Journal of Gastric Cancer

The Korean Gastric Cancer Association (대한위암학회)
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Gastric Cancer Epidemiology in Korea

  • Shin, Ae-Sun (Cancer Epidemiology Branch, National Cancer Center) ;
  • Kim, Jeong-Seon (Cancer Epidemiology Branch, National Cancer Center) ;
  • Park, So-Hee (Cancer Registration and Statistics Branch, National Cancer Center)
  • Received : 2011.08.01
  • Accepted : 2011.08.16
  • Published : 2011.09.30
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Abstract

Gastric cancer has been the most commonly diagnosed cancer in Korea although the age-standardized mortality and incidence has decreased gradually during last two decades. $Helicobacter$ $pylori$ infection and cigarette smoking are well-established risk factors, and the role of dietary factors, such as salted foods, fresh vegetables and fruits, soy foods, and processed or grilled meats on gastric carcinogenesis has been suggested. In this review, we review national and international gastric cancer statistics, studies on environmental risk factors conducted in the Korean population, and gastric cancer screening activities.

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References

  1. http://globocan.iarc.fr/Accessed July 29, 2011.
  2. Shin A, Park S, Shin HR, Park EH, Park SK, Oh JK, et al. Population attributable fraction of infection-related cancers in Korea. Ann Oncol 2011;22:1435-1442. https://doi.org/10.1093/annonc/mdq592
  3. Jung KW, Park S, Kong HJ, Won YJ, Lee JY, Park EC, et al. Cancer statistics in Korea: incidence, mortality, survival, and prevalence in 2008. Cancer Res Treat 2011;43:1-11. https://doi.org/10.4143/crt.2011.43.1.1
  4. http://www.kosis.kr/Accessed July 21, 2011
  5. Jung KW, Park S, Won YJ, Kong HJ, Lee JY, Park EC, et al. Prediction of cancer incidence and mortality in Korea, 2011. Cancer Res Treat 2011;43:12-18 https://doi.org/10.4143/crt.2011.43.1.12
  6. World Health Organization International Agency for Research on Cancer. Schistosomes, Liver Flukes and Helicobacter pylori. In: IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. Lyon: International Agency for Research on Cancer, 1994.
  7. Bouvard V, Baan R, Straif K, Grosse Y, Secretan B, El Ghissassi F, et al; WHO International Agency for Research on Cancer Monograph Working Group. A review of human carcinogens-- Part B: biological agents. Lancet Oncol 2009;10:321-322. https://doi.org/10.1016/S1470-2045(09)70096-8
  8. Helicobacter and Cancer Collaborative Group. Gastric cancer and Helicobacter pylori: a combined analysis of 12 case control studies nested within prospective cohorts. Gut 2001;49:347- 353. https://doi.org/10.1136/gut.49.3.347
  9. Chang WK, Kim HY, Kim DJ, Lee J, Park CK, Yoo JY, et al. Association between Helicobacter pylori infection and the risk of gastric cancer in the Korean population: prospective casecontrolled study. J Gastroenterol 2001;36:816-822. https://doi.org/10.1007/s005350170003
  10. Cho SJ, Choi IJ, Kim CG, Lee JY, Kook MC, Seong MW, et al. Helicobacter pylori seropositivity is associated with gastric cancer regardless of tumor subtype in Korea. Gut Liver 2010;4:466-474. https://doi.org/10.5009/gnl.2010.4.4.466
  11. Kim DS, Lee MS, Kim YS, Kim DH, Bae JM, Shin MH, et al. Effect modification by vitamin C on the relation between gastric cancer and Helicobacter pylori . Eur J Epidemiol 2005;20:67-71. https://doi.org/10.1007/s10654-004-1027-y
  12. Lee SA, Kang D, Shim KN, Choe JW, Hong WS, Choi H. Effect of diet and Helicobacter pylori infection to the risk of early gastric cancer. J Epidemiol 2003;13:162-168. https://doi.org/10.2188/jea.13.162
  13. Shin A, Shin HR, Kang D, Park SK, Kim CS, Yoo KY. A nested case-control study of the association of Helicobacter pylori infection with gastric adenocarcinoma in Korea. Br J Cancer 2005;92:1273-1275. https://doi.org/10.1038/sj.bjc.6602467
  14. Gwack J, Shin A, Kim CS, Ko KP, Kim Y, Jun JK, et al. CagAproducing Helicobacter pylori and increased risk of gastric cancer: a nested case-control study in Korea. Br J Cancer 2006;95:639-641. https://doi.org/10.1038/sj.bjc.6603309
  15. Yim JY, Kim N, Choi SH, Kim YS, Cho KR, Kim SS, et al. Seroprevalence of Helicobacter pylori in South Korea. Helicobacter 2007;12:333-343. https://doi.org/10.1111/j.1523-5378.2007.00504.x
  16. Secretan B, Straif K, Baan R, Grosse Y, El Ghissassi F, Bouvard V, et al; WHO International Agency for Research on Cancer Monograph Working Group. A review of human carcinogens- -Part E: tobacco, areca nut, alcohol, coal smoke, and salted fish. Lancet Oncol 2009;10:1033-1034. https://doi.org/10.1016/S1470-2045(09)70326-2
  17. Kim Y, Shin A, Gwack J, Jun JK, Park SK, Kang D, et al. Cigarette smoking and gastric cancer risk in a community-based cohort study in Korea. J Prev Med Public Health 2007;40:467-474. https://doi.org/10.3961/jpmph.2007.40.6.467
  18. Yun YH, Jung KW, Bae JM, Lee JS, Shin SA, Park SM, et al. Cigarette smoking and cancer incidence risk in adult men: National Health Insurance Corporation Study. Cancer Detect Prev 2005;29:15-24. https://doi.org/10.1016/j.cdp.2004.08.006
  19. Jee SH, Samet JM, Ohrr H, Kim JH, Kim IS. Smoking and cancer risk in Korean men and women. Cancer Causes Control 2004;15:341-348.
  20. Parkin DM, Pisani P, Ferlay J. Estimates of the worldwide incidence of eighteen major cancers in 1985. Int J Cancer 1993;54:594-606. https://doi.org/10.1002/ijc.2910540413
  21. Shikata K, Doi Y, Yonemoto K, Arima H, Ninomiya T, Kubo M, et al. Population-based prospective study of the combined infl uence of cigarette smoking and Helicobacter pylori infection on gastric cancer incidence: the Hisayama Study. Am J Epidemiol 2008;168:1409-1415. https://doi.org/10.1093/aje/kwn276
  22. Lee H, Yoon SJ, Ahn HS. Measuring the burden of major cancers due to smoking in Korea. Cancer Sci 2006;97:530-534. https://doi.org/10.1111/j.1349-7006.2006.00205.x
  23. Report on National Health and Nutritional Examination, 1969- 2005. Ministry of Health and Welfare 2007.
  24. WHO/FAO Expert Consultation, ed. Diet, Nutrition and the Prevention of Chronic Diseases. 2003 WHO Technical Report Series No. 916. Geneva, Switzerland: World Health Organization, 2003.
  25. World Cancer Research Fund, American Institute for Cancer Research, eds. Food, Nutrition, Physical Activity, and the Prevention of Cancer: a Global Perspective. Washington DC: World Cancer Research Fund, 2007.
  26. Park B, Shin A, Park SK, Ko KP, Ma SH, Lee EH, et al. Ecological study for refrigerator use, salt, vegetable, and fruit intakes, and gastric cancer. Cancer Causes Control 2011 Jul 30. [Epub ahead of print].
  27. Kim J, Park S, Nam BH. Gastric cancer and salt preference: a population-based cohort study in Korea. Am J Clin Nutr 2010;91:1289-1293 https://doi.org/10.3945/ajcn.2009.28732
  28. Nan HM, Park JW, Song YJ, Yun HY, Park JS, Hyun T, et al. Kimchi and soybean pastes are risk factors of gastric cancer. World J Gastroenterol 2005;11:3175-3181. https://doi.org/10.3748/wjg.v11.i21.3175
  29. Lee S, Kang D, Hong WS, Shim KN, Choe JW, Choi H. Dietary habit and Helicobacter pylori infection in early gastric cancer patient. Cancer Res Treat 2002;34:104-110. https://doi.org/10.4143/crt.2002.34.2.104
  30. Kim HJ, Chang WK, Kim MK, Lee SS, Choi BY. Dietary factors and gastric cancer in Korea: a case-control study. Int J Cancer 2002;97:531-535. https://doi.org/10.1002/ijc.10111
  31. Lee JK, Park BJ, Yoo KY, Ahn YO. Dietary factors and stomach cancer: a case-control study in Korea. Int J Epidemiol 1995;24:33-41. https://doi.org/10.1093/ije/24.1.33
  32. Kono S, Hirohata T. Nutrition and stomach cancer. Cancer Causes Control 1996;7:41-55. https://doi.org/10.1007/BF00115637
  33. Kim HJ, Lim SY, Lee JS, Park S, Shin A, Choi BY, et al. Fresh and pickled vegetable consumption and gastric cancer in Japanese and Korean populations: a meta-analysis of observational studies. Cancer Sci 2010;101:508-516. https://doi.org/10.1111/j.1349-7006.2009.01374.x
  34. Messina MJ, Persky V, Setchell KD, Barnes S. Soy intake and cancer risk: a review of the in vitro and in vivo data. Nutr Cancer 1994;21:113-131. https://doi.org/10.1080/01635589409514310
  35. Kim J, Kang M, Lee JS, Inoue M, Sasazuki S, Tsugane S. Fermented and non-fermented soy food consumption and gastric cancer in Japanese and Korean populations: a meta-analysis of observational studies. Cancer Sci 2011;102:231-244. https://doi.org/10.1111/j.1349-7006.2010.01770.x
  36. Ko KP, Park SK, Park B, Yang JJ, Cho LY, Kang C, et al. Isofl avones from phytoestrogens and gastric cancer risk: a nested case-control study within the Korean Multicenter Cancer Cohort. Cancer Epidemiol Biomarkers Prev 2010;19:1292-1392. https://doi.org/10.1158/1055-9965.EPI-09-1004
  37. Goldman R, Shields PG. Food mutagens. J Nutr 2003;133(Suppl 3):965S-973S. https://doi.org/10.1093/jn/133.3.965S
  38. Sinha R, Rothman N. Exposure assessment of heterocyclic amines (HCAs) in epidemiologic studies. Mutat Res 1997;376:195-202. https://doi.org/10.1016/S0027-5107(97)00043-2
  39. Yoo KY. Cancer control activities in the Republic of Korea. Jpn J Clin Oncol 2008;38:327-333. https://doi.org/10.1093/jjco/hyn026
  40. Kim Y, Jun JK, Choi KS, Lee HY, Park EC. Overview of the National Cancer screening programme and the cancer screening status in Korea. Asian Pac J Cancer Prev 2011;12:725-730.
  41. Choi KS, Jun JK, Lee HY, Park S, Jung KW, Han MA, et al. Performance of gastric cancer screening by endoscopy testing through the National Cancer Screening Program of Korea. Cancer Sci 2011;102:1559-1564. https://doi.org/10.1111/j.1349-7006.2011.01982.x

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  86. Trends in Gastric Cancer Incidence According to the Clinicopathological Characteristics in Korea, 1999-2014 vol.50, pp.4, 2011, https://doi.org/10.4143/crt.2017.464
  87. Comparative Proteomic Profiling of Tumor-Associated Proteins in Human Gastric Cancer Cells Treated with Pectolinarigenin vol.10, pp.11, 2011, https://doi.org/10.3390/nu10111596
  88. Usefulness of OLGA and OLGIM system not only for intestinal type but also for diffuse type of gastric cancer, and no interaction among the gastric cancer risk factors vol.23, pp.6, 2018, https://doi.org/10.1111/hel.12542
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  90. Nature versus nurture: the impact of nativity and site of treatment on survival for gastric cancer vol.22, pp.3, 2011, https://doi.org/10.1007/s10120-018-0869-z
  91. Prognostic analysis and liver metastases relevant factors after gastric and hepatic surgical treatment in gastric cancer patients with metachronous liver metastases: a population-based study vol.188, pp.2, 2011, https://doi.org/10.1007/s11845-018-1864-4
  92. Dietary intake assessment of macro, trace, and toxic elements via consumption of kimchi in South Korea vol.99, pp.14, 2011, https://doi.org/10.1002/jsfa.9926
  93. Hepatic Arterial Infusion Oxaliplatin Plus Oral S-1 Chemotherapy in Gastric Cancer with Unresectable Liver Metastases: A Case Series and Literature Review vol.12, pp.None, 2011, https://doi.org/10.2147/cmar.s233123
  94. Clinical Practice Guidelines for Functional Dyspepsia in Korea vol.26, pp.1, 2011, https://doi.org/10.5056/jnm19209
  95. Subacute feeding toxicity of low‐sodium sausages manufactured with sodium substitutes and biopolymer‐encapsulated saltwort (Salicornia herbacea) in a mouse model vol.100, pp.2, 2011, https://doi.org/10.1002/jsfa.10087
  96. Sports, Instagram, and conflict talk in Englishes vol.39, pp.1, 2020, https://doi.org/10.1111/weng.12449
  97. The effectiveness of proton beam therapy for liver metastatic recurrence in gastric cancer patients vol.50, pp.8, 2020, https://doi.org/10.1093/jjco/hyaa052
  98. Comparative proteomic analysis uncovers potential biomarkers involved in the anticancer effect of Scutellarein in human gastric cancer cells vol.44, pp.3, 2011, https://doi.org/10.3892/or.2020.7677
  99. Increased Risk of Severe Gastric Symptoms by Virulence Factors vacAs1c, alpA, babA2, and hopZ in Helicobacter pylori Infection vol.31, pp.3, 2021, https://doi.org/10.4014/jmb.2101.01023
  100. Clinical Practice Guidelines for the Treatment of Functional Dyspepsia in Korea vol.96, pp.2, 2021, https://doi.org/10.3904/kjm.2021.96.2.116