Toxicological Research

Korean Society of Toxicology & Korea Environmental Mutagen Society (한국독성학회)
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Possible Health Effects of Caffeinated Coffee Consumption on Alzheimer's Disease and Cardiovascular Disease

  • You, Dong-Chul (College of Health Sciences, Korea University) ;
  • Kim, Young-Soon (College of Health Sciences, Korea University) ;
  • Ha, Ae-Wha (Research Institute of Health Science, College of Health Science, Korea University) ;
  • Lee, Yu-Na (College of Health Sciences, Korea University) ;
  • Kim, Soo-Min (College of Natural Sciences, SangMyoung University) ;
  • Kim, Chun-Heum (College of Medicine, InHa University) ;
  • Lee, Seung-Ha (College of Health Sciences, Korea University) ;
  • Choi, Dal-Woong (College of Health Sciences, Korea University) ;
  • Lee, Jae-Min (College of Health Sciences, Korea University)
  • Received : 2011.01.04
  • Accepted : 2011.01.25
  • Published : 2011.03.01
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Abstract

Coffee has been known to have both beneficial and harmful effects upon health. Coffee is one of the most widely consumed beverages, worldwide. Dementia/Alzheimer's disease (AD) and cardiovascular disease (CVD) are public health problems that are rapidly increasing in the aging population. Due to the high consumption of coffee, even small effects on an individual's health could have a large effect on public health. The aim of this review article is to provide an overview of previously published studies of coffee consumption on health. Herein, we focus on epidemiological and experimental findings to investigate whether coffee-drinking habits, and/or the quantity of coffee consumption, have any relationship to CVD, dementia/AD, and other chronic diseases. Although the underlying mechanisms are not fully understood, when comparing coffee drinkers with non-drinkers, moderate doses of caffeine showed protective effects against CVD and AD. We hypothesized that caffeine may be a novel therapy to treat CVD and dementia/AD.

Keywords

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