. Brit Med J, 1, 1111-4 . https://doi.org/10.1136/bmj.1.4922.1111
  20. Tasevska N, Sinha R, Kipnis V, et al (2009). A prospective study of meat, cooking methods, meat mutagens, heme iron, and lung cancer risks. Am J Clin Nutr, 89, 1884-94. https://doi.org/10.3945/ajcn.2008.27272